Considering the Influence of Coronary Motion on Artery-Specific Biomechanics Using Fluid–Structure Interaction Simulation Article Swipe
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· 2023
· Open Access
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· DOI: https://doi.org/10.1007/s10439-023-03214-0
The endothelium in the coronary arteries is subject to wall shear stress and vessel wall strain, which influences the biology of the arterial wall. This study presents vessel-specific fluid–structure interaction (FSI) models of three coronary arteries, using directly measured experimental geometries and boundary conditions. FSI models are used to provide a more physiologically complete representation of vessel biomechanics, and have been extended to include coronary bending to investigate its effect on shear and strain. FSI both without- and with-bending resulted in significant changes in all computed shear stress metrics compared to CFD ( p = 0.0001). Inclusion of bending within the FSI model produced highly significant changes in Time Averaged Wall Shear Stress (TAWSS) + 9.8% LAD, + 8.8% LCx, − 2.0% RCA; Oscillatory Shear Index (OSI) + 208% LAD, 0% LCx, + 2600% RCA; and transverse wall Shear Stress (tSS) + 180% LAD, + 150% LCx and + 200% RCA (all p < 0.0001). Vessel wall strain was homogenous in all directions without-bending but became highly anisotropic under bending. Changes in median cyclic strain magnitude were seen for all three vessels in every direction. Changes shown in the magnitude and distribution of shear stress and wall strain suggest that bending should be considered on a vessel-specific basis in analyses of coronary artery biomechanics.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1007/s10439-023-03214-0
- https://link.springer.com/content/pdf/10.1007/s10439-023-03214-0.pdf
- OA Status
- hybrid
- Cited By
- 12
- References
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- Related Works
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- OpenAlex ID
- https://openalex.org/W4383998987
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4383998987Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1007/s10439-023-03214-0Digital Object Identifier
- Title
-
Considering the Influence of Coronary Motion on Artery-Specific Biomechanics Using Fluid–Structure Interaction SimulationWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-07-12Full publication date if available
- Authors
-
Nicholas A. Fogell, M. Patel, Pan Yang, Roosje M. Ruis, David B. Garcia, Jarka Naser, Fotios Savvopoulos, Clint Davies Taylor, Anouk L. Post, Ryan M. Pedrigi, Ranil de Silva, Rob KramsList of authors in order
- Landing page
-
https://doi.org/10.1007/s10439-023-03214-0Publisher landing page
- PDF URL
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https://link.springer.com/content/pdf/10.1007/s10439-023-03214-0.pdfDirect link to full text PDF
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
- OA URL
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https://link.springer.com/content/pdf/10.1007/s10439-023-03214-0.pdfDirect OA link when available
- Concepts
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Shear stress, Biomechanics, Bending, Materials science, Shear (geology), Coronary arteries, Structural engineering, Artery, Biomedical engineering, Anatomy, Composite material, Cardiology, Medicine, EngineeringTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
12Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 7, 2024: 3, 2023: 2Per-year citation counts (last 5 years)
- References (count)
-
52Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.should | 202 |
| abstract_inverted_index.strain | 158, 175, 198 |
| abstract_inverted_index.stress | 12, 88, 195 |
| abstract_inverted_index.vessel | 14, 57 |
| abstract_inverted_index.within | 100 |
| abstract_inverted_index.(TAWSS) | 114 |
| abstract_inverted_index.Changes | 171, 186 |
| abstract_inverted_index.bending | 66, 99, 201 |
| abstract_inverted_index.biology | 20 |
| abstract_inverted_index.changes | 83, 107 |
| abstract_inverted_index.include | 64 |
| abstract_inverted_index.metrics | 89 |
| abstract_inverted_index.provide | 50 |
| abstract_inverted_index.strain, | 16 |
| abstract_inverted_index.strain. | 74 |
| abstract_inverted_index.subject | 8 |
| abstract_inverted_index.suggest | 199 |
| abstract_inverted_index.vessels | 182 |
| abstract_inverted_index.0.0001). | 96, 155 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Averaged | 110 |
| abstract_inverted_index.analyses | 210 |
| abstract_inverted_index.arterial | 23 |
| abstract_inverted_index.arteries | 6 |
| abstract_inverted_index.bending. | 170 |
| abstract_inverted_index.boundary | 43 |
| abstract_inverted_index.compared | 90 |
| abstract_inverted_index.complete | 54 |
| abstract_inverted_index.computed | 86 |
| abstract_inverted_index.coronary | 5, 35, 65, 212 |
| abstract_inverted_index.directly | 38 |
| abstract_inverted_index.extended | 62 |
| abstract_inverted_index.measured | 39 |
| abstract_inverted_index.presents | 27 |
| abstract_inverted_index.produced | 104 |
| abstract_inverted_index.resulted | 80 |
| abstract_inverted_index.without- | 77 |
| abstract_inverted_index.Inclusion | 97 |
| abstract_inverted_index.arteries, | 36 |
| abstract_inverted_index.magnitude | 176, 190 |
| abstract_inverted_index.considered | 204 |
| abstract_inverted_index.direction. | 185 |
| abstract_inverted_index.directions | 163 |
| abstract_inverted_index.geometries | 41 |
| abstract_inverted_index.homogenous | 160 |
| abstract_inverted_index.influences | 18 |
| abstract_inverted_index.transverse | 137 |
| abstract_inverted_index.Oscillatory | 124 |
| abstract_inverted_index.anisotropic | 168 |
| abstract_inverted_index.conditions. | 44 |
| abstract_inverted_index.endothelium | 2 |
| abstract_inverted_index.interaction | 30 |
| abstract_inverted_index.investigate | 68 |
| abstract_inverted_index.significant | 82, 106 |
| abstract_inverted_index.distribution | 192 |
| abstract_inverted_index.experimental | 40 |
| abstract_inverted_index.with-bending | 79 |
| abstract_inverted_index.biomechanics, | 58 |
| abstract_inverted_index.biomechanics. | 214 |
| abstract_inverted_index.representation | 55 |
| abstract_inverted_index.physiologically | 53 |
| abstract_inverted_index.vessel-specific | 28, 207 |
| abstract_inverted_index.without-bending | 164 |
| abstract_inverted_index.fluid–structure | 29 |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 94 |
| corresponding_author_ids | https://openalex.org/A5003248425 |
| countries_distinct_count | 3 |
| institutions_distinct_count | 12 |
| corresponding_institution_ids | https://openalex.org/I47508984 |
| citation_normalized_percentile.value | 0.94879742 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |