COVID-19: Recent Insight in Genomic Feature, Pathogenesis,Immunological Biomarkers, Treatment Options and Clinical Updates onSARS-CoV-2 Article Swipe
Rohitas Deshmukh
,
Ranjit K. Harwansh
,
Akash Garg
,
Sakshi Mishra
,
Rutvi Agrawal
,
Rajendra Jangde
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.2174/0113892029291098240129113500
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.2174/0113892029291098240129113500
SARS-CoV-2 is a highly contagious and transmissible viral infection that first emerged in 2019 and since then has sparked an epidemic of severe respiratory problems identified as “coronavirus disease 2019” (COVID-19) that causes a hazard to human life and safety. The virus developed mainly from bats. The current epidemic has presented a significant warning to life across the world by showing mutation. There are different tests available for testing Coronavirus, and RTPCR is the best, giving more accurate results, but it is also time-consuming. There are different options available for treating n-CoV-19, which include medications such as Remdesivir, corticosteroids, plasma therapy, Dexamethasone therapy, etc. The development of vaccines such as BNT126b2, ChAdOX1, mRNA-1273 and BBIBP-CorV has provided great relief in dealing with the virus as they decreased the mortality rate. BNT126b2 and ChAdOX1 are two n-CoV vaccines found to be most effective in controlling the spread of infection. In the future, nanotechnology-based vaccines and immune engineering techniques can be helpful for further research on Coronavirus and treatment of this deadly virus. The existing knowledge about the existence of SARS-- CoV-2, along with its variants, is summarized in this review. This review, based on recently published findings, presents the core genetics of COVID-19, including heritable characteristics, pathogenesis, immunological biomarkers, treatment options and clinical updates on the virus, along with patents.
Related Topics
Concepts
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
2019-20 coronavirus outbreak
Feature (linguistics)
Pathogenesis
Computational biology
Virology
Medicine
Sars virus
Biology
Immunology
Disease
Pathology
Infectious disease (medical specialty)
Philosophy
Linguistics
Outbreak
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.2174/0113892029291098240129113500
- OA Status
- green
- Cited By
- 5
- References
- 123
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4391614321
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4391614321Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.2174/0113892029291098240129113500Digital Object Identifier
- Title
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COVID-19: Recent Insight in Genomic Feature, Pathogenesis,Immunological Biomarkers, Treatment Options and Clinical Updates onSARS-CoV-2Work title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-02-07Full publication date if available
- Authors
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Rohitas Deshmukh, Ranjit K. Harwansh, Akash Garg, Sakshi Mishra, Rutvi Agrawal, Rajendra JangdeList of authors in order
- Landing page
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https://doi.org/10.2174/0113892029291098240129113500Publisher landing page
- Open access
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
- OA URL
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https://www.ncbi.nlm.nih.gov/pmc/articles/11092912Direct OA link when available
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Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), 2019-20 coronavirus outbreak, Feature (linguistics), Pathogenesis, Computational biology, Virology, Medicine, Sars virus, Biology, Immunology, Disease, Pathology, Infectious disease (medical specialty), Philosophy, Linguistics, OutbreakTop concepts (fields/topics) attached by OpenAlex
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5Total citation count in OpenAlex
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2025: 4, 2024: 1Per-year citation counts (last 5 years)
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123Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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