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Clinical Epidemiology • Vol Volume 15
Controlling for Differential Regression-To-The-Mean via Propensity Scores: A Simulation Study
June 2023 • Chase D. Latour, Leah J. McGrath, Mary C. Clouser, Carrie M. Nielson, Ying Yu, Akhila Balasubramanian, Alexander Breskin, M. Alan Brookhart
These results suggest that differential RTM could be reasonably addressed by propensity score models with summaries of historical laboratory values. This approach can be easily applied to any comparative effectiveness or safety study, though investigators should carefully consider the best summary metric for their data.
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