Copper mediated one-pot synthesis of quinazolinones and exploration of piperazine linked quinazoline derivatives as anti-mycobacterial agents Article Swipe

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Satyaveni Malasala , Jitendra Gour , Mohammad Naiyaz Ahmad , Srikanth Gatadi , Manjulika Shukla , Grace Kaul , Amitava Dasgupta , Y.V. Madhavi , Sidharth Chopra , Srinivas Nanduri ·

YOU? · · 2020 · Open Access · · DOI: https://doi.org/10.1039/d0ra08644d

A facile method was developed for the synthesis of quinazolinone derivatives in a one-pot condensation reaction via in situ amine generation using ammonia as the amine source and with the formation of four new C–N bonds in good to excellent yields.

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Piperazine Chemistry Combinatorial chemistry Quinazoline Copper Organic chemistry

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Type: article
Language: en
Landing Page: https://doi.org/10.1039/d0ra08644d
PDF: https://pubs.rsc.org/en/content/articlepdf/2020/ra/d0ra08644d
OA Status: gold
Cited By: 14
References: 37
Related Works: 10
OpenAlex ID: https://openalex.org/W3112939036

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DOI: https://doi.org/10.1039/d0ra08644d

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Title: Copper mediated one-pot synthesis of quinazolinones and exploration of piperazine linked quinazoline derivatives as anti-mycobacterial agents

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Type: article

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Language: en

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Publication year: 2020

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Publication date: 2020-01-01

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Authors: Satyaveni Malasala, Jitendra Gour, Mohammad Naiyaz Ahmad, Srikanth Gatadi, Manjulika Shukla, Grace Kaul, Amitava Dasgupta, Y.V. Madhavi, Sidharth Chopra, Srinivas Nanduri

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Landing page: https://doi.org/10.1039/d0ra08644d

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PDF URL: https://pubs.rsc.org/en/content/articlepdf/2020/ra/d0ra08644d

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OA URL: https://pubs.rsc.org/en/content/articlepdf/2020/ra/d0ra08644d

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Concepts: Piperazine, Chemistry, Combinatorial chemistry, Quinazoline, Copper, Organic chemistry

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Cited by: 14

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Citations by year (recent): 2025: 5, 2024: 3, 2023: 2, 2022: 2, 2021: 2

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