Cost-effectiveness of repeat delayed imaging for spontaneous subarachnoid hemorrhage Article Swipe
Wenru Shang
,
Huajie Jin
,
Amisha Vastani
,
Asfand Baig Mirza
,
Benjamin Franklin Fisher
,
Neeraj Kalra
,
Ian Anderson
,
Ahilan Kailaya-Vasan
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1371/journal.pone.0289144
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1371/journal.pone.0289144
Background In patients with intracranial aneurysm presenting with spontaneous subarachnoid hemorrhage (SAH), 15% of them could be missed by the initial diagnostic imaging. Repeat delayed imaging can help to identify previously undetected aneurysms, however, the cost-effectiveness of this strategy remains uncertain. Objective The aim of this study is to assess the cost-effectiveness of repeat delayed imaging in patients with SAH who had a negative result during their initial imaging. Methods A Markov model was developed to estimate the lifetime costs and quality-adjusted life-year (QALY) for patients who received or not received repeat delayed imaging. The analyses were conducted from a healthcare perspective, with costs reported in UK pounds and expressed in 2020 values. Extensive sensitivity analyses were performed to assess the robustness of the results. Results The base case incremental cost-effectiveness ratio (ICER) of repeat delayed imaging is £9,314 per QALY compared to no-repeat delayed imaging. This ICER is below the National Institute for Health and Care Excellence (NICE) £20,000 per QALY willingness-to-pay threshold. At the NICE willingness-to-pay threshold of £20,000 per QALY, the probability that repeat delayed imaging is most cost-effective is 0.81. The results are sensitive to age, the utility of survived patients with a favorable outcome, the sensitivity of repeat delayed imaging, and the prevalence of aneurysm. Conclusions This study showed that, in the UK, it is cost-effective to provide repeat delayed imaging using computed tomographic angiography (CTA) for patients with SAH who had a negative result in their initial imaging.
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- OpenAlex ID
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Raw OpenAlex JSON
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https://openalex.org/W4385285701Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1371/journal.pone.0289144Digital Object Identifier
- Title
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Cost-effectiveness of repeat delayed imaging for spontaneous subarachnoid hemorrhageWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
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2023Year of publication
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2023-07-26Full publication date if available
- Authors
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Wenru Shang, Huajie Jin, Amisha Vastani, Asfand Baig Mirza, Benjamin Franklin Fisher, Neeraj Kalra, Ian Anderson, Ahilan Kailaya-VasanList of authors in order
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https://doi.org/10.1371/journal.pone.0289144Publisher landing page
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1371/journal.pone.0289144Direct OA link when available
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Subarachnoid hemorrhage, Medicine, SurgeryTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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