Computational fluid dynamics evaluation of flow reversal treatment of giant basilar tip aneurysm Article Swipe
Martin Sandve Alnæs
,
Kent–André Mardal
,
S. J. Bakke
,
Angelika Sorteberg
·
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.1177/1591019915597415
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.1177/1591019915597415
Therapeutic parent artery flow reversal is a treatment option for giant, partially thrombosed basilar tip aneurysms. The effectiveness of this treatment has been variable and not yet studied by applying computational fluid dynamics. Computed tomography images and blood flow velocities acquired with transcranial Doppler ultrasonography were obtained prior to and after bilateral endovascular vertebral artery occlusion for a giant basilar tip aneurysm. Patient-specific geometries and velocity waveforms were used in computational fluid dynamics simulations in order to determine the velocity and wall shear stress changes induced by treatment. Therapeutic parent artery flow reversal lead to a dramatic increase in aneurysm inflow and wall shear stress (30 to 170 Pa) resulting in an increase in intra-aneurysmal circulation. The enlargement of the circulated area within the aneurysm led to a re-normalization of the wall shear stress and the aneurysm remained stable for more than 8 years thereafter. Therapeutic parent artery flow reversal can lead to unintended, potentially harmful changes in aneurysm inflow which can be quantified and possibly predicted by applying computational fluid dynamics.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1177/1591019915597415
- OA Status
- green
- Cited By
- 3
- References
- 16
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2340165936
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2340165936Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1177/1591019915597415Digital Object Identifier
- Title
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Computational fluid dynamics evaluation of flow reversal treatment of giant basilar tip aneurysmWork title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2015Year of publication
- Publication date
-
2015-08-07Full publication date if available
- Authors
-
Martin Sandve Alnæs, Kent–André Mardal, S. J. Bakke, Angelika SortebergList of authors in order
- Landing page
-
https://doi.org/10.1177/1591019915597415Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://www.ncbi.nlm.nih.gov/pmc/articles/4757336Direct OA link when available
- Concepts
-
Aneurysm, Medicine, Inflow, Blood flow, Basilar artery, Shear stress, Transcranial Doppler, Vertebral artery, Occlusion, Radiology, Surgery, Mechanics, PhysicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
3Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1, 2024: 1, 2018: 1Per-year citation counts (last 5 years)
- References (count)
-
16Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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