Could Phosphorous MR Spectroscopy Help Predict the Severity of Vasospasm? A Pilot Study Article Swipe
Malik Galijašević
,
Ruth Steiger
,
Stephanie Alice Treichl
,
Wing Man Ho
,
Stephanie Mangesius
,
Valentin Ladenhauf
,
Johannes Deeg
,
Leonhard Gruber
,
Miar Ouaret
,
Milovan Regodić
,
Lukas Lenhart
,
Bettina Pfausler
,
Astrid Grams
,
Ondra Petr
,
Claudius Thomé
,
Elke R. Gizewski
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/diagnostics14080841
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/diagnostics14080841
One of the main causes of the dismal prognosis in patients who survive the initial bleeding after aneurysmal subarachnoidal hemorrhage is the delayed cerebral ischaemia caused by vasospasm. Studies suggest that cerebral magnesium and pH may potentially play a role in the pathophysiology of this adverse event. Using phosphorous magnetic resonance spectrocopy (31P-MRS), we calculated the cerebral magnesium (Mg) and pH levels in 13 patients who suffered from aSAH. The values between the group that developed clinically significant vasospasm (n = 7) and the group that did not (n = 6) were compared. The results of this study show significantly lower cerebral Mg levels (p = 0.019) and higher pH levels (p < 0.001) in the cumulative group (all brain voxels together) in patients who developed clinically significant vasospasm. Further clinical studies on a larger group of carefully selected patients are needed in order to predict clinically significant vasospasm.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/diagnostics14080841
- https://www.mdpi.com/2075-4418/14/8/841/pdf?version=1713443186
- OA Status
- gold
- References
- 54
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4394914378
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4394914378Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/diagnostics14080841Digital Object Identifier
- Title
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Could Phosphorous MR Spectroscopy Help Predict the Severity of Vasospasm? A Pilot StudyWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-04-18Full publication date if available
- Authors
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Malik Galijašević, Ruth Steiger, Stephanie Alice Treichl, Wing Man Ho, Stephanie Mangesius, Valentin Ladenhauf, Johannes Deeg, Leonhard Gruber, Miar Ouaret, Milovan Regodić, Lukas Lenhart, Bettina Pfausler, Astrid Grams, Ondra Petr, Claudius Thomé, Elke R. GizewskiList of authors in order
- Landing page
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https://doi.org/10.3390/diagnostics14080841Publisher landing page
- PDF URL
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https://www.mdpi.com/2075-4418/14/8/841/pdf?version=1713443186Direct link to full text PDF
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://www.mdpi.com/2075-4418/14/8/841/pdf?version=1713443186Direct OA link when available
- Concepts
-
Vasospasm, Pathophysiology, Medicine, Internal medicine, Cerebral vasospasm, Neuronal damage, Magnetic resonance imaging, Anesthesia, Subarachnoid hemorrhage, Ischemia, Cardiology, RadiologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- References (count)
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54Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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