Construct Validation of the Dietary Inflammatory Index (DII) among Young College-Aged Women Article Swipe
YOU?
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· 2023
· Open Access
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· DOI: https://doi.org/10.3390/nu15214553
The Dietary Inflammatory Index (DII) is designed to assess the inflammatory potential of the diet. While previous research has utilized DII among college-aged women, no study to date has validated it in this population. We conducted a construct validation of DII among 393 healthy women aged 18–31 years against a robust panel of 14 inflammatory biomarkers, including CRP, IL-1β, IL-4, IL-6, IL-10, and TNF-α, which were used in the development of DII. Three linear regression models were constructed: (1) an age-adjusted model, (2) the most parsimonious model based on likelihood ratio tests, and (3) a fully adjusted model for age, race, body mass index, waist circumference, physical activity, smoking status, and nonsteroidal anti-inflammatory drug use. DII was derived from the Harvard food frequency questionnaire and categorized into quartiles. Consistent with our hypothesis, DII was negatively and significantly associated with back-transformed IL-10 levels, confirming that a more pro-inflammatory diet was associated with lower levels of an anti-inflammatory cytokine (Model 3: Q4 vs. Q1 β = 0.62; 95% CI: 0.42, 0.93; p-trend = 0.04). While validated in other populations, DII may not be a suitable tool for assessing the inflammatory potential of the diet among college-aged women.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/nu15214553
- https://www.mdpi.com/2072-6643/15/21/4553/pdf?version=1698389954
- OA Status
- gold
- Cited By
- 6
- References
- 57
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4387971629
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4387971629Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/nu15214553Digital Object Identifier
- Title
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Construct Validation of the Dietary Inflammatory Index (DII) among Young College-Aged WomenWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-10-27Full publication date if available
- Authors
-
Deniz Azarmanesh, Jessica Pearlman, Elena T. Carbone, Janie DiNatale, Elizabeth R. Bertone‐JohnsonList of authors in order
- Landing page
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https://doi.org/10.3390/nu15214553Publisher landing page
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https://www.mdpi.com/2072-6643/15/21/4553/pdf?version=1698389954Direct link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://www.mdpi.com/2072-6643/15/21/4553/pdf?version=1698389954Direct OA link when available
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Construct (python library), Index (typography), Gerontology, Construct validity, Medicine, Internal medicine, Clinical psychology, Psychometrics, Computer science, World Wide Web, Programming languageTop concepts (fields/topics) attached by OpenAlex
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6Total citation count in OpenAlex
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2025: 5, 2024: 1Per-year citation counts (last 5 years)
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57Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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