bioRxiv (Cold Spring Harbor Laboratory)
Computation-through-Dynamics Benchmark: Simulated datasets and quality metrics for dynamical models of neural activity
February 2025 • Christopher Versteeg, Jonathan McCart, Mitchell Ostrow, David M. Zoltowski, Clayton Washington, Laura Driscoll, Olivier Codol, Jonathan A. Michaels, …
Abstract A primary goal of systems neuroscience is to discover how ensembles of neurons transform inputs into goal-directed behavior, a process known as neural computation. A powerful framework for understanding neural computation uses neural dynamics – the rules that describe the temporal evolution of neural activity – to explain how goal-directed input-output transformations occur. As dynamical rules are not directly observable, we need computational models that can infer neural dynamics from recorded neural act…