Comprehensive review of 2-ethyl-1-hexanol as an indoor air pollutant Article Swipe
Takanari Wakayama
,
Yuki Ito
,
Kiyoshi Sakai
,
Mio Miyake
,
Eiji Shibata
,
Hiroyuki Ohno
,
Michihiro Kamijima
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1002/1348-9585.12017
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1002/1348-9585.12017
Objectives 2-Ethyl-1-hexanol (2EH), a fragrance ingredient and a raw material for the production of plasticizer di(2-ethylhexyl) phthalate, is responsible for sick building syndrome (SBS). This review aims to clarify the 2EH characteristics as an indoor air pollutant such as indoor air concentration, emission mechanism, toxicity, and clinical effects. Methods Scientific publications in English that has been made available on PubMed as of June 2018 and ad hoc publications in regional languages were reviewed. Results Inhalation exposure to 2EH caused mucous membrane irritation in the eyes, nose, and throat in experimental animals. Studies in human volunteers revealed an increase in olfactory irritation and eye discomfort. There has been increasing evidence of 2EH being present in indoor air in buildings. The primary sources of 2EH emissions are not building materials themselves, but instead the hydrolysis of plasticizers and flooring adhesives. In particular, compounds like di(2-ethylhexyl) phthalate present in polyvinyl chloride flooring materials are hydrolyzed upon contact with alkaline moisture-containing concrete floors. That being said, it may be observed that indoor concentrations of 2EH increased every year during summer. Conclusions Unlike other volatile organic compounds that cause SBS, 2EH can be retained in indoor air for long durations, increasing the likelihood of causing undesirable health effects in building occupants exposed to it. As a precautionary measure, it is important to use flooring materials that do not emit 2EH by hydrolysis, or to dry concrete before covering with flooring materials.
Related Topics
Concepts
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1002/1348-9585.12017
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1348-9585.12017
- OA Status
- gold
- Cited By
- 63
- References
- 161
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2912256801
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2912256801Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1002/1348-9585.12017Digital Object Identifier
- Title
-
Comprehensive review of 2-ethyl-1-hexanol as an indoor air pollutantWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2019Year of publication
- Publication date
-
2019-01-01Full publication date if available
- Authors
-
Takanari Wakayama, Yuki Ito, Kiyoshi Sakai, Mio Miyake, Eiji Shibata, Hiroyuki Ohno, Michihiro KamijimaList of authors in order
- Landing page
-
https://doi.org/10.1002/1348-9585.12017Publisher landing page
- PDF URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1348-9585.12017Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1348-9585.12017Direct OA link when available
- Concepts
-
Environmental science, Pollutant, Environmental chemistry, Air pollutants, Environmental health, Air pollution, Chemistry, Medicine, Organic chemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
63Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 11, 2024: 13, 2023: 17, 2022: 8, 2021: 7Per-year citation counts (last 5 years)
- References (count)
-
161Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W2912256801 |
|---|---|
| doi | https://doi.org/10.1002/1348-9585.12017 |
| ids.doi | https://doi.org/10.1002/1348-9585.12017 |
| ids.mag | 2912256801 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/30698348 |
| ids.openalex | https://openalex.org/W2912256801 |
| fwci | 2.72510165 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D000284 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Administration, Oral |
| mesh[1].qualifier_ui | Q000009 |
| mesh[1].descriptor_ui | D000393 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | adverse effects |
| mesh[1].descriptor_name | Air Pollutants |
| mesh[2].qualifier_ui | Q000009 |
| mesh[2].descriptor_ui | D016902 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | adverse effects |
| mesh[2].descriptor_name | Air Pollution, Indoor |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D000818 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Animals |
| mesh[4].qualifier_ui | Q000009 |
| mesh[4].descriptor_ui | D003252 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | adverse effects |
| mesh[4].descriptor_name | Construction Materials |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D004195 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Disease Models, Animal |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D005430 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Floors and Floorcoverings |
| mesh[7].qualifier_ui | Q000009 |
| mesh[7].descriptor_ui | D000441 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | adverse effects |
| mesh[7].descriptor_name | Hexanols |
| mesh[8].qualifier_ui | Q000493 |
| mesh[8].descriptor_ui | D000441 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | pharmacokinetics |
| mesh[8].descriptor_name | Hexanols |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D006801 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Humans |
| mesh[10].qualifier_ui | Q000009 |
| mesh[10].descriptor_ui | D019570 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | adverse effects |
| mesh[10].descriptor_name | Inhalation Exposure |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D051379 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Mice |
| mesh[12].qualifier_ui | Q000009 |
| mesh[12].descriptor_ui | D010968 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | adverse effects |
| mesh[12].descriptor_name | Plasticizers |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D051381 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Rats |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D000284 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Administration, Oral |
| mesh[15].qualifier_ui | Q000009 |
| mesh[15].descriptor_ui | D000393 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | adverse effects |
| mesh[15].descriptor_name | Air Pollutants |
| mesh[16].qualifier_ui | Q000009 |
| mesh[16].descriptor_ui | D016902 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | adverse effects |
| mesh[16].descriptor_name | Air Pollution, Indoor |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D000818 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Animals |
| mesh[18].qualifier_ui | Q000009 |
| mesh[18].descriptor_ui | D003252 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | adverse effects |
| mesh[18].descriptor_name | Construction Materials |
| mesh[19].qualifier_ui | |
| mesh[19].descriptor_ui | D004195 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | |
| mesh[19].descriptor_name | Disease Models, Animal |
| mesh[20].qualifier_ui | |
| mesh[20].descriptor_ui | D005430 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | |
| mesh[20].descriptor_name | Floors and Floorcoverings |
| mesh[21].qualifier_ui | Q000009 |
| mesh[21].descriptor_ui | D000441 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | adverse effects |
| mesh[21].descriptor_name | Hexanols |
| mesh[22].qualifier_ui | Q000493 |
| mesh[22].descriptor_ui | D000441 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | pharmacokinetics |
| mesh[22].descriptor_name | Hexanols |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D006801 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Humans |
| mesh[24].qualifier_ui | Q000009 |
| mesh[24].descriptor_ui | D019570 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | adverse effects |
| mesh[24].descriptor_name | Inhalation Exposure |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D051379 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Mice |
| mesh[26].qualifier_ui | Q000009 |
| mesh[26].descriptor_ui | D010968 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | adverse effects |
| mesh[26].descriptor_name | Plasticizers |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D051381 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Rats |
| type | review |
| title | Comprehensive review of 2-ethyl-1-hexanol as an indoor air pollutant |
| awards[0].id | https://openalex.org/G269131791 |
| awards[0].funder_id | https://openalex.org/F4320334764 |
| awards[0].funder_award_id | 16K15375 |
| awards[0].funder_display_name | Japan Society for the Promotion of Science |
| biblio.issue | 1 |
| biblio.volume | 61 |
| biblio.last_page | 35 |
| biblio.first_page | 19 |
| grants[0].funder | https://openalex.org/F4320334764 |
| grants[0].award_id | 16K15375 |
| grants[0].funder_display_name | Japan Society for the Promotion of Science |
| topics[0].id | https://openalex.org/T11002 |
| topics[0].field.id | https://openalex.org/fields/23 |
| topics[0].field.display_name | Environmental Science |
| topics[0].score | 0.9965999722480774 |
| topics[0].domain.id | https://openalex.org/domains/3 |
| topics[0].domain.display_name | Physical Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2307 |
| topics[0].subfield.display_name | Health, Toxicology and Mutagenesis |
| topics[0].display_name | Indoor Air Quality and Microbial Exposure |
| topics[1].id | https://openalex.org/T10190 |
| topics[1].field.id | https://openalex.org/fields/23 |
| topics[1].field.display_name | Environmental Science |
| topics[1].score | 0.9775000214576721 |
| topics[1].domain.id | https://openalex.org/domains/3 |
| topics[1].domain.display_name | Physical Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2307 |
| topics[1].subfield.display_name | Health, Toxicology and Mutagenesis |
| topics[1].display_name | Air Quality and Health Impacts |
| topics[2].id | https://openalex.org/T11821 |
| topics[2].field.id | https://openalex.org/fields/15 |
| topics[2].field.display_name | Chemical Engineering |
| topics[2].score | 0.9700000286102295 |
| topics[2].domain.id | https://openalex.org/domains/3 |
| topics[2].domain.display_name | Physical Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1508 |
| topics[2].subfield.display_name | Process Chemistry and Technology |
| topics[2].display_name | Odor and Emission Control Technologies |
| funders[0].id | https://openalex.org/F4320334764 |
| funders[0].ror | https://ror.org/00hhkn466 |
| funders[0].display_name | Japan Society for the Promotion of Science |
| is_xpac | False |
| apc_list.value | 1500 |
| apc_list.currency | USD |
| apc_list.value_usd | 1500 |
| apc_paid.value | 1500 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 1500 |
| concepts[0].id | https://openalex.org/C39432304 |
| concepts[0].level | 0 |
| concepts[0].score | 0.6477999687194824 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q188847 |
| concepts[0].display_name | Environmental science |
| concepts[1].id | https://openalex.org/C82685317 |
| concepts[1].level | 2 |
| concepts[1].score | 0.6353574395179749 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q19829510 |
| concepts[1].display_name | Pollutant |
| concepts[2].id | https://openalex.org/C107872376 |
| concepts[2].level | 1 |
| concepts[2].score | 0.4780329167842865 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q321355 |
| concepts[2].display_name | Environmental chemistry |
| concepts[3].id | https://openalex.org/C2987853052 |
| concepts[3].level | 3 |
| concepts[3].score | 0.47759199142456055 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q131123 |
| concepts[3].display_name | Air pollutants |
| concepts[4].id | https://openalex.org/C99454951 |
| concepts[4].level | 1 |
| concepts[4].score | 0.42364826798439026 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q932068 |
| concepts[4].display_name | Environmental health |
| concepts[5].id | https://openalex.org/C559116025 |
| concepts[5].level | 2 |
| concepts[5].score | 0.2730149030685425 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q131123 |
| concepts[5].display_name | Air pollution |
| concepts[6].id | https://openalex.org/C185592680 |
| concepts[6].level | 0 |
| concepts[6].score | 0.24563753604888916 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[6].display_name | Chemistry |
| concepts[7].id | https://openalex.org/C71924100 |
| concepts[7].level | 0 |
| concepts[7].score | 0.16986286640167236 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[7].display_name | Medicine |
| concepts[8].id | https://openalex.org/C178790620 |
| concepts[8].level | 1 |
| concepts[8].score | 0.05830904841423035 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q11351 |
| concepts[8].display_name | Organic chemistry |
| keywords[0].id | https://openalex.org/keywords/environmental-science |
| keywords[0].score | 0.6477999687194824 |
| keywords[0].display_name | Environmental science |
| keywords[1].id | https://openalex.org/keywords/pollutant |
| keywords[1].score | 0.6353574395179749 |
| keywords[1].display_name | Pollutant |
| keywords[2].id | https://openalex.org/keywords/environmental-chemistry |
| keywords[2].score | 0.4780329167842865 |
| keywords[2].display_name | Environmental chemistry |
| keywords[3].id | https://openalex.org/keywords/air-pollutants |
| keywords[3].score | 0.47759199142456055 |
| keywords[3].display_name | Air pollutants |
| keywords[4].id | https://openalex.org/keywords/environmental-health |
| keywords[4].score | 0.42364826798439026 |
| keywords[4].display_name | Environmental health |
| keywords[5].id | https://openalex.org/keywords/air-pollution |
| keywords[5].score | 0.2730149030685425 |
| keywords[5].display_name | Air pollution |
| keywords[6].id | https://openalex.org/keywords/chemistry |
| keywords[6].score | 0.24563753604888916 |
| keywords[6].display_name | Chemistry |
| keywords[7].id | https://openalex.org/keywords/medicine |
| keywords[7].score | 0.16986286640167236 |
| keywords[7].display_name | Medicine |
| keywords[8].id | https://openalex.org/keywords/organic-chemistry |
| keywords[8].score | 0.05830904841423035 |
| keywords[8].display_name | Organic chemistry |
| language | en |
| locations[0].id | doi:10.1002/1348-9585.12017 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S27728379 |
| locations[0].source.issn | 1341-9145, 1348-9585 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 1341-9145 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Journal of Occupational Health |
| locations[0].source.host_organization | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_name | Wiley |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320595 |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1348-9585.12017 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Journal of Occupational Health |
| locations[0].landing_page_url | https://doi.org/10.1002/1348-9585.12017 |
| locations[1].id | pmid:30698348 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Journal of occupational health |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/30698348 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:6499367 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | J Occup Health |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/6499367 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5010719545 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Takanari Wakayama |
| authorships[0].countries | JP |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Environmental Health, Nagoya City Public Health Research Institute , Nagoya, Japan |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I33858575 |
| authorships[0].affiliations[1].raw_affiliation_string | Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences , Nagoya, Japan |
| authorships[0].institutions[0].id | https://openalex.org/I33858575 |
| authorships[0].institutions[0].ror | https://ror.org/04wn7wc95 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I33858575 |
| authorships[0].institutions[0].country_code | JP |
| authorships[0].institutions[0].display_name | Nagoya City University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Takanari Wakayama |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Environmental Health, Nagoya City Public Health Research Institute , Nagoya, Japan, Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences , Nagoya, Japan |
| authorships[1].author.id | https://openalex.org/A5036439738 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-1617-1595 |
| authorships[1].author.display_name | Yuki Ito |
| authorships[1].countries | JP |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I33858575 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences , Nagoya, Japan |
| authorships[1].institutions[0].id | https://openalex.org/I33858575 |
| authorships[1].institutions[0].ror | https://ror.org/04wn7wc95 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I33858575 |
| authorships[1].institutions[0].country_code | JP |
| authorships[1].institutions[0].display_name | Nagoya City University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Yuki Ito |
| authorships[1].is_corresponding | True |
| authorships[1].raw_affiliation_strings | Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences , Nagoya, Japan |
| authorships[2].author.id | https://openalex.org/A5064024933 |
| authorships[2].author.orcid | https://orcid.org/0000-0001-7050-1191 |
| authorships[2].author.display_name | Kiyoshi Sakai |
| authorships[2].countries | JP |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I33858575 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences , Nagoya, Japan |
| authorships[2].affiliations[1].raw_affiliation_string | Department of Environmental Health, Nagoya City Public Health Research Institute , Nagoya, Japan |
| authorships[2].institutions[0].id | https://openalex.org/I33858575 |
| authorships[2].institutions[0].ror | https://ror.org/04wn7wc95 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I33858575 |
| authorships[2].institutions[0].country_code | JP |
| authorships[2].institutions[0].display_name | Nagoya City University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Kiyoshi Sakai |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Environmental Health, Nagoya City Public Health Research Institute , Nagoya, Japan, Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences , Nagoya, Japan |
| authorships[3].author.id | https://openalex.org/A5110766824 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Mio Miyake |
| authorships[3].countries | JP |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I33858575 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences , Nagoya, Japan |
| authorships[3].institutions[0].id | https://openalex.org/I33858575 |
| authorships[3].institutions[0].ror | https://ror.org/04wn7wc95 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I33858575 |
| authorships[3].institutions[0].country_code | JP |
| authorships[3].institutions[0].display_name | Nagoya City University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Mio Miyake |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences , Nagoya, Japan |
| authorships[4].author.id | https://openalex.org/A5112169169 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-7674-766X |
| authorships[4].author.display_name | Eiji Shibata |
| authorships[4].countries | JP |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I16528096 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Health and Psychosocial Medicine, Aichi Medical University School of Medicine , Nagakute, Japan |
| authorships[4].institutions[0].id | https://openalex.org/I16528096 |
| authorships[4].institutions[0].ror | https://ror.org/02h6cs343 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I16528096 |
| authorships[4].institutions[0].country_code | JP |
| authorships[4].institutions[0].display_name | Aichi Medical University |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Eiji Shibata |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Health and Psychosocial Medicine, Aichi Medical University School of Medicine , Nagakute, Japan |
| authorships[5].author.id | https://openalex.org/A5057087290 |
| authorships[5].author.orcid | https://orcid.org/0000-0001-9716-3495 |
| authorships[5].author.display_name | Hiroyuki Ohno |
| authorships[5].affiliations[0].raw_affiliation_string | Department of Environmental Health, Nagoya City Public Health Research Institute , Nagoya, Japan |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Hiroyuki Ohno |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Department of Environmental Health, Nagoya City Public Health Research Institute , Nagoya, Japan |
| authorships[6].author.id | https://openalex.org/A5076994948 |
| authorships[6].author.orcid | https://orcid.org/0000-0003-0670-8790 |
| authorships[6].author.display_name | Michihiro Kamijima |
| authorships[6].countries | JP |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I33858575 |
| authorships[6].affiliations[0].raw_affiliation_string | Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences , Nagoya, Japan |
| authorships[6].institutions[0].id | https://openalex.org/I33858575 |
| authorships[6].institutions[0].ror | https://ror.org/04wn7wc95 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I33858575 |
| authorships[6].institutions[0].country_code | JP |
| authorships[6].institutions[0].display_name | Nagoya City University |
| authorships[6].author_position | last |
| authorships[6].raw_author_name | Michihiro Kamijima |
| authorships[6].is_corresponding | True |
| authorships[6].raw_affiliation_strings | Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences , Nagoya, Japan |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1348-9585.12017 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Comprehensive review of 2-ethyl-1-hexanol as an indoor air pollutant |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T11002 |
| primary_topic.field.id | https://openalex.org/fields/23 |
| primary_topic.field.display_name | Environmental Science |
| primary_topic.score | 0.9965999722480774 |
| primary_topic.domain.id | https://openalex.org/domains/3 |
| primary_topic.domain.display_name | Physical Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2307 |
| primary_topic.subfield.display_name | Health, Toxicology and Mutagenesis |
| primary_topic.display_name | Indoor Air Quality and Microbial Exposure |
| related_works | https://openalex.org/W2392427421, https://openalex.org/W2717992184, https://openalex.org/W2141097079, https://openalex.org/W2944809113, https://openalex.org/W2391255140, https://openalex.org/W2156878610, https://openalex.org/W142713682, https://openalex.org/W4286275426, https://openalex.org/W2388169538, https://openalex.org/W2772399164 |
| cited_by_count | 63 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 11 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 13 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 17 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 8 |
| counts_by_year[4].year | 2021 |
| counts_by_year[4].cited_by_count | 7 |
| counts_by_year[5].year | 2020 |
| counts_by_year[5].cited_by_count | 5 |
| counts_by_year[6].year | 2019 |
| counts_by_year[6].cited_by_count | 2 |
| locations_count | 3 |
| best_oa_location.id | doi:10.1002/1348-9585.12017 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S27728379 |
| best_oa_location.source.issn | 1341-9145, 1348-9585 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 1341-9145 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Journal of Occupational Health |
| best_oa_location.source.host_organization | https://openalex.org/P4310320595 |
| best_oa_location.source.host_organization_name | Wiley |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1348-9585.12017 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Journal of Occupational Health |
| best_oa_location.landing_page_url | https://doi.org/10.1002/1348-9585.12017 |
| primary_location.id | doi:10.1002/1348-9585.12017 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S27728379 |
| primary_location.source.issn | 1341-9145, 1348-9585 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 1341-9145 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Journal of Occupational Health |
| primary_location.source.host_organization | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_name | Wiley |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1348-9585.12017 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Journal of Occupational Health |
| primary_location.landing_page_url | https://doi.org/10.1002/1348-9585.12017 |
| publication_date | 2019-01-01 |
| publication_year | 2019 |
| referenced_works | https://openalex.org/W2117924563, https://openalex.org/W2081938632, https://openalex.org/W2040315226, https://openalex.org/W2081256923, https://openalex.org/W2151524945, https://openalex.org/W1994821799, https://openalex.org/W2094136375, https://openalex.org/W2977088446, https://openalex.org/W2088510812, https://openalex.org/W2015505106, https://openalex.org/W2428390994, https://openalex.org/W1996546908, https://openalex.org/W2127433183, https://openalex.org/W2011702549, https://openalex.org/W2016168734, https://openalex.org/W1964003785, https://openalex.org/W1970738003, https://openalex.org/W2323203643, https://openalex.org/W2026512463, https://openalex.org/W88303699, https://openalex.org/W2259640863, https://openalex.org/W2002611417, https://openalex.org/W2070646012, https://openalex.org/W2089855787, https://openalex.org/W2112794291, https://openalex.org/W2019666600, https://openalex.org/W2333282863, https://openalex.org/W2079499441, https://openalex.org/W2091883807, https://openalex.org/W2118185379, https://openalex.org/W2102262668, https://openalex.org/W2050478983, https://openalex.org/W2140690631, https://openalex.org/W2079164098, https://openalex.org/W2016052041, https://openalex.org/W2026183909, https://openalex.org/W1986088623, https://openalex.org/W2049171029, https://openalex.org/W39864448, https://openalex.org/W2168612746, https://openalex.org/W2171790558, https://openalex.org/W2079748528, https://openalex.org/W1996696356, https://openalex.org/W2065205444, https://openalex.org/W2029965093, https://openalex.org/W2089512417, https://openalex.org/W1981568524, https://openalex.org/W2106029018, https://openalex.org/W609137217, https://openalex.org/W2038490743, https://openalex.org/W2329809074, https://openalex.org/W1908410836, https://openalex.org/W2017316927, https://openalex.org/W1970425815, https://openalex.org/W2079029416, https://openalex.org/W2088379727, https://openalex.org/W187582229, https://openalex.org/W2086324355, https://openalex.org/W4302474755, https://openalex.org/W2040056057, https://openalex.org/W2142816253, https://openalex.org/W2399630583, https://openalex.org/W2047935610, https://openalex.org/W2078425581, https://openalex.org/W1971315969, https://openalex.org/W2012437256, https://openalex.org/W2103439647, https://openalex.org/W2006977029, https://openalex.org/W6725262841, https://openalex.org/W831464196, https://openalex.org/W2308510141, https://openalex.org/W2553404014, https://openalex.org/W1966153792, https://openalex.org/W1976366300, https://openalex.org/W2319540622, https://openalex.org/W2093617348, https://openalex.org/W1976515655, https://openalex.org/W2409633628, https://openalex.org/W6675374907, https://openalex.org/W2315362414, https://openalex.org/W2109314045, https://openalex.org/W1993622376, https://openalex.org/W1983934624, https://openalex.org/W1968115285, https://openalex.org/W4210966962, https://openalex.org/W2067282768, https://openalex.org/W2326598092, https://openalex.org/W1990514914, https://openalex.org/W6697431070, https://openalex.org/W1501688361, https://openalex.org/W1969480297, https://openalex.org/W2020398916, https://openalex.org/W2079301969, https://openalex.org/W2004763230, https://openalex.org/W2325229829, https://openalex.org/W6679671841, https://openalex.org/W1983531798, https://openalex.org/W2005807397, https://openalex.org/W1973568948, https://openalex.org/W2129977702, https://openalex.org/W1536729517, https://openalex.org/W2103883464, https://openalex.org/W2038137840, https://openalex.org/W1979069528, https://openalex.org/W2078169722, https://openalex.org/W2082981840, https://openalex.org/W2091670093, https://openalex.org/W1971994915, https://openalex.org/W2167864792, https://openalex.org/W2041191405, https://openalex.org/W1990073317, https://openalex.org/W2059459821, https://openalex.org/W2145704885, https://openalex.org/W2064851649, https://openalex.org/W2083352982, https://openalex.org/W2061335656, https://openalex.org/W2034199374, https://openalex.org/W2032090234, https://openalex.org/W2037060949, https://openalex.org/W2077727773, https://openalex.org/W6699235108, https://openalex.org/W2006680692, https://openalex.org/W2034270582, https://openalex.org/W2053282821, https://openalex.org/W2092122739, https://openalex.org/W6673111023, https://openalex.org/W1597711166, https://openalex.org/W1991045271, https://openalex.org/W2006950493, https://openalex.org/W1996520281, https://openalex.org/W2092116576, https://openalex.org/W2050813884, https://openalex.org/W2067355567, https://openalex.org/W2041609494, https://openalex.org/W2060640048, https://openalex.org/W1996890971, https://openalex.org/W2027906995, https://openalex.org/W2518178147, https://openalex.org/W2329899832, https://openalex.org/W1965373870, https://openalex.org/W6691987503, https://openalex.org/W2046791941, https://openalex.org/W2079207671, https://openalex.org/W2045175945, https://openalex.org/W2097049516, https://openalex.org/W2086932758, https://openalex.org/W3120655587, https://openalex.org/W2090270189, https://openalex.org/W1599518542, https://openalex.org/W2301102222, https://openalex.org/W2315419119, https://openalex.org/W2135526016, https://openalex.org/W4241256488, https://openalex.org/W4230262688, https://openalex.org/W2884338870, https://openalex.org/W2581192620, https://openalex.org/W2005567947, https://openalex.org/W2560065326, https://openalex.org/W2092315515, https://openalex.org/W2508322642, https://openalex.org/W2255073962 |
| referenced_works_count | 161 |
| abstract_inverted_index.a | 4, 8, 211 |
| abstract_inverted_index.As | 210 |
| abstract_inverted_index.In | 139 |
| abstract_inverted_index.ad | 66 |
| abstract_inverted_index.an | 34, 97 |
| abstract_inverted_index.as | 33, 39, 61 |
| abstract_inverted_index.be | 165, 188 |
| abstract_inverted_index.by | 226 |
| abstract_inverted_index.do | 222 |
| abstract_inverted_index.in | 52, 69, 83, 89, 93, 99, 114, 117, 146, 190, 204 |
| abstract_inverted_index.is | 18, 215 |
| abstract_inverted_index.it | 163, 214 |
| abstract_inverted_index.of | 14, 62, 110, 122, 134, 170, 199 |
| abstract_inverted_index.on | 59 |
| abstract_inverted_index.or | 228 |
| abstract_inverted_index.to | 28, 77, 208, 217, 229 |
| abstract_inverted_index.2EH | 31, 78, 111, 123, 171, 186, 225 |
| abstract_inverted_index.The | 119 |
| abstract_inverted_index.air | 36, 41, 116, 192 |
| abstract_inverted_index.and | 7, 46, 65, 87, 102, 136 |
| abstract_inverted_index.are | 125, 151 |
| abstract_inverted_index.but | 130 |
| abstract_inverted_index.can | 187 |
| abstract_inverted_index.dry | 230 |
| abstract_inverted_index.eye | 103 |
| abstract_inverted_index.for | 11, 20, 193 |
| abstract_inverted_index.has | 55, 106 |
| abstract_inverted_index.hoc | 67 |
| abstract_inverted_index.it. | 209 |
| abstract_inverted_index.may | 164 |
| abstract_inverted_index.not | 126, 223 |
| abstract_inverted_index.raw | 9 |
| abstract_inverted_index.the | 12, 30, 84, 132, 197 |
| abstract_inverted_index.use | 218 |
| abstract_inverted_index.2018 | 64 |
| abstract_inverted_index.June | 63 |
| abstract_inverted_index.SBS, | 185 |
| abstract_inverted_index.That | 160 |
| abstract_inverted_index.This | 25 |
| abstract_inverted_index.aims | 27 |
| abstract_inverted_index.been | 56, 107 |
| abstract_inverted_index.emit | 224 |
| abstract_inverted_index.like | 142 |
| abstract_inverted_index.long | 194 |
| abstract_inverted_index.made | 57 |
| abstract_inverted_index.sick | 21 |
| abstract_inverted_index.such | 38 |
| abstract_inverted_index.that | 54, 167, 183, 221 |
| abstract_inverted_index.upon | 153 |
| abstract_inverted_index.were | 72 |
| abstract_inverted_index.with | 155, 234 |
| abstract_inverted_index.year | 174 |
| abstract_inverted_index.There | 105 |
| abstract_inverted_index.being | 112, 161 |
| abstract_inverted_index.cause | 184 |
| abstract_inverted_index.every | 173 |
| abstract_inverted_index.eyes, | 85 |
| abstract_inverted_index.human | 94 |
| abstract_inverted_index.nose, | 86 |
| abstract_inverted_index.other | 179 |
| abstract_inverted_index.said, | 162 |
| abstract_inverted_index.(2EH), | 3 |
| abstract_inverted_index.(SBS). | 24 |
| abstract_inverted_index.PubMed | 60 |
| abstract_inverted_index.Unlike | 178 |
| abstract_inverted_index.before | 232 |
| abstract_inverted_index.caused | 79 |
| abstract_inverted_index.during | 175 |
| abstract_inverted_index.health | 202 |
| abstract_inverted_index.indoor | 35, 40, 115, 168, 191 |
| abstract_inverted_index.mucous | 80 |
| abstract_inverted_index.review | 26 |
| abstract_inverted_index.throat | 88 |
| abstract_inverted_index.English | 53 |
| abstract_inverted_index.Methods | 49 |
| abstract_inverted_index.Results | 74 |
| abstract_inverted_index.Studies | 92 |
| abstract_inverted_index.causing | 200 |
| abstract_inverted_index.clarify | 29 |
| abstract_inverted_index.contact | 154 |
| abstract_inverted_index.effects | 203 |
| abstract_inverted_index.exposed | 207 |
| abstract_inverted_index.floors. | 159 |
| abstract_inverted_index.instead | 131 |
| abstract_inverted_index.organic | 181 |
| abstract_inverted_index.present | 113, 145 |
| abstract_inverted_index.primary | 120 |
| abstract_inverted_index.sources | 121 |
| abstract_inverted_index.summer. | 176 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.alkaline | 156 |
| abstract_inverted_index.animals. | 91 |
| abstract_inverted_index.building | 22, 127, 205 |
| abstract_inverted_index.chloride | 148 |
| abstract_inverted_index.clinical | 47 |
| abstract_inverted_index.concrete | 158, 231 |
| abstract_inverted_index.covering | 233 |
| abstract_inverted_index.effects. | 48 |
| abstract_inverted_index.emission | 43 |
| abstract_inverted_index.evidence | 109 |
| abstract_inverted_index.exposure | 76 |
| abstract_inverted_index.flooring | 137, 149, 219, 235 |
| abstract_inverted_index.increase | 98 |
| abstract_inverted_index.material | 10 |
| abstract_inverted_index.measure, | 213 |
| abstract_inverted_index.membrane | 81 |
| abstract_inverted_index.observed | 166 |
| abstract_inverted_index.regional | 70 |
| abstract_inverted_index.retained | 189 |
| abstract_inverted_index.revealed | 96 |
| abstract_inverted_index.syndrome | 23 |
| abstract_inverted_index.volatile | 180 |
| abstract_inverted_index.available | 58 |
| abstract_inverted_index.compounds | 141, 182 |
| abstract_inverted_index.emissions | 124 |
| abstract_inverted_index.fragrance | 5 |
| abstract_inverted_index.important | 216 |
| abstract_inverted_index.increased | 172 |
| abstract_inverted_index.languages | 71 |
| abstract_inverted_index.materials | 128, 150, 220 |
| abstract_inverted_index.occupants | 206 |
| abstract_inverted_index.olfactory | 100 |
| abstract_inverted_index.phthalate | 144 |
| abstract_inverted_index.pollutant | 37 |
| abstract_inverted_index.polyvinyl | 147 |
| abstract_inverted_index.reviewed. | 73 |
| abstract_inverted_index.toxicity, | 45 |
| abstract_inverted_index.Inhalation | 75 |
| abstract_inverted_index.Objectives | 1 |
| abstract_inverted_index.Scientific | 50 |
| abstract_inverted_index.adhesives. | 138 |
| abstract_inverted_index.buildings. | 118 |
| abstract_inverted_index.durations, | 195 |
| abstract_inverted_index.hydrolysis | 133 |
| abstract_inverted_index.hydrolyzed | 152 |
| abstract_inverted_index.increasing | 108, 196 |
| abstract_inverted_index.ingredient | 6 |
| abstract_inverted_index.irritation | 82, 101 |
| abstract_inverted_index.likelihood | 198 |
| abstract_inverted_index.materials. | 236 |
| abstract_inverted_index.mechanism, | 44 |
| abstract_inverted_index.phthalate, | 17 |
| abstract_inverted_index.production | 13 |
| abstract_inverted_index.volunteers | 95 |
| abstract_inverted_index.Conclusions | 177 |
| abstract_inverted_index.discomfort. | 104 |
| abstract_inverted_index.hydrolysis, | 227 |
| abstract_inverted_index.particular, | 140 |
| abstract_inverted_index.plasticizer | 15 |
| abstract_inverted_index.responsible | 19 |
| abstract_inverted_index.themselves, | 129 |
| abstract_inverted_index.undesirable | 201 |
| abstract_inverted_index.experimental | 90 |
| abstract_inverted_index.plasticizers | 135 |
| abstract_inverted_index.publications | 51, 68 |
| abstract_inverted_index.precautionary | 212 |
| abstract_inverted_index.concentration, | 42 |
| abstract_inverted_index.concentrations | 169 |
| abstract_inverted_index.characteristics | 32 |
| abstract_inverted_index.di(2-ethylhexyl) | 16, 143 |
| abstract_inverted_index.2-Ethyl-1-hexanol | 2 |
| abstract_inverted_index.moisture-containing | 157 |
| cited_by_percentile_year.max | 100 |
| cited_by_percentile_year.min | 94 |
| corresponding_author_ids | https://openalex.org/A5036439738, https://openalex.org/A5076994948 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 7 |
| corresponding_institution_ids | https://openalex.org/I33858575 |
| citation_normalized_percentile.value | 0.86943357 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |