Connecting research and community: a methodological framework for investigating CMV transmission in childcare settings Article Swipe
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· 2025
· Open Access
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· DOI: https://doi.org/10.3389/fped.2025.1657706
The CMV Transmission and Immune Tracking (TransmIT) Study was developed to address critical gaps in understanding of cytomegalovirus (CMV) transmission dynamics in early education and care (EEC) settings. This two-stage, community-engaged study design integrates EEC center partnerships, digital study platforms, and data pipeline infrastructures to enable longitudinal virologic and immunologic surveillance in this high-exposure environment. Stage I focused on establishing foundational components of the study, including a geographically diverse EEC center network, culturally tailored recruitment strategies, a community advisory board, protocols for participant enrollment and saliva sample collection, and optimized laboratory assays to measure viral shedding in saliva. The study approach honed during Stage I is intended to support future longitudinal investigations into viral shedding patterns, immune responses, and co-infections among children and staff in EEC centers. This manuscript presents a methodological framework for conducting community-centered scalable research in early childhood settings with relevance for CMV and other infectious diseases of public health importance.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3389/fped.2025.1657706
- https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2025.1657706/pdf
- OA Status
- gold
- References
- 51
- OpenAlex ID
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Raw OpenAlex JSON
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https://openalex.org/W4415457726Canonical identifier for this work in OpenAlex
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- Title
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Connecting research and community: a methodological framework for investigating CMV transmission in childcare settingsWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-10-23Full publication date if available
- Authors
-
Karen Del’Olio, Anne Geiger, Jonathan G. Terry, C. O. Callaghan, Lauren Howe, Candyce Hamel, Delaney Platia, Alexandre Blake, Lisa Tran, Anne Davenport, Elizabeth Orvek, Stephen Lammi, Bruce Barton, Timothy F. Kowalik, John Holik, Anne M. Mirza, Olesea Cojohari, Kelsey Woods, Susan Druker, Syed Naeem, John Diaz‐Decaro, Madeleine Hayden, Iliana Leony Lasso, Juli Gulpinar, Sandeep Basnet, Lori Panther, Andrew Natenshon, Thejas Suvarna, Emma Harman, Kelley Bridges, Summer Schrader, Laura GibsonList of authors in order
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https://doi.org/10.3389/fped.2025.1657706Publisher landing page
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https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2025.1657706/pdfDirect link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2025.1657706/pdfDirect OA link when available
- Cited by
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0Total citation count in OpenAlex
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51Number of works referenced by this work
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