Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses Article Swipe
Federica Vecchio
,
Alexia Carré
,
Daniil Korenkov
,
Zhicheng Zhou
,
Paola S. Apaolaza
,
Soile Tuomela
,
Orlando Burgos‐Morales
,
Isaac Snowhite
,
Javier Perez-Hernandez
,
Barbara Brandao
,
Georgia Afonso
,
Clémentine Halliez
,
John S. Kaddis
,
Sally C. Kent
,
Maki Nakayama
,
Sarah J. Richardson
,
Joëlle Vinh
,
Yann Verdier
,
Jutta E. Laiho
,
Raphaël Scharfmann
,
Michele Solimena
,
Zuzana Mariničová
,
Élise Bismuth
,
Nadine Lucidarme
,
Janine Sanchez
,
Carmen Bustamante
,
L. Gómez
,
Søren Buus
,
Sylvaine You
,
Alberto Pugliese
,
Heikki Hyöty
,
Teresa Rodríguez-Calvo
,
Malin Flodström‐Tullberg
,
Roberto Mallone
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1126/sciadv.adl1122
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1126/sciadv.adl1122
Coxsackievirus B (CVB) infection of pancreatic β cells is associated with β cell autoimmunity and type 1 diabetes. We investigated how CVB affects human β cells and anti-CVB T cell responses. β cells were efficiently infected by CVB in vitro, down-regulated human leukocyte antigen (HLA) class I, and presented few, selected HLA-bound viral peptides. Circulating CD8 + T cells from CVB–seropositive individuals recognized a fraction of these peptides; only another subfraction was targeted by effector/memory T cells that expressed exhaustion marker PD-1. T cells recognizing a CVB epitope cross-reacted with β cell antigen GAD. Infected β cells, which formed filopodia to propagate infection, were more efficiently killed by CVB than by CVB-reactive T cells. Our in vitro and ex vivo data highlight limited CD8 + T cell responses to CVB, supporting the rationale for CVB vaccination trials for type 1 diabetes prevention. CD8 + T cells recognizing structural and nonstructural CVB epitopes provide biomarkers to differentially follow response to infection and vaccination.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1126/sciadv.adl1122
- https://www.science.org/doi/pdf/10.1126/sciadv.adl1122?download=true
- OA Status
- gold
- Cited By
- 14
- References
- 54
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4392528333
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4392528333Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1126/sciadv.adl1122Digital Object Identifier
- Title
-
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responsesWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-03-06Full publication date if available
- Authors
-
Federica Vecchio, Alexia Carré, Daniil Korenkov, Zhicheng Zhou, Paola S. Apaolaza, Soile Tuomela, Orlando Burgos‐Morales, Isaac Snowhite, Javier Perez-Hernandez, Barbara Brandao, Georgia Afonso, Clémentine Halliez, John S. Kaddis, Sally C. Kent, Maki Nakayama, Sarah J. Richardson, Joëlle Vinh, Yann Verdier, Jutta E. Laiho, Raphaël Scharfmann, Michele Solimena, Zuzana Mariničová, Élise Bismuth, Nadine Lucidarme, Janine Sanchez, Carmen Bustamante, L. Gómez, Søren Buus, Sylvaine You, Alberto Pugliese, Heikki Hyöty, Teresa Rodríguez-Calvo, Malin Flodström‐Tullberg, Roberto MalloneList of authors in order
- Landing page
-
https://doi.org/10.1126/sciadv.adl1122Publisher landing page
- PDF URL
-
https://www.science.org/doi/pdf/10.1126/sciadv.adl1122?download=trueDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.science.org/doi/pdf/10.1126/sciadv.adl1122?download=trueDirect OA link when available
- Concepts
-
Coxsackievirus, Virology, Enterovirus, CD8, Cell, Cytotoxic T cell, Biology, Virus, Medicine, Microbiology, Immunology, Immune system, Genetics, In vitroTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
14Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 6, 2024: 8Per-year citation counts (last 5 years)
- References (count)
-
54Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4392528333 |
|---|---|
| doi | https://doi.org/10.1126/sciadv.adl1122 |
| ids.doi | https://doi.org/10.1126/sciadv.adl1122 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/38446892 |
| ids.openalex | https://openalex.org/W4392528333 |
| fwci | 15.31880227 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D006801 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Humans |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D018414 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | CD8-Positive T-Lymphocytes |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D003922 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Diabetes Mellitus, Type 1 |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D050417 |
| mesh[3].is_major_topic | True |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Insulin-Secreting Cells |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D000906 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Antibodies |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D003384 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Coxsackievirus Infections |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D000939 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Epitopes |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D010455 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Peptides |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D000998 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Antiviral Agents |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D006801 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Humans |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D018414 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | CD8-Positive T-Lymphocytes |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D003922 |
| mesh[11].is_major_topic | True |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Diabetes Mellitus, Type 1 |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D050417 |
| mesh[12].is_major_topic | True |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Insulin-Secreting Cells |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D000906 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Antibodies |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D003384 |
| mesh[14].is_major_topic | True |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Coxsackievirus Infections |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D000939 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Epitopes |
| mesh[16].qualifier_ui | |
| mesh[16].descriptor_ui | D010455 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | |
| mesh[16].descriptor_name | Peptides |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D000998 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Antiviral Agents |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D006801 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Humans |
| mesh[19].qualifier_ui | |
| mesh[19].descriptor_ui | D018414 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | |
| mesh[19].descriptor_name | CD8-Positive T-Lymphocytes |
| mesh[20].qualifier_ui | |
| mesh[20].descriptor_ui | D003922 |
| mesh[20].is_major_topic | True |
| mesh[20].qualifier_name | |
| mesh[20].descriptor_name | Diabetes Mellitus, Type 1 |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D050417 |
| mesh[21].is_major_topic | True |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Insulin-Secreting Cells |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D000906 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Antibodies |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D003384 |
| mesh[23].is_major_topic | True |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Coxsackievirus Infections |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D000939 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Epitopes |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D010455 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Peptides |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D000998 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Antiviral Agents |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D006801 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Humans |
| mesh[28].qualifier_ui | |
| mesh[28].descriptor_ui | D018414 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | |
| mesh[28].descriptor_name | CD8-Positive T-Lymphocytes |
| mesh[29].qualifier_ui | |
| mesh[29].descriptor_ui | D003922 |
| mesh[29].is_major_topic | True |
| mesh[29].qualifier_name | |
| mesh[29].descriptor_name | Diabetes Mellitus, Type 1 |
| mesh[30].qualifier_ui | |
| mesh[30].descriptor_ui | D050417 |
| mesh[30].is_major_topic | True |
| mesh[30].qualifier_name | |
| mesh[30].descriptor_name | Insulin-Secreting Cells |
| mesh[31].qualifier_ui | |
| mesh[31].descriptor_ui | D000906 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | |
| mesh[31].descriptor_name | Antibodies |
| mesh[32].qualifier_ui | |
| mesh[32].descriptor_ui | D003384 |
| mesh[32].is_major_topic | True |
| mesh[32].qualifier_name | |
| mesh[32].descriptor_name | Coxsackievirus Infections |
| mesh[33].qualifier_ui | |
| mesh[33].descriptor_ui | D000939 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | |
| mesh[33].descriptor_name | Epitopes |
| mesh[34].qualifier_ui | |
| mesh[34].descriptor_ui | D010455 |
| mesh[34].is_major_topic | False |
| mesh[34].qualifier_name | |
| mesh[34].descriptor_name | Peptides |
| mesh[35].qualifier_ui | |
| mesh[35].descriptor_ui | D000998 |
| mesh[35].is_major_topic | False |
| mesh[35].qualifier_name | |
| mesh[35].descriptor_name | Antiviral Agents |
| mesh[36].qualifier_ui | |
| mesh[36].descriptor_ui | D006801 |
| mesh[36].is_major_topic | False |
| mesh[36].qualifier_name | |
| mesh[36].descriptor_name | Humans |
| mesh[37].qualifier_ui | |
| mesh[37].descriptor_ui | D018414 |
| mesh[37].is_major_topic | False |
| mesh[37].qualifier_name | |
| mesh[37].descriptor_name | CD8-Positive T-Lymphocytes |
| mesh[38].qualifier_ui | |
| mesh[38].descriptor_ui | D003922 |
| mesh[38].is_major_topic | True |
| mesh[38].qualifier_name | |
| mesh[38].descriptor_name | Diabetes Mellitus, Type 1 |
| mesh[39].qualifier_ui | |
| mesh[39].descriptor_ui | D050417 |
| mesh[39].is_major_topic | True |
| mesh[39].qualifier_name | |
| mesh[39].descriptor_name | Insulin-Secreting Cells |
| mesh[40].qualifier_ui | |
| mesh[40].descriptor_ui | D000906 |
| mesh[40].is_major_topic | False |
| mesh[40].qualifier_name | |
| mesh[40].descriptor_name | Antibodies |
| mesh[41].qualifier_ui | |
| mesh[41].descriptor_ui | D003384 |
| mesh[41].is_major_topic | True |
| mesh[41].qualifier_name | |
| mesh[41].descriptor_name | Coxsackievirus Infections |
| mesh[42].qualifier_ui | |
| mesh[42].descriptor_ui | D000939 |
| mesh[42].is_major_topic | False |
| mesh[42].qualifier_name | |
| mesh[42].descriptor_name | Epitopes |
| mesh[43].qualifier_ui | |
| mesh[43].descriptor_ui | D010455 |
| mesh[43].is_major_topic | False |
| mesh[43].qualifier_name | |
| mesh[43].descriptor_name | Peptides |
| mesh[44].qualifier_ui | |
| mesh[44].descriptor_ui | D000998 |
| mesh[44].is_major_topic | False |
| mesh[44].qualifier_name | |
| mesh[44].descriptor_name | Antiviral Agents |
| mesh[45].qualifier_ui | |
| mesh[45].descriptor_ui | D006801 |
| mesh[45].is_major_topic | False |
| mesh[45].qualifier_name | |
| mesh[45].descriptor_name | Humans |
| mesh[46].qualifier_ui | |
| mesh[46].descriptor_ui | D018414 |
| mesh[46].is_major_topic | False |
| mesh[46].qualifier_name | |
| mesh[46].descriptor_name | CD8-Positive T-Lymphocytes |
| mesh[47].qualifier_ui | |
| mesh[47].descriptor_ui | D003922 |
| mesh[47].is_major_topic | True |
| mesh[47].qualifier_name | |
| mesh[47].descriptor_name | Diabetes Mellitus, Type 1 |
| mesh[48].qualifier_ui | |
| mesh[48].descriptor_ui | D050417 |
| mesh[48].is_major_topic | True |
| mesh[48].qualifier_name | |
| mesh[48].descriptor_name | Insulin-Secreting Cells |
| mesh[49].qualifier_ui | |
| mesh[49].descriptor_ui | D000906 |
| mesh[49].is_major_topic | False |
| mesh[49].qualifier_name | |
| mesh[49].descriptor_name | Antibodies |
| type | article |
| title | Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses |
| biblio.issue | 10 |
| biblio.volume | 10 |
| biblio.last_page | eadl1122 |
| biblio.first_page | eadl1122 |
| topics[0].id | https://openalex.org/T11171 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9998999834060669 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1311 |
| topics[0].subfield.display_name | Genetics |
| topics[0].display_name | Diabetes and associated disorders |
| topics[1].id | https://openalex.org/T11725 |
| topics[1].field.id | https://openalex.org/fields/24 |
| topics[1].field.display_name | Immunology and Microbiology |
| topics[1].score | 0.9983000159263611 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2403 |
| topics[1].subfield.display_name | Immunology |
| topics[1].display_name | Immunodeficiency and Autoimmune Disorders |
| topics[2].id | https://openalex.org/T10118 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9979000091552734 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2725 |
| topics[2].subfield.display_name | Infectious Diseases |
| topics[2].display_name | SARS-CoV-2 and COVID-19 Research |
| is_xpac | False |
| apc_list.value | 4500 |
| apc_list.currency | USD |
| apc_list.value_usd | 4500 |
| apc_paid.value | 4500 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 4500 |
| concepts[0].id | https://openalex.org/C2779120600 |
| concepts[0].level | 4 |
| concepts[0].score | 0.7918635010719299 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q1138287 |
| concepts[0].display_name | Coxsackievirus |
| concepts[1].id | https://openalex.org/C159047783 |
| concepts[1].level | 1 |
| concepts[1].score | 0.6703758239746094 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q7215 |
| concepts[1].display_name | Virology |
| concepts[2].id | https://openalex.org/C2777888124 |
| concepts[2].level | 3 |
| concepts[2].score | 0.5185257196426392 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q519796 |
| concepts[2].display_name | Enterovirus |
| concepts[3].id | https://openalex.org/C167672396 |
| concepts[3].level | 3 |
| concepts[3].score | 0.5086206197738647 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q417800 |
| concepts[3].display_name | CD8 |
| concepts[4].id | https://openalex.org/C1491633281 |
| concepts[4].level | 2 |
| concepts[4].score | 0.5005691051483154 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q7868 |
| concepts[4].display_name | Cell |
| concepts[5].id | https://openalex.org/C154317977 |
| concepts[5].level | 3 |
| concepts[5].score | 0.43577373027801514 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q376266 |
| concepts[5].display_name | Cytotoxic T cell |
| concepts[6].id | https://openalex.org/C86803240 |
| concepts[6].level | 0 |
| concepts[6].score | 0.4236252009868622 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[6].display_name | Biology |
| concepts[7].id | https://openalex.org/C2522874641 |
| concepts[7].level | 2 |
| concepts[7].score | 0.3507707417011261 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q808 |
| concepts[7].display_name | Virus |
| concepts[8].id | https://openalex.org/C71924100 |
| concepts[8].level | 0 |
| concepts[8].score | 0.33995944261550903 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[8].display_name | Medicine |
| concepts[9].id | https://openalex.org/C89423630 |
| concepts[9].level | 1 |
| concepts[9].score | 0.3370038568973541 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q7193 |
| concepts[9].display_name | Microbiology |
| concepts[10].id | https://openalex.org/C203014093 |
| concepts[10].level | 1 |
| concepts[10].score | 0.3362046480178833 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q101929 |
| concepts[10].display_name | Immunology |
| concepts[11].id | https://openalex.org/C8891405 |
| concepts[11].level | 2 |
| concepts[11].score | 0.2108001410961151 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q1059 |
| concepts[11].display_name | Immune system |
| concepts[12].id | https://openalex.org/C54355233 |
| concepts[12].level | 1 |
| concepts[12].score | 0.07741427421569824 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[12].display_name | Genetics |
| concepts[13].id | https://openalex.org/C202751555 |
| concepts[13].level | 2 |
| concepts[13].score | 0.0 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q221681 |
| concepts[13].display_name | In vitro |
| keywords[0].id | https://openalex.org/keywords/coxsackievirus |
| keywords[0].score | 0.7918635010719299 |
| keywords[0].display_name | Coxsackievirus |
| keywords[1].id | https://openalex.org/keywords/virology |
| keywords[1].score | 0.6703758239746094 |
| keywords[1].display_name | Virology |
| keywords[2].id | https://openalex.org/keywords/enterovirus |
| keywords[2].score | 0.5185257196426392 |
| keywords[2].display_name | Enterovirus |
| keywords[3].id | https://openalex.org/keywords/cd8 |
| keywords[3].score | 0.5086206197738647 |
| keywords[3].display_name | CD8 |
| keywords[4].id | https://openalex.org/keywords/cell |
| keywords[4].score | 0.5005691051483154 |
| keywords[4].display_name | Cell |
| keywords[5].id | https://openalex.org/keywords/cytotoxic-t-cell |
| keywords[5].score | 0.43577373027801514 |
| keywords[5].display_name | Cytotoxic T cell |
| keywords[6].id | https://openalex.org/keywords/biology |
| keywords[6].score | 0.4236252009868622 |
| keywords[6].display_name | Biology |
| keywords[7].id | https://openalex.org/keywords/virus |
| keywords[7].score | 0.3507707417011261 |
| keywords[7].display_name | Virus |
| keywords[8].id | https://openalex.org/keywords/medicine |
| keywords[8].score | 0.33995944261550903 |
| keywords[8].display_name | Medicine |
| keywords[9].id | https://openalex.org/keywords/microbiology |
| keywords[9].score | 0.3370038568973541 |
| keywords[9].display_name | Microbiology |
| keywords[10].id | https://openalex.org/keywords/immunology |
| keywords[10].score | 0.3362046480178833 |
| keywords[10].display_name | Immunology |
| keywords[11].id | https://openalex.org/keywords/immune-system |
| keywords[11].score | 0.2108001410961151 |
| keywords[11].display_name | Immune system |
| keywords[12].id | https://openalex.org/keywords/genetics |
| keywords[12].score | 0.07741427421569824 |
| keywords[12].display_name | Genetics |
| language | en |
| locations[0].id | doi:10.1126/sciadv.adl1122 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2737427234 |
| locations[0].source.issn | 2375-2548 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2375-2548 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Science Advances |
| locations[0].source.host_organization | https://openalex.org/P4310315823 |
| locations[0].source.host_organization_name | American Association for the Advancement of Science |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310315823 |
| locations[0].license | |
| locations[0].pdf_url | https://www.science.org/doi/pdf/10.1126/sciadv.adl1122?download=true |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Science Advances |
| locations[0].landing_page_url | https://doi.org/10.1126/sciadv.adl1122 |
| locations[1].id | pmid:38446892 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Science advances |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/38446892 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:10917340 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | cc-by |
| locations[2].pdf_url | https://pmc.ncbi.nlm.nih.gov/articles/PMC10917340/pdf/sciadv.adl1122.pdf |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/cc-by |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Sci Adv |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/10917340 |
| locations[3].id | pmh:oai:ore.exeter.ac.uk:10871/137022 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S4306401998 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | Open Research Exeter (University of Exeter) |
| locations[3].source.host_organization | https://openalex.org/I23923803 |
| locations[3].source.host_organization_name | University of Exeter |
| locations[3].source.host_organization_lineage | https://openalex.org/I23923803 |
| locations[3].license | cc-by |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Article |
| locations[3].license_id | https://openalex.org/licenses/cc-by |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | |
| locations[3].landing_page_url | http://hdl.handle.net/10871/137022 |
| locations[4].id | pmh:oai:HAL:hal-04542472v1 |
| locations[4].is_oa | True |
| locations[4].source.id | https://openalex.org/S4306402512 |
| locations[4].source.issn | |
| locations[4].source.type | repository |
| locations[4].source.is_oa | False |
| locations[4].source.issn_l | |
| locations[4].source.is_core | False |
| locations[4].source.is_in_doaj | False |
| locations[4].source.display_name | HAL (Le Centre pour la Communication Scientifique Directe) |
| locations[4].source.host_organization | https://openalex.org/I1294671590 |
| locations[4].source.host_organization_name | Centre National de la Recherche Scientifique |
| locations[4].source.host_organization_lineage | https://openalex.org/I1294671590 |
| locations[4].license | other-oa |
| locations[4].pdf_url | |
| locations[4].version | submittedVersion |
| locations[4].raw_type | Journal articles |
| locations[4].license_id | https://openalex.org/licenses/other-oa |
| locations[4].is_accepted | False |
| locations[4].is_published | False |
| locations[4].raw_source_name | Science Advances , 2024, 10 (10), pp.eadl1122. ⟨10.1126/sciadv.adl1122⟩ |
| locations[4].landing_page_url | https://hal.science/hal-04542472 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5086228773 |
| authorships[0].author.orcid | https://orcid.org/0000-0003-4607-8818 |
| authorships[0].author.display_name | Federica Vecchio |
| authorships[0].countries | FR |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[0].affiliations[0].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[0].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[0].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[0].institutions[0].type | government |
| authorships[0].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[0].institutions[0].country_code | FR |
| authorships[0].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[0].institutions[1].id | https://openalex.org/I154526488 |
| authorships[0].institutions[1].ror | https://ror.org/02vjkv261 |
| authorships[0].institutions[1].type | government |
| authorships[0].institutions[1].lineage | https://openalex.org/I154526488 |
| authorships[0].institutions[1].country_code | FR |
| authorships[0].institutions[1].display_name | Inserm |
| authorships[0].institutions[2].id | https://openalex.org/I4210141964 |
| authorships[0].institutions[2].ror | https://ror.org/051sk4035 |
| authorships[0].institutions[2].type | facility |
| authorships[0].institutions[2].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[0].institutions[2].country_code | FR |
| authorships[0].institutions[2].display_name | Institut Cochin |
| authorships[0].institutions[3].id | https://openalex.org/I204730241 |
| authorships[0].institutions[3].ror | https://ror.org/05f82e368 |
| authorships[0].institutions[3].type | education |
| authorships[0].institutions[3].lineage | https://openalex.org/I204730241 |
| authorships[0].institutions[3].country_code | FR |
| authorships[0].institutions[3].display_name | Université Paris Cité |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Federica Vecchio |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[1].author.id | https://openalex.org/A5077733570 |
| authorships[1].author.orcid | https://orcid.org/0000-0001-8144-7194 |
| authorships[1].author.display_name | Alexia Carré |
| authorships[1].countries | FR |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[1].affiliations[0].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[1].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[1].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[1].institutions[0].type | government |
| authorships[1].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[1].institutions[0].country_code | FR |
| authorships[1].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[1].institutions[1].id | https://openalex.org/I154526488 |
| authorships[1].institutions[1].ror | https://ror.org/02vjkv261 |
| authorships[1].institutions[1].type | government |
| authorships[1].institutions[1].lineage | https://openalex.org/I154526488 |
| authorships[1].institutions[1].country_code | FR |
| authorships[1].institutions[1].display_name | Inserm |
| authorships[1].institutions[2].id | https://openalex.org/I4210141964 |
| authorships[1].institutions[2].ror | https://ror.org/051sk4035 |
| authorships[1].institutions[2].type | facility |
| authorships[1].institutions[2].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[1].institutions[2].country_code | FR |
| authorships[1].institutions[2].display_name | Institut Cochin |
| authorships[1].institutions[3].id | https://openalex.org/I204730241 |
| authorships[1].institutions[3].ror | https://ror.org/05f82e368 |
| authorships[1].institutions[3].type | education |
| authorships[1].institutions[3].lineage | https://openalex.org/I204730241 |
| authorships[1].institutions[3].country_code | FR |
| authorships[1].institutions[3].display_name | Université Paris Cité |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Alexia Carré |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[2].author.id | https://openalex.org/A5044515158 |
| authorships[2].author.orcid | https://orcid.org/0000-0001-8321-778X |
| authorships[2].author.display_name | Daniil Korenkov |
| authorships[2].countries | FR |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[2].affiliations[0].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[2].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[2].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[2].institutions[0].type | government |
| authorships[2].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[2].institutions[0].country_code | FR |
| authorships[2].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[2].institutions[1].id | https://openalex.org/I154526488 |
| authorships[2].institutions[1].ror | https://ror.org/02vjkv261 |
| authorships[2].institutions[1].type | government |
| authorships[2].institutions[1].lineage | https://openalex.org/I154526488 |
| authorships[2].institutions[1].country_code | FR |
| authorships[2].institutions[1].display_name | Inserm |
| authorships[2].institutions[2].id | https://openalex.org/I4210141964 |
| authorships[2].institutions[2].ror | https://ror.org/051sk4035 |
| authorships[2].institutions[2].type | facility |
| authorships[2].institutions[2].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[2].institutions[2].country_code | FR |
| authorships[2].institutions[2].display_name | Institut Cochin |
| authorships[2].institutions[3].id | https://openalex.org/I204730241 |
| authorships[2].institutions[3].ror | https://ror.org/05f82e368 |
| authorships[2].institutions[3].type | education |
| authorships[2].institutions[3].lineage | https://openalex.org/I204730241 |
| authorships[2].institutions[3].country_code | FR |
| authorships[2].institutions[3].display_name | Université Paris Cité |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Daniil Korenkov |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[3].author.id | https://openalex.org/A5050828277 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-9137-7951 |
| authorships[3].author.display_name | Zhicheng Zhou |
| authorships[3].countries | FR |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[3].affiliations[0].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[3].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[3].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[3].institutions[0].type | government |
| authorships[3].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[3].institutions[0].country_code | FR |
| authorships[3].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[3].institutions[1].id | https://openalex.org/I154526488 |
| authorships[3].institutions[1].ror | https://ror.org/02vjkv261 |
| authorships[3].institutions[1].type | government |
| authorships[3].institutions[1].lineage | https://openalex.org/I154526488 |
| authorships[3].institutions[1].country_code | FR |
| authorships[3].institutions[1].display_name | Inserm |
| authorships[3].institutions[2].id | https://openalex.org/I4210141964 |
| authorships[3].institutions[2].ror | https://ror.org/051sk4035 |
| authorships[3].institutions[2].type | facility |
| authorships[3].institutions[2].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[3].institutions[2].country_code | FR |
| authorships[3].institutions[2].display_name | Institut Cochin |
| authorships[3].institutions[3].id | https://openalex.org/I204730241 |
| authorships[3].institutions[3].ror | https://ror.org/05f82e368 |
| authorships[3].institutions[3].type | education |
| authorships[3].institutions[3].lineage | https://openalex.org/I204730241 |
| authorships[3].institutions[3].country_code | FR |
| authorships[3].institutions[3].display_name | Université Paris Cité |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Zhicheng Zhou |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[4].author.id | https://openalex.org/A5034366409 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-7550-054X |
| authorships[4].author.display_name | Paola S. Apaolaza |
| authorships[4].countries | DE |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210152419, https://openalex.org/I4210160326, https://openalex.org/I44260953 |
| authorships[4].affiliations[0].raw_affiliation_string | German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany. |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I3018134672 |
| authorships[4].affiliations[1].raw_affiliation_string | Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany. |
| authorships[4].institutions[0].id | https://openalex.org/I4210152419 |
| authorships[4].institutions[0].ror | https://ror.org/04ews3245 |
| authorships[4].institutions[0].type | facility |
| authorships[4].institutions[0].lineage | https://openalex.org/I315704651, https://openalex.org/I4210152419, https://openalex.org/I44260953 |
| authorships[4].institutions[0].country_code | DE |
| authorships[4].institutions[0].display_name | Deutsches Diabetes-Zentrum e.V. |
| authorships[4].institutions[1].id | https://openalex.org/I4210160326 |
| authorships[4].institutions[1].ror | https://ror.org/04qq88z54 |
| authorships[4].institutions[1].type | facility |
| authorships[4].institutions[1].lineage | https://openalex.org/I4210160326, https://openalex.org/I4411590659 |
| authorships[4].institutions[1].country_code | DE |
| authorships[4].institutions[1].display_name | German Center for Diabetes Research |
| authorships[4].institutions[2].id | https://openalex.org/I44260953 |
| authorships[4].institutions[2].ror | https://ror.org/024z2rq82 |
| authorships[4].institutions[2].type | education |
| authorships[4].institutions[2].lineage | https://openalex.org/I44260953 |
| authorships[4].institutions[2].country_code | DE |
| authorships[4].institutions[2].display_name | Heinrich Heine University Düsseldorf |
| authorships[4].institutions[3].id | https://openalex.org/I3018134672 |
| authorships[4].institutions[3].ror | https://ror.org/00cfam450 |
| authorships[4].institutions[3].type | facility |
| authorships[4].institutions[3].lineage | https://openalex.org/I1305996414, https://openalex.org/I3018134672 |
| authorships[4].institutions[3].country_code | DE |
| authorships[4].institutions[3].display_name | Helmholtz Zentrum München |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Paola Apaolaza |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany. |
| authorships[5].author.id | https://openalex.org/A5033423065 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Soile Tuomela |
| authorships[5].affiliations[0].raw_affiliation_string | center for infectious Medicine, de-partment of Medicine huddinge, Karolinska institutet, Karolinska University hospi-tal huddinge, Stockholm, Sweden. |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Soile Tuomela |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | center for infectious Medicine, de-partment of Medicine huddinge, Karolinska institutet, Karolinska University hospi-tal huddinge, Stockholm, Sweden. |
| authorships[6].author.id | https://openalex.org/A5052197865 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-5086-2675 |
| authorships[6].author.display_name | Orlando Burgos‐Morales |
| authorships[6].countries | FR |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[6].affiliations[0].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[6].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[6].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[6].institutions[0].type | government |
| authorships[6].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[6].institutions[0].country_code | FR |
| authorships[6].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[6].institutions[1].id | https://openalex.org/I154526488 |
| authorships[6].institutions[1].ror | https://ror.org/02vjkv261 |
| authorships[6].institutions[1].type | government |
| authorships[6].institutions[1].lineage | https://openalex.org/I154526488 |
| authorships[6].institutions[1].country_code | FR |
| authorships[6].institutions[1].display_name | Inserm |
| authorships[6].institutions[2].id | https://openalex.org/I4210141964 |
| authorships[6].institutions[2].ror | https://ror.org/051sk4035 |
| authorships[6].institutions[2].type | facility |
| authorships[6].institutions[2].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[6].institutions[2].country_code | FR |
| authorships[6].institutions[2].display_name | Institut Cochin |
| authorships[6].institutions[3].id | https://openalex.org/I204730241 |
| authorships[6].institutions[3].ror | https://ror.org/05f82e368 |
| authorships[6].institutions[3].type | education |
| authorships[6].institutions[3].lineage | https://openalex.org/I204730241 |
| authorships[6].institutions[3].country_code | FR |
| authorships[6].institutions[3].display_name | Université Paris Cité |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Orlando Burgos-Morales |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[7].author.id | https://openalex.org/A5029395333 |
| authorships[7].author.orcid | https://orcid.org/0009-0008-9387-0318 |
| authorships[7].author.display_name | Isaac Snowhite |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I4210110459, https://openalex.org/I4387156432 |
| authorships[7].affiliations[0].raw_affiliation_string | department of diabetes immunology, Arthur Riggs diabetes and Metabolism Research institute, Beckman Research institute, city of hope, duarte, cA, USA. |
| authorships[7].affiliations[1].institution_ids | https://openalex.org/I145608581 |
| authorships[7].affiliations[1].raw_affiliation_string | diabetes Research institute, leonard Miller School of Medicine, University of Miami, Miami, Fl, USA. |
| authorships[7].institutions[0].id | https://openalex.org/I4387156432 |
| authorships[7].institutions[0].ror | https://ror.org/05fazth07 |
| authorships[7].institutions[0].type | facility |
| authorships[7].institutions[0].lineage | https://openalex.org/I1301076528, https://openalex.org/I4387156432 |
| authorships[7].institutions[0].country_code | |
| authorships[7].institutions[0].display_name | Beckman Research Institute |
| authorships[7].institutions[1].id | https://openalex.org/I4210110459 |
| authorships[7].institutions[1].ror | https://ror.org/01z1vct10 |
| authorships[7].institutions[1].type | healthcare |
| authorships[7].institutions[1].lineage | https://openalex.org/I1301076528, https://openalex.org/I4210110459 |
| authorships[7].institutions[1].country_code | US |
| authorships[7].institutions[1].display_name | City of Hope |
| authorships[7].institutions[2].id | https://openalex.org/I145608581 |
| authorships[7].institutions[2].ror | https://ror.org/02dgjyy92 |
| authorships[7].institutions[2].type | education |
| authorships[7].institutions[2].lineage | https://openalex.org/I145608581 |
| authorships[7].institutions[2].country_code | US |
| authorships[7].institutions[2].display_name | University of Miami |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Isaac Snowhite |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | department of diabetes immunology, Arthur Riggs diabetes and Metabolism Research institute, Beckman Research institute, city of hope, duarte, cA, USA., diabetes Research institute, leonard Miller School of Medicine, University of Miami, Miami, Fl, USA. |
| authorships[8].author.id | https://openalex.org/A5068231110 |
| authorships[8].author.orcid | https://orcid.org/0000-0001-9712-2917 |
| authorships[8].author.display_name | Javier Perez-Hernandez |
| authorships[8].countries | FR |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[8].affiliations[0].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[8].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[8].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[8].institutions[0].type | government |
| authorships[8].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[8].institutions[0].country_code | FR |
| authorships[8].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[8].institutions[1].id | https://openalex.org/I154526488 |
| authorships[8].institutions[1].ror | https://ror.org/02vjkv261 |
| authorships[8].institutions[1].type | government |
| authorships[8].institutions[1].lineage | https://openalex.org/I154526488 |
| authorships[8].institutions[1].country_code | FR |
| authorships[8].institutions[1].display_name | Inserm |
| authorships[8].institutions[2].id | https://openalex.org/I4210141964 |
| authorships[8].institutions[2].ror | https://ror.org/051sk4035 |
| authorships[8].institutions[2].type | facility |
| authorships[8].institutions[2].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[8].institutions[2].country_code | FR |
| authorships[8].institutions[2].display_name | Institut Cochin |
| authorships[8].institutions[3].id | https://openalex.org/I204730241 |
| authorships[8].institutions[3].ror | https://ror.org/05f82e368 |
| authorships[8].institutions[3].type | education |
| authorships[8].institutions[3].lineage | https://openalex.org/I204730241 |
| authorships[8].institutions[3].country_code | FR |
| authorships[8].institutions[3].display_name | Université Paris Cité |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Javier Perez-Hernandez |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[9].author.id | https://openalex.org/A5018776382 |
| authorships[9].author.orcid | https://orcid.org/0009-0008-0128-0100 |
| authorships[9].author.display_name | Barbara Brandao |
| authorships[9].countries | FR |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[9].affiliations[0].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[9].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[9].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[9].institutions[0].type | government |
| authorships[9].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[9].institutions[0].country_code | FR |
| authorships[9].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[9].institutions[1].id | https://openalex.org/I154526488 |
| authorships[9].institutions[1].ror | https://ror.org/02vjkv261 |
| authorships[9].institutions[1].type | government |
| authorships[9].institutions[1].lineage | https://openalex.org/I154526488 |
| authorships[9].institutions[1].country_code | FR |
| authorships[9].institutions[1].display_name | Inserm |
| authorships[9].institutions[2].id | https://openalex.org/I4210141964 |
| authorships[9].institutions[2].ror | https://ror.org/051sk4035 |
| authorships[9].institutions[2].type | facility |
| authorships[9].institutions[2].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[9].institutions[2].country_code | FR |
| authorships[9].institutions[2].display_name | Institut Cochin |
| authorships[9].institutions[3].id | https://openalex.org/I204730241 |
| authorships[9].institutions[3].ror | https://ror.org/05f82e368 |
| authorships[9].institutions[3].type | education |
| authorships[9].institutions[3].lineage | https://openalex.org/I204730241 |
| authorships[9].institutions[3].country_code | FR |
| authorships[9].institutions[3].display_name | Université Paris Cité |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Barbara Brandao |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[10].author.id | https://openalex.org/A5044342048 |
| authorships[10].author.orcid | https://orcid.org/0000-0003-3759-7317 |
| authorships[10].author.display_name | Georgia Afonso |
| authorships[10].countries | FR |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[10].affiliations[0].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[10].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[10].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[10].institutions[0].type | government |
| authorships[10].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[10].institutions[0].country_code | FR |
| authorships[10].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[10].institutions[1].id | https://openalex.org/I154526488 |
| authorships[10].institutions[1].ror | https://ror.org/02vjkv261 |
| authorships[10].institutions[1].type | government |
| authorships[10].institutions[1].lineage | https://openalex.org/I154526488 |
| authorships[10].institutions[1].country_code | FR |
| authorships[10].institutions[1].display_name | Inserm |
| authorships[10].institutions[2].id | https://openalex.org/I4210141964 |
| authorships[10].institutions[2].ror | https://ror.org/051sk4035 |
| authorships[10].institutions[2].type | facility |
| authorships[10].institutions[2].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[10].institutions[2].country_code | FR |
| authorships[10].institutions[2].display_name | Institut Cochin |
| authorships[10].institutions[3].id | https://openalex.org/I204730241 |
| authorships[10].institutions[3].ror | https://ror.org/05f82e368 |
| authorships[10].institutions[3].type | education |
| authorships[10].institutions[3].lineage | https://openalex.org/I204730241 |
| authorships[10].institutions[3].country_code | FR |
| authorships[10].institutions[3].display_name | Université Paris Cité |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Georgia Afonso |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[11].author.id | https://openalex.org/A5030662576 |
| authorships[11].author.orcid | https://orcid.org/0000-0002-5683-515X |
| authorships[11].author.display_name | Clémentine Halliez |
| authorships[11].countries | FR |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I4210092774, https://openalex.org/I4210097159 |
| authorships[11].affiliations[0].raw_affiliation_string | Assistance Publique Hôpitaux de Paris, Service de Diabétologie et Immunologie Clinique, Cochin Hospital, Paris, France. |
| authorships[11].affiliations[1].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[11].affiliations[1].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[11].institutions[0].id | https://openalex.org/I4210097159 |
| authorships[11].institutions[0].ror | https://ror.org/00pg5jh14 |
| authorships[11].institutions[0].type | healthcare |
| authorships[11].institutions[0].lineage | https://openalex.org/I4210097159 |
| authorships[11].institutions[0].country_code | FR |
| authorships[11].institutions[0].display_name | Assistance Publique – Hôpitaux de Paris |
| authorships[11].institutions[1].id | https://openalex.org/I1294671590 |
| authorships[11].institutions[1].ror | https://ror.org/02feahw73 |
| authorships[11].institutions[1].type | government |
| authorships[11].institutions[1].lineage | https://openalex.org/I1294671590 |
| authorships[11].institutions[1].country_code | FR |
| authorships[11].institutions[1].display_name | Centre National de la Recherche Scientifique |
| authorships[11].institutions[2].id | https://openalex.org/I4210092774 |
| authorships[11].institutions[2].ror | https://ror.org/00ph8tk69 |
| authorships[11].institutions[2].type | healthcare |
| authorships[11].institutions[2].lineage | https://openalex.org/I4210092774, https://openalex.org/I4210097159, https://openalex.org/I4210124464 |
| authorships[11].institutions[2].country_code | FR |
| authorships[11].institutions[2].display_name | Hôpital Cochin |
| authorships[11].institutions[3].id | https://openalex.org/I154526488 |
| authorships[11].institutions[3].ror | https://ror.org/02vjkv261 |
| authorships[11].institutions[3].type | government |
| authorships[11].institutions[3].lineage | https://openalex.org/I154526488 |
| authorships[11].institutions[3].country_code | FR |
| authorships[11].institutions[3].display_name | Inserm |
| authorships[11].institutions[4].id | https://openalex.org/I4210141964 |
| authorships[11].institutions[4].ror | https://ror.org/051sk4035 |
| authorships[11].institutions[4].type | facility |
| authorships[11].institutions[4].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[11].institutions[4].country_code | FR |
| authorships[11].institutions[4].display_name | Institut Cochin |
| authorships[11].institutions[5].id | https://openalex.org/I204730241 |
| authorships[11].institutions[5].ror | https://ror.org/05f82e368 |
| authorships[11].institutions[5].type | education |
| authorships[11].institutions[5].lineage | https://openalex.org/I204730241 |
| authorships[11].institutions[5].country_code | FR |
| authorships[11].institutions[5].display_name | Université Paris Cité |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Clémentine Halliez |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | Assistance Publique Hôpitaux de Paris, Service de Diabétologie et Immunologie Clinique, Cochin Hospital, Paris, France., Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[12].author.id | https://openalex.org/A5082225007 |
| authorships[12].author.orcid | https://orcid.org/0000-0002-6752-7670 |
| authorships[12].author.display_name | John S. Kaddis |
| authorships[12].countries | US |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I4210110459, https://openalex.org/I4387156432 |
| authorships[12].affiliations[0].raw_affiliation_string | Department of Diabetes and Cancer Discovery Science, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA. |
| authorships[12].affiliations[1].institution_ids | https://openalex.org/I4210110459, https://openalex.org/I4387156432 |
| authorships[12].affiliations[1].raw_affiliation_string | department of diabetes and cancer discovery Science, Arthur Riggs dia-betes and Metabolism Research institute, Beckman Research institute, city of hope, duarte, cA, USA. |
| authorships[12].institutions[0].id | https://openalex.org/I4387156432 |
| authorships[12].institutions[0].ror | https://ror.org/05fazth07 |
| authorships[12].institutions[0].type | facility |
| authorships[12].institutions[0].lineage | https://openalex.org/I1301076528, https://openalex.org/I4387156432 |
| authorships[12].institutions[0].country_code | |
| authorships[12].institutions[0].display_name | Beckman Research Institute |
| authorships[12].institutions[1].id | https://openalex.org/I4210110459 |
| authorships[12].institutions[1].ror | https://ror.org/01z1vct10 |
| authorships[12].institutions[1].type | healthcare |
| authorships[12].institutions[1].lineage | https://openalex.org/I1301076528, https://openalex.org/I4210110459 |
| authorships[12].institutions[1].country_code | US |
| authorships[12].institutions[1].display_name | City of Hope |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | John Kaddis |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | Department of Diabetes and Cancer Discovery Science, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., department of diabetes and cancer discovery Science, Arthur Riggs dia-betes and Metabolism Research institute, Beckman Research institute, city of hope, duarte, cA, USA. |
| authorships[13].author.id | https://openalex.org/A5049865612 |
| authorships[13].author.orcid | https://orcid.org/0000-0002-1543-8086 |
| authorships[13].author.display_name | Sally C. Kent |
| authorships[13].countries | US |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I166722992 |
| authorships[13].affiliations[0].raw_affiliation_string | diabetes center of excellence, department of Medicine, University of Massachusetts Medical chan School, Worcester, MA, USA. |
| authorships[13].institutions[0].id | https://openalex.org/I166722992 |
| authorships[13].institutions[0].ror | https://ror.org/0464eyp60 |
| authorships[13].institutions[0].type | education |
| authorships[13].institutions[0].lineage | https://openalex.org/I166722992 |
| authorships[13].institutions[0].country_code | US |
| authorships[13].institutions[0].display_name | University of Massachusetts Chan Medical School |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | Sally C. Kent |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | diabetes center of excellence, department of Medicine, University of Massachusetts Medical chan School, Worcester, MA, USA. |
| authorships[14].author.id | https://openalex.org/A5019794250 |
| authorships[14].author.orcid | https://orcid.org/0000-0002-0009-3687 |
| authorships[14].author.display_name | Maki Nakayama |
| authorships[14].countries | US |
| authorships[14].affiliations[0].institution_ids | https://openalex.org/I921990950 |
| authorships[14].affiliations[0].raw_affiliation_string | Barbara davis center for diabetes, University of colorado School of Medicine, Aurora, cO, USA. |
| authorships[14].institutions[0].id | https://openalex.org/I921990950 |
| authorships[14].institutions[0].ror | https://ror.org/02hh7en24 |
| authorships[14].institutions[0].type | education |
| authorships[14].institutions[0].lineage | https://openalex.org/I921990950 |
| authorships[14].institutions[0].country_code | US |
| authorships[14].institutions[0].display_name | University of Colorado Denver |
| authorships[14].author_position | middle |
| authorships[14].raw_author_name | Maki Nakayama |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | Barbara davis center for diabetes, University of colorado School of Medicine, Aurora, cO, USA. |
| authorships[15].author.id | https://openalex.org/A5058034008 |
| authorships[15].author.orcid | https://orcid.org/0000-0002-1160-6062 |
| authorships[15].author.display_name | Sarah J. Richardson |
| authorships[15].countries | GB |
| authorships[15].affiliations[0].raw_affiliation_string | islet Biology exeter (iBex), exeter |
| authorships[15].affiliations[1].institution_ids | https://openalex.org/I23923803 |
| authorships[15].affiliations[1].raw_affiliation_string | Islet Biology Exeter (IBEx), Exeter Centre of Excellence for Diabetes Research (EXCEED), Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK. |
| authorships[15].institutions[0].id | https://openalex.org/I23923803 |
| authorships[15].institutions[0].ror | https://ror.org/03yghzc09 |
| authorships[15].institutions[0].type | education |
| authorships[15].institutions[0].lineage | https://openalex.org/I23923803 |
| authorships[15].institutions[0].country_code | GB |
| authorships[15].institutions[0].display_name | University of Exeter |
| authorships[15].author_position | middle |
| authorships[15].raw_author_name | Sarah J. Richardson |
| authorships[15].is_corresponding | False |
| authorships[15].raw_affiliation_strings | Islet Biology Exeter (IBEx), Exeter Centre of Excellence for Diabetes Research (EXCEED), Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK., islet Biology exeter (iBex), exeter |
| authorships[16].author.id | https://openalex.org/A5014468236 |
| authorships[16].author.orcid | https://orcid.org/0000-0001-7184-2668 |
| authorships[16].author.display_name | Joëlle Vinh |
| authorships[16].countries | FR |
| authorships[16].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I2746051580, https://openalex.org/I98910050 |
| authorships[16].affiliations[0].raw_affiliation_string | ESPCI Paris, PSL University, Spectrométrie de Masse Biologique et Protéomique, CNRS UMR8249, Paris, France. |
| authorships[16].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[16].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[16].institutions[0].type | government |
| authorships[16].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[16].institutions[0].country_code | FR |
| authorships[16].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[16].institutions[1].id | https://openalex.org/I98910050 |
| authorships[16].institutions[1].ror | https://ror.org/03zx86w41 |
| authorships[16].institutions[1].type | education |
| authorships[16].institutions[1].lineage | https://openalex.org/I190752583, https://openalex.org/I2746051580, https://openalex.org/I98910050 |
| authorships[16].institutions[1].country_code | FR |
| authorships[16].institutions[1].display_name | ESPCI Paris |
| authorships[16].institutions[2].id | https://openalex.org/I2746051580 |
| authorships[16].institutions[2].ror | https://ror.org/013cjyk83 |
| authorships[16].institutions[2].type | education |
| authorships[16].institutions[2].lineage | https://openalex.org/I2746051580 |
| authorships[16].institutions[2].country_code | FR |
| authorships[16].institutions[2].display_name | Université Paris Sciences et Lettres |
| authorships[16].author_position | middle |
| authorships[16].raw_author_name | Joelle Vinh |
| authorships[16].is_corresponding | False |
| authorships[16].raw_affiliation_strings | ESPCI Paris, PSL University, Spectrométrie de Masse Biologique et Protéomique, CNRS UMR8249, Paris, France. |
| authorships[17].author.id | https://openalex.org/A5027032373 |
| authorships[17].author.orcid | https://orcid.org/0000-0002-3319-0053 |
| authorships[17].author.display_name | Yann Verdier |
| authorships[17].countries | FR |
| authorships[17].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I2746051580, https://openalex.org/I98910050 |
| authorships[17].affiliations[0].raw_affiliation_string | ESPCI Paris, PSL University, Spectrométrie de Masse Biologique et Protéomique, CNRS UMR8249, Paris, France. |
| authorships[17].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[17].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[17].institutions[0].type | government |
| authorships[17].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[17].institutions[0].country_code | FR |
| authorships[17].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[17].institutions[1].id | https://openalex.org/I98910050 |
| authorships[17].institutions[1].ror | https://ror.org/03zx86w41 |
| authorships[17].institutions[1].type | education |
| authorships[17].institutions[1].lineage | https://openalex.org/I190752583, https://openalex.org/I2746051580, https://openalex.org/I98910050 |
| authorships[17].institutions[1].country_code | FR |
| authorships[17].institutions[1].display_name | ESPCI Paris |
| authorships[17].institutions[2].id | https://openalex.org/I2746051580 |
| authorships[17].institutions[2].ror | https://ror.org/013cjyk83 |
| authorships[17].institutions[2].type | education |
| authorships[17].institutions[2].lineage | https://openalex.org/I2746051580 |
| authorships[17].institutions[2].country_code | FR |
| authorships[17].institutions[2].display_name | Université Paris Sciences et Lettres |
| authorships[17].author_position | middle |
| authorships[17].raw_author_name | Yann Verdier |
| authorships[17].is_corresponding | False |
| authorships[17].raw_affiliation_strings | ESPCI Paris, PSL University, Spectrométrie de Masse Biologique et Protéomique, CNRS UMR8249, Paris, France. |
| authorships[18].author.id | https://openalex.org/A5007136885 |
| authorships[18].author.orcid | https://orcid.org/0000-0002-5443-4651 |
| authorships[18].author.display_name | Jutta E. Laiho |
| authorships[18].affiliations[0].raw_affiliation_string | Faculty of Medicine and health technology, tampere University, tampere, Finland. |
| authorships[18].author_position | middle |
| authorships[18].raw_author_name | Jutta Laiho |
| authorships[18].is_corresponding | False |
| authorships[18].raw_affiliation_strings | Faculty of Medicine and health technology, tampere University, tampere, Finland. |
| authorships[19].author.id | https://openalex.org/A5007387317 |
| authorships[19].author.orcid | https://orcid.org/0000-0001-7619-337X |
| authorships[19].author.display_name | Raphaël Scharfmann |
| authorships[19].countries | FR |
| authorships[19].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[19].affiliations[0].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[19].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[19].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[19].institutions[0].type | government |
| authorships[19].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[19].institutions[0].country_code | FR |
| authorships[19].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[19].institutions[1].id | https://openalex.org/I154526488 |
| authorships[19].institutions[1].ror | https://ror.org/02vjkv261 |
| authorships[19].institutions[1].type | government |
| authorships[19].institutions[1].lineage | https://openalex.org/I154526488 |
| authorships[19].institutions[1].country_code | FR |
| authorships[19].institutions[1].display_name | Inserm |
| authorships[19].institutions[2].id | https://openalex.org/I4210141964 |
| authorships[19].institutions[2].ror | https://ror.org/051sk4035 |
| authorships[19].institutions[2].type | facility |
| authorships[19].institutions[2].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[19].institutions[2].country_code | FR |
| authorships[19].institutions[2].display_name | Institut Cochin |
| authorships[19].institutions[3].id | https://openalex.org/I204730241 |
| authorships[19].institutions[3].ror | https://ror.org/05f82e368 |
| authorships[19].institutions[3].type | education |
| authorships[19].institutions[3].lineage | https://openalex.org/I204730241 |
| authorships[19].institutions[3].country_code | FR |
| authorships[19].institutions[3].display_name | Université Paris Cité |
| authorships[19].author_position | middle |
| authorships[19].raw_author_name | Raphael Scharfmann |
| authorships[19].is_corresponding | False |
| authorships[19].raw_affiliation_strings | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[20].author.id | https://openalex.org/A5039754910 |
| authorships[20].author.orcid | https://orcid.org/0000-0002-3653-8107 |
| authorships[20].author.display_name | Michele Solimena |
| authorships[20].countries | DE |
| authorships[20].affiliations[0].institution_ids | https://openalex.org/I4210164390 |
| authorships[20].affiliations[0].raw_affiliation_string | Paul langerhans institute dresden (Plid), helmholtz Munich, University hospital and Faculty of Medicine, tU dresden, dresden, Germany. |
| authorships[20].affiliations[1].institution_ids | https://openalex.org/I4210160326 |
| authorships[20].affiliations[1].raw_affiliation_string | German center for diabetes Research (dZd e.V.), neuherberg, Germany. |
| authorships[20].institutions[0].id | https://openalex.org/I4210160326 |
| authorships[20].institutions[0].ror | https://ror.org/04qq88z54 |
| authorships[20].institutions[0].type | facility |
| authorships[20].institutions[0].lineage | https://openalex.org/I4210160326, https://openalex.org/I4411590659 |
| authorships[20].institutions[0].country_code | DE |
| authorships[20].institutions[0].display_name | German Center for Diabetes Research |
| authorships[20].institutions[1].id | https://openalex.org/I4210164390 |
| authorships[20].institutions[1].ror | https://ror.org/05ke5hb07 |
| authorships[20].institutions[1].type | facility |
| authorships[20].institutions[1].lineage | https://openalex.org/I1305996414, https://openalex.org/I3018134672, https://openalex.org/I4210162051, https://openalex.org/I4210164390, https://openalex.org/I78650965 |
| authorships[20].institutions[1].country_code | DE |
| authorships[20].institutions[1].display_name | Paul Langerhans Institute Dresden |
| authorships[20].author_position | middle |
| authorships[20].raw_author_name | Michele Solimena |
| authorships[20].is_corresponding | False |
| authorships[20].raw_affiliation_strings | German center for diabetes Research (dZd e.V.), neuherberg, Germany., Paul langerhans institute dresden (Plid), helmholtz Munich, University hospital and Faculty of Medicine, tU dresden, dresden, Germany. |
| authorships[21].author.id | https://openalex.org/A5049009904 |
| authorships[21].author.orcid | https://orcid.org/0009-0008-6416-8247 |
| authorships[21].author.display_name | Zuzana Mariničová |
| authorships[21].countries | DE |
| authorships[21].affiliations[0].institution_ids | https://openalex.org/I4210164390 |
| authorships[21].affiliations[0].raw_affiliation_string | Paul langerhans institute dresden (Plid), helmholtz Munich, University hospital and Faculty of Medicine, tU dresden, dresden, Germany. |
| authorships[21].affiliations[1].institution_ids | https://openalex.org/I4210160326 |
| authorships[21].affiliations[1].raw_affiliation_string | German center for diabetes Research (dZd e.V.), neuherberg, Germany. |
| authorships[21].institutions[0].id | https://openalex.org/I4210160326 |
| authorships[21].institutions[0].ror | https://ror.org/04qq88z54 |
| authorships[21].institutions[0].type | facility |
| authorships[21].institutions[0].lineage | https://openalex.org/I4210160326, https://openalex.org/I4411590659 |
| authorships[21].institutions[0].country_code | DE |
| authorships[21].institutions[0].display_name | German Center for Diabetes Research |
| authorships[21].institutions[1].id | https://openalex.org/I4210164390 |
| authorships[21].institutions[1].ror | https://ror.org/05ke5hb07 |
| authorships[21].institutions[1].type | facility |
| authorships[21].institutions[1].lineage | https://openalex.org/I1305996414, https://openalex.org/I3018134672, https://openalex.org/I4210162051, https://openalex.org/I4210164390, https://openalex.org/I78650965 |
| authorships[21].institutions[1].country_code | DE |
| authorships[21].institutions[1].display_name | Paul Langerhans Institute Dresden |
| authorships[21].author_position | middle |
| authorships[21].raw_author_name | Zuzana Marinicova |
| authorships[21].is_corresponding | False |
| authorships[21].raw_affiliation_strings | German center for diabetes Research (dZd e.V.), neuherberg, Germany., Paul langerhans institute dresden (Plid), helmholtz Munich, University hospital and Faculty of Medicine, tU dresden, dresden, Germany. |
| authorships[22].author.id | https://openalex.org/A5083886733 |
| authorships[22].author.orcid | https://orcid.org/0000-0002-9503-9279 |
| authorships[22].author.display_name | Élise Bismuth |
| authorships[22].countries | FR |
| authorships[22].affiliations[0].institution_ids | https://openalex.org/I4210097159, https://openalex.org/I4210126712 |
| authorships[22].affiliations[0].raw_affiliation_string | Assistance Publique Hôpitaux de Paris, Service d’Endocrinologie Pédiatrique, Robert Debré Hospital, Paris, France. |
| authorships[22].institutions[0].id | https://openalex.org/I4210097159 |
| authorships[22].institutions[0].ror | https://ror.org/00pg5jh14 |
| authorships[22].institutions[0].type | healthcare |
| authorships[22].institutions[0].lineage | https://openalex.org/I4210097159 |
| authorships[22].institutions[0].country_code | FR |
| authorships[22].institutions[0].display_name | Assistance Publique – Hôpitaux de Paris |
| authorships[22].institutions[1].id | https://openalex.org/I4210126712 |
| authorships[22].institutions[1].ror | https://ror.org/02dcqy320 |
| authorships[22].institutions[1].type | healthcare |
| authorships[22].institutions[1].lineage | https://openalex.org/I4210097159, https://openalex.org/I4210126712 |
| authorships[22].institutions[1].country_code | FR |
| authorships[22].institutions[1].display_name | Hôpital Robert-Debré |
| authorships[22].author_position | middle |
| authorships[22].raw_author_name | Elise Bismuth |
| authorships[22].is_corresponding | False |
| authorships[22].raw_affiliation_strings | Assistance Publique Hôpitaux de Paris, Service d’Endocrinologie Pédiatrique, Robert Debré Hospital, Paris, France. |
| authorships[23].author.id | https://openalex.org/A5062517567 |
| authorships[23].author.orcid | |
| authorships[23].author.display_name | Nadine Lucidarme |
| authorships[23].countries | FR |
| authorships[23].affiliations[0].institution_ids | https://openalex.org/I4210097159, https://openalex.org/I4210149664 |
| authorships[23].affiliations[0].raw_affiliation_string | Assistance Publique Hôpitaux de Paris, Service de Pédiatrie, Jean Verdier Hospital, Bondy, France. |
| authorships[23].institutions[0].id | https://openalex.org/I4210097159 |
| authorships[23].institutions[0].ror | https://ror.org/00pg5jh14 |
| authorships[23].institutions[0].type | healthcare |
| authorships[23].institutions[0].lineage | https://openalex.org/I4210097159 |
| authorships[23].institutions[0].country_code | FR |
| authorships[23].institutions[0].display_name | Assistance Publique – Hôpitaux de Paris |
| authorships[23].institutions[1].id | https://openalex.org/I4210149664 |
| authorships[23].institutions[1].ror | https://ror.org/04pag4b70 |
| authorships[23].institutions[1].type | healthcare |
| authorships[23].institutions[1].lineage | https://openalex.org/I4210097159, https://openalex.org/I4210149664 |
| authorships[23].institutions[1].country_code | FR |
| authorships[23].institutions[1].display_name | Hôpital Jean-Verdier |
| authorships[23].author_position | middle |
| authorships[23].raw_author_name | Nadine Lucidarme |
| authorships[23].is_corresponding | False |
| authorships[23].raw_affiliation_strings | Assistance Publique Hôpitaux de Paris, Service de Pédiatrie, Jean Verdier Hospital, Bondy, France. |
| authorships[24].author.id | https://openalex.org/A5076976892 |
| authorships[24].author.orcid | https://orcid.org/0000-0003-3790-6140 |
| authorships[24].author.display_name | Janine Sanchez |
| authorships[24].countries | US |
| authorships[24].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[24].affiliations[0].raw_affiliation_string | Department of Pediatrics, Division of Pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA. |
| authorships[24].affiliations[1].institution_ids | https://openalex.org/I4210147155 |
| authorships[24].affiliations[1].raw_affiliation_string | department of Pediatrics, division of Pediatric endocrinology, |
| authorships[24].institutions[0].id | https://openalex.org/I4210147155 |
| authorships[24].institutions[0].ror | https://ror.org/03t432d20 |
| authorships[24].institutions[0].type | healthcare |
| authorships[24].institutions[0].lineage | https://openalex.org/I4210147155 |
| authorships[24].institutions[0].country_code | US |
| authorships[24].institutions[0].display_name | Pediatrics and Genetics |
| authorships[24].institutions[1].id | https://openalex.org/I145608581 |
| authorships[24].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[24].institutions[1].type | education |
| authorships[24].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[24].institutions[1].country_code | US |
| authorships[24].institutions[1].display_name | University of Miami |
| authorships[24].author_position | middle |
| authorships[24].raw_author_name | Janine Sanchez |
| authorships[24].is_corresponding | False |
| authorships[24].raw_affiliation_strings | Department of Pediatrics, Division of Pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA., department of Pediatrics, division of Pediatric endocrinology, |
| authorships[25].author.id | https://openalex.org/A5109632032 |
| authorships[25].author.orcid | |
| authorships[25].author.display_name | Carmen Bustamante |
| authorships[25].countries | US |
| authorships[25].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[25].affiliations[0].raw_affiliation_string | Department of Pediatrics, Division of Pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA. |
| authorships[25].affiliations[1].institution_ids | https://openalex.org/I4210147155 |
| authorships[25].affiliations[1].raw_affiliation_string | department of Pediatrics, division of Pediatric endocrinology, |
| authorships[25].institutions[0].id | https://openalex.org/I4210147155 |
| authorships[25].institutions[0].ror | https://ror.org/03t432d20 |
| authorships[25].institutions[0].type | healthcare |
| authorships[25].institutions[0].lineage | https://openalex.org/I4210147155 |
| authorships[25].institutions[0].country_code | US |
| authorships[25].institutions[0].display_name | Pediatrics and Genetics |
| authorships[25].institutions[1].id | https://openalex.org/I145608581 |
| authorships[25].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[25].institutions[1].type | education |
| authorships[25].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[25].institutions[1].country_code | US |
| authorships[25].institutions[1].display_name | University of Miami |
| authorships[25].author_position | middle |
| authorships[25].raw_author_name | Carmen Bustamante |
| authorships[25].is_corresponding | False |
| authorships[25].raw_affiliation_strings | Department of Pediatrics, Division of Pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA., department of Pediatrics, division of Pediatric endocrinology, |
| authorships[26].author.id | https://openalex.org/A5059180946 |
| authorships[26].author.orcid | https://orcid.org/0000-0002-3211-7647 |
| authorships[26].author.display_name | L. Gómez |
| authorships[26].countries | US |
| authorships[26].affiliations[0].institution_ids | https://openalex.org/I4210147155 |
| authorships[26].affiliations[0].raw_affiliation_string | department of Pediatrics, division of Pediatric endocrinology, |
| authorships[26].affiliations[1].institution_ids | https://openalex.org/I145608581 |
| authorships[26].affiliations[1].raw_affiliation_string | Department of Pediatrics, Division of Pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA. |
| authorships[26].institutions[0].id | https://openalex.org/I4210147155 |
| authorships[26].institutions[0].ror | https://ror.org/03t432d20 |
| authorships[26].institutions[0].type | healthcare |
| authorships[26].institutions[0].lineage | https://openalex.org/I4210147155 |
| authorships[26].institutions[0].country_code | US |
| authorships[26].institutions[0].display_name | Pediatrics and Genetics |
| authorships[26].institutions[1].id | https://openalex.org/I145608581 |
| authorships[26].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[26].institutions[1].type | education |
| authorships[26].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[26].institutions[1].country_code | US |
| authorships[26].institutions[1].display_name | University of Miami |
| authorships[26].author_position | middle |
| authorships[26].raw_author_name | Patricia Gomez |
| authorships[26].is_corresponding | False |
| authorships[26].raw_affiliation_strings | Department of Pediatrics, Division of Pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA., department of Pediatrics, division of Pediatric endocrinology, |
| authorships[27].author.id | https://openalex.org/A5004800654 |
| authorships[27].author.orcid | https://orcid.org/0000-0001-8363-1999 |
| authorships[27].author.display_name | Søren Buus |
| authorships[27].countries | DK |
| authorships[27].affiliations[0].institution_ids | https://openalex.org/I124055696 |
| authorships[27].affiliations[0].raw_affiliation_string | depart-ment of immunology and Microbiology, Faculty of health Sciences, University of copenhagen, copenhagen, denmark. |
| authorships[27].institutions[0].id | https://openalex.org/I124055696 |
| authorships[27].institutions[0].ror | https://ror.org/035b05819 |
| authorships[27].institutions[0].type | education |
| authorships[27].institutions[0].lineage | https://openalex.org/I124055696 |
| authorships[27].institutions[0].country_code | DK |
| authorships[27].institutions[0].display_name | University of Copenhagen |
| authorships[27].author_position | middle |
| authorships[27].raw_author_name | Soren Buus |
| authorships[27].is_corresponding | False |
| authorships[27].raw_affiliation_strings | depart-ment of immunology and Microbiology, Faculty of health Sciences, University of copenhagen, copenhagen, denmark. |
| authorships[28].author.id | https://openalex.org/A5049356241 |
| authorships[28].author.orcid | https://orcid.org/0000-0002-1578-5205 |
| authorships[28].author.display_name | Sylvaine You |
| authorships[28].countries | FR, US |
| authorships[28].affiliations[0].institution_ids | https://openalex.org/I2802732410 |
| authorships[28].affiliations[0].raw_affiliation_string | Indiana Biosciences Research Institute, Indianapolis, IN, USA. |
| authorships[28].affiliations[1].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[28].affiliations[1].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[28].institutions[0].id | https://openalex.org/I1294671590 |
| authorships[28].institutions[0].ror | https://ror.org/02feahw73 |
| authorships[28].institutions[0].type | government |
| authorships[28].institutions[0].lineage | https://openalex.org/I1294671590 |
| authorships[28].institutions[0].country_code | FR |
| authorships[28].institutions[0].display_name | Centre National de la Recherche Scientifique |
| authorships[28].institutions[1].id | https://openalex.org/I154526488 |
| authorships[28].institutions[1].ror | https://ror.org/02vjkv261 |
| authorships[28].institutions[1].type | government |
| authorships[28].institutions[1].lineage | https://openalex.org/I154526488 |
| authorships[28].institutions[1].country_code | FR |
| authorships[28].institutions[1].display_name | Inserm |
| authorships[28].institutions[2].id | https://openalex.org/I4210141964 |
| authorships[28].institutions[2].ror | https://ror.org/051sk4035 |
| authorships[28].institutions[2].type | facility |
| authorships[28].institutions[2].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[28].institutions[2].country_code | FR |
| authorships[28].institutions[2].display_name | Institut Cochin |
| authorships[28].institutions[3].id | https://openalex.org/I204730241 |
| authorships[28].institutions[3].ror | https://ror.org/05f82e368 |
| authorships[28].institutions[3].type | education |
| authorships[28].institutions[3].lineage | https://openalex.org/I204730241 |
| authorships[28].institutions[3].country_code | FR |
| authorships[28].institutions[3].display_name | Université Paris Cité |
| authorships[28].institutions[4].id | https://openalex.org/I2802732410 |
| authorships[28].institutions[4].ror | https://ror.org/04d52p729 |
| authorships[28].institutions[4].type | nonprofit |
| authorships[28].institutions[4].lineage | https://openalex.org/I2802732410 |
| authorships[28].institutions[4].country_code | US |
| authorships[28].institutions[4].display_name | Indiana Biosciences Research Institute |
| authorships[28].author_position | middle |
| authorships[28].raw_author_name | Sylvaine You |
| authorships[28].is_corresponding | False |
| authorships[28].raw_affiliation_strings | Indiana Biosciences Research Institute, Indianapolis, IN, USA., Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[29].author.id | https://openalex.org/A5033971468 |
| authorships[29].author.orcid | https://orcid.org/0000-0002-7211-0319 |
| authorships[29].author.display_name | Alberto Pugliese |
| authorships[29].countries | US |
| authorships[29].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[29].affiliations[0].raw_affiliation_string | diabetes Research institute, leonard Miller School of Medicine, University of Miami, Miami, Fl, USA. |
| authorships[29].affiliations[1].institution_ids | https://openalex.org/I4210110459, https://openalex.org/I4387156432 |
| authorships[29].affiliations[1].raw_affiliation_string | department of diabetes immunology, Arthur Riggs diabetes and Metabolism Research institute, Beckman Research institute, city of hope, duarte, cA, USA. |
| authorships[29].institutions[0].id | https://openalex.org/I4387156432 |
| authorships[29].institutions[0].ror | https://ror.org/05fazth07 |
| authorships[29].institutions[0].type | facility |
| authorships[29].institutions[0].lineage | https://openalex.org/I1301076528, https://openalex.org/I4387156432 |
| authorships[29].institutions[0].country_code | |
| authorships[29].institutions[0].display_name | Beckman Research Institute |
| authorships[29].institutions[1].id | https://openalex.org/I4210110459 |
| authorships[29].institutions[1].ror | https://ror.org/01z1vct10 |
| authorships[29].institutions[1].type | healthcare |
| authorships[29].institutions[1].lineage | https://openalex.org/I1301076528, https://openalex.org/I4210110459 |
| authorships[29].institutions[1].country_code | US |
| authorships[29].institutions[1].display_name | City of Hope |
| authorships[29].institutions[2].id | https://openalex.org/I145608581 |
| authorships[29].institutions[2].ror | https://ror.org/02dgjyy92 |
| authorships[29].institutions[2].type | education |
| authorships[29].institutions[2].lineage | https://openalex.org/I145608581 |
| authorships[29].institutions[2].country_code | US |
| authorships[29].institutions[2].display_name | University of Miami |
| authorships[29].author_position | middle |
| authorships[29].raw_author_name | Alberto Pugliese |
| authorships[29].is_corresponding | False |
| authorships[29].raw_affiliation_strings | department of diabetes immunology, Arthur Riggs diabetes and Metabolism Research institute, Beckman Research institute, city of hope, duarte, cA, USA., diabetes Research institute, leonard Miller School of Medicine, University of Miami, Miami, Fl, USA. |
| authorships[30].author.id | https://openalex.org/A5011722240 |
| authorships[30].author.orcid | https://orcid.org/0000-0003-0370-4145 |
| authorships[30].author.display_name | Heikki Hyöty |
| authorships[30].countries | FI |
| authorships[30].affiliations[0].institution_ids | https://openalex.org/I4210126318 |
| authorships[30].affiliations[0].raw_affiliation_string | department of Pediatrics, tampere University hospital, tampere, Finland. |
| authorships[30].affiliations[1].institution_ids | https://openalex.org/I4210133601 |
| authorships[30].affiliations[1].raw_affiliation_string | Fimlab laboratories, tampere, Finland. |
| authorships[30].affiliations[2].raw_affiliation_string | Faculty of Medicine and health technology, tampere University, tampere, Finland. |
| authorships[30].institutions[0].id | https://openalex.org/I4210133601 |
| authorships[30].institutions[0].ror | https://ror.org/031y6w871 |
| authorships[30].institutions[0].type | company |
| authorships[30].institutions[0].lineage | https://openalex.org/I4210133601 |
| authorships[30].institutions[0].country_code | FI |
| authorships[30].institutions[0].display_name | Fimlab (Finland) |
| authorships[30].institutions[1].id | https://openalex.org/I4210126318 |
| authorships[30].institutions[1].ror | https://ror.org/02hvt5f17 |
| authorships[30].institutions[1].type | healthcare |
| authorships[30].institutions[1].lineage | https://openalex.org/I4210126318 |
| authorships[30].institutions[1].country_code | FI |
| authorships[30].institutions[1].display_name | Tampere University Hospital |
| authorships[30].author_position | middle |
| authorships[30].raw_author_name | Heikki Hyoty |
| authorships[30].is_corresponding | False |
| authorships[30].raw_affiliation_strings | Faculty of Medicine and health technology, tampere University, tampere, Finland., Fimlab laboratories, tampere, Finland., department of Pediatrics, tampere University hospital, tampere, Finland. |
| authorships[31].author.id | https://openalex.org/A5061334836 |
| authorships[31].author.orcid | https://orcid.org/0000-0003-1531-8583 |
| authorships[31].author.display_name | Teresa Rodríguez-Calvo |
| authorships[31].countries | DE |
| authorships[31].affiliations[0].institution_ids | https://openalex.org/I4210152419, https://openalex.org/I4210160326, https://openalex.org/I44260953 |
| authorships[31].affiliations[0].raw_affiliation_string | German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany. |
| authorships[31].affiliations[1].institution_ids | https://openalex.org/I3018134672 |
| authorships[31].affiliations[1].raw_affiliation_string | Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany. |
| authorships[31].institutions[0].id | https://openalex.org/I4210152419 |
| authorships[31].institutions[0].ror | https://ror.org/04ews3245 |
| authorships[31].institutions[0].type | facility |
| authorships[31].institutions[0].lineage | https://openalex.org/I315704651, https://openalex.org/I4210152419, https://openalex.org/I44260953 |
| authorships[31].institutions[0].country_code | DE |
| authorships[31].institutions[0].display_name | Deutsches Diabetes-Zentrum e.V. |
| authorships[31].institutions[1].id | https://openalex.org/I4210160326 |
| authorships[31].institutions[1].ror | https://ror.org/04qq88z54 |
| authorships[31].institutions[1].type | facility |
| authorships[31].institutions[1].lineage | https://openalex.org/I4210160326, https://openalex.org/I4411590659 |
| authorships[31].institutions[1].country_code | DE |
| authorships[31].institutions[1].display_name | German Center for Diabetes Research |
| authorships[31].institutions[2].id | https://openalex.org/I44260953 |
| authorships[31].institutions[2].ror | https://ror.org/024z2rq82 |
| authorships[31].institutions[2].type | education |
| authorships[31].institutions[2].lineage | https://openalex.org/I44260953 |
| authorships[31].institutions[2].country_code | DE |
| authorships[31].institutions[2].display_name | Heinrich Heine University Düsseldorf |
| authorships[31].institutions[3].id | https://openalex.org/I3018134672 |
| authorships[31].institutions[3].ror | https://ror.org/00cfam450 |
| authorships[31].institutions[3].type | facility |
| authorships[31].institutions[3].lineage | https://openalex.org/I1305996414, https://openalex.org/I3018134672 |
| authorships[31].institutions[3].country_code | DE |
| authorships[31].institutions[3].display_name | Helmholtz Zentrum München |
| authorships[31].author_position | middle |
| authorships[31].raw_author_name | Teresa Rodriguez-Calvo |
| authorships[31].is_corresponding | False |
| authorships[31].raw_affiliation_strings | German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany. |
| authorships[32].author.id | https://openalex.org/A5063133241 |
| authorships[32].author.orcid | https://orcid.org/0000-0003-2685-2052 |
| authorships[32].author.display_name | Malin Flodström‐Tullberg |
| authorships[32].affiliations[0].raw_affiliation_string | center for infectious Medicine, de-partment of Medicine huddinge, Karolinska institutet, Karolinska University hospi-tal huddinge, Stockholm, Sweden. |
| authorships[32].author_position | middle |
| authorships[32].raw_author_name | Malin Flodstrom-Tullberg |
| authorships[32].is_corresponding | False |
| authorships[32].raw_affiliation_strings | center for infectious Medicine, de-partment of Medicine huddinge, Karolinska institutet, Karolinska University hospi-tal huddinge, Stockholm, Sweden. |
| authorships[33].author.id | https://openalex.org/A5051848877 |
| authorships[33].author.orcid | https://orcid.org/0000-0002-9846-8861 |
| authorships[33].author.display_name | Roberto Mallone |
| authorships[33].countries | FR, US |
| authorships[33].affiliations[0].institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210141964 |
| authorships[33].affiliations[0].raw_affiliation_string | Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France. |
| authorships[33].affiliations[1].institution_ids | https://openalex.org/I4210092774, https://openalex.org/I4210097159 |
| authorships[33].affiliations[1].raw_affiliation_string | Assistance Publique Hôpitaux de Paris, Service de Diabétologie et Immunologie Clinique, Cochin Hospital, Paris, France. |
| authorships[33].affiliations[2].institution_ids | https://openalex.org/I2802732410 |
| authorships[33].affiliations[2].raw_affiliation_string | indiana Biosciences Research institute, indianapolis, in, USA. |
| authorships[33].institutions[0].id | https://openalex.org/I4210097159 |
| authorships[33].institutions[0].ror | https://ror.org/00pg5jh14 |
| authorships[33].institutions[0].type | healthcare |
| authorships[33].institutions[0].lineage | https://openalex.org/I4210097159 |
| authorships[33].institutions[0].country_code | FR |
| authorships[33].institutions[0].display_name | Assistance Publique – Hôpitaux de Paris |
| authorships[33].institutions[1].id | https://openalex.org/I1294671590 |
| authorships[33].institutions[1].ror | https://ror.org/02feahw73 |
| authorships[33].institutions[1].type | government |
| authorships[33].institutions[1].lineage | https://openalex.org/I1294671590 |
| authorships[33].institutions[1].country_code | FR |
| authorships[33].institutions[1].display_name | Centre National de la Recherche Scientifique |
| authorships[33].institutions[2].id | https://openalex.org/I4210092774 |
| authorships[33].institutions[2].ror | https://ror.org/00ph8tk69 |
| authorships[33].institutions[2].type | healthcare |
| authorships[33].institutions[2].lineage | https://openalex.org/I4210092774, https://openalex.org/I4210097159, https://openalex.org/I4210124464 |
| authorships[33].institutions[2].country_code | FR |
| authorships[33].institutions[2].display_name | Hôpital Cochin |
| authorships[33].institutions[3].id | https://openalex.org/I154526488 |
| authorships[33].institutions[3].ror | https://ror.org/02vjkv261 |
| authorships[33].institutions[3].type | government |
| authorships[33].institutions[3].lineage | https://openalex.org/I154526488 |
| authorships[33].institutions[3].country_code | FR |
| authorships[33].institutions[3].display_name | Inserm |
| authorships[33].institutions[4].id | https://openalex.org/I4210141964 |
| authorships[33].institutions[4].ror | https://ror.org/051sk4035 |
| authorships[33].institutions[4].type | facility |
| authorships[33].institutions[4].lineage | https://openalex.org/I1294671590, https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210096427, https://openalex.org/I4210141964 |
| authorships[33].institutions[4].country_code | FR |
| authorships[33].institutions[4].display_name | Institut Cochin |
| authorships[33].institutions[5].id | https://openalex.org/I204730241 |
| authorships[33].institutions[5].ror | https://ror.org/05f82e368 |
| authorships[33].institutions[5].type | education |
| authorships[33].institutions[5].lineage | https://openalex.org/I204730241 |
| authorships[33].institutions[5].country_code | FR |
| authorships[33].institutions[5].display_name | Université Paris Cité |
| authorships[33].institutions[6].id | https://openalex.org/I2802732410 |
| authorships[33].institutions[6].ror | https://ror.org/04d52p729 |
| authorships[33].institutions[6].type | nonprofit |
| authorships[33].institutions[6].lineage | https://openalex.org/I2802732410 |
| authorships[33].institutions[6].country_code | US |
| authorships[33].institutions[6].display_name | Indiana Biosciences Research Institute |
| authorships[33].author_position | last |
| authorships[33].raw_author_name | Roberto Mallone |
| authorships[33].is_corresponding | True |
| authorships[33].raw_affiliation_strings | Assistance Publique Hôpitaux de Paris, Service de Diabétologie et Immunologie Clinique, Cochin Hospital, Paris, France., Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., indiana Biosciences Research institute, indianapolis, in, USA. |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.science.org/doi/pdf/10.1126/sciadv.adl1122?download=true |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2024-03-07T00:00:00 |
| display_name | Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T11171 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9998999834060669 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1311 |
| primary_topic.subfield.display_name | Genetics |
| primary_topic.display_name | Diabetes and associated disorders |
| related_works | https://openalex.org/W2560506355, https://openalex.org/W2048339817, https://openalex.org/W2069225789, https://openalex.org/W1504084256, https://openalex.org/W2463432521, https://openalex.org/W1902890366, https://openalex.org/W2160129988, https://openalex.org/W2136791659, https://openalex.org/W262675909, https://openalex.org/W1565280315 |
| cited_by_count | 14 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 6 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 8 |
| locations_count | 5 |
| best_oa_location.id | doi:10.1126/sciadv.adl1122 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2737427234 |
| best_oa_location.source.issn | 2375-2548 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2375-2548 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Science Advances |
| best_oa_location.source.host_organization | https://openalex.org/P4310315823 |
| best_oa_location.source.host_organization_name | American Association for the Advancement of Science |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310315823 |
| best_oa_location.license | |
| best_oa_location.pdf_url | https://www.science.org/doi/pdf/10.1126/sciadv.adl1122?download=true |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Science Advances |
| best_oa_location.landing_page_url | https://doi.org/10.1126/sciadv.adl1122 |
| primary_location.id | doi:10.1126/sciadv.adl1122 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2737427234 |
| primary_location.source.issn | 2375-2548 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2375-2548 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Science Advances |
| primary_location.source.host_organization | https://openalex.org/P4310315823 |
| primary_location.source.host_organization_name | American Association for the Advancement of Science |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310315823 |
| primary_location.license | |
| primary_location.pdf_url | https://www.science.org/doi/pdf/10.1126/sciadv.adl1122?download=true |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Science Advances |
| primary_location.landing_page_url | https://doi.org/10.1126/sciadv.adl1122 |
| publication_date | 2024-03-06 |
| publication_year | 2024 |
| referenced_works | https://openalex.org/W4323531859, https://openalex.org/W2097150236, https://openalex.org/W2900756670, https://openalex.org/W2030685032, https://openalex.org/W2049204060, https://openalex.org/W4382200058, https://openalex.org/W2990466613, https://openalex.org/W4281761207, https://openalex.org/W2043204562, https://openalex.org/W2126981851, https://openalex.org/W2914264295, https://openalex.org/W3021971030, https://openalex.org/W2514506174, https://openalex.org/W1977492930, https://openalex.org/W3048364861, https://openalex.org/W2885248212, https://openalex.org/W2883165621, https://openalex.org/W2785684315, https://openalex.org/W3086848320, https://openalex.org/W3201345788, https://openalex.org/W3204623738, https://openalex.org/W3015687710, https://openalex.org/W4387301346, https://openalex.org/W3197297000, https://openalex.org/W2147692295, https://openalex.org/W2950437009, https://openalex.org/W2016305769, https://openalex.org/W2030955189, https://openalex.org/W4324129564, https://openalex.org/W2019446509, https://openalex.org/W2912648593, https://openalex.org/W2126648894, https://openalex.org/W2138937703, https://openalex.org/W2021359578, https://openalex.org/W1970100177, https://openalex.org/W3029950012, https://openalex.org/W3094217856, https://openalex.org/W2164707000, https://openalex.org/W1984959662, https://openalex.org/W2016578964, https://openalex.org/W4386453584, https://openalex.org/W4366277387, https://openalex.org/W2148270513, https://openalex.org/W2099685714, https://openalex.org/W2782324869, https://openalex.org/W2274583647, https://openalex.org/W1984454731, https://openalex.org/W2106247702, https://openalex.org/W2130225335, https://openalex.org/W2952481429, https://openalex.org/W3021714323, https://openalex.org/W2053001784, https://openalex.org/W2162789526, https://openalex.org/W3099064910 |
| referenced_works_count | 54 |
| abstract_inverted_index.+ | 56, 124, 143 |
| abstract_inverted_index.1 | 16, 139 |
| abstract_inverted_index.B | 1 |
| abstract_inverted_index.T | 28, 57, 75, 82, 112, 125, 144 |
| abstract_inverted_index.a | 63, 85 |
| abstract_inverted_index.I, | 46 |
| abstract_inverted_index.We | 18 |
| abstract_inverted_index.by | 36, 73, 107, 110 |
| abstract_inverted_index.ex | 118 |
| abstract_inverted_index.in | 38, 115 |
| abstract_inverted_index.is | 8 |
| abstract_inverted_index.of | 4, 65 |
| abstract_inverted_index.to | 100, 128, 154, 158 |
| abstract_inverted_index.β | 6, 11, 24, 31, 90, 95 |
| abstract_inverted_index.CD8 | 55, 123, 142 |
| abstract_inverted_index.CVB | 21, 37, 86, 108, 134, 150 |
| abstract_inverted_index.Our | 114 |
| abstract_inverted_index.and | 14, 26, 47, 117, 148, 160 |
| abstract_inverted_index.for | 133, 137 |
| abstract_inverted_index.how | 20 |
| abstract_inverted_index.the | 131 |
| abstract_inverted_index.was | 71 |
| abstract_inverted_index.CVB, | 129 |
| abstract_inverted_index.GAD. | 93 |
| abstract_inverted_index.cell | 12, 29, 91, 126 |
| abstract_inverted_index.data | 120 |
| abstract_inverted_index.few, | 49 |
| abstract_inverted_index.from | 59 |
| abstract_inverted_index.more | 104 |
| abstract_inverted_index.only | 68 |
| abstract_inverted_index.than | 109 |
| abstract_inverted_index.that | 77 |
| abstract_inverted_index.type | 15, 138 |
| abstract_inverted_index.vivo | 119 |
| abstract_inverted_index.were | 33, 103 |
| abstract_inverted_index.with | 10, 89 |
| abstract_inverted_index.(CVB) | 2 |
| abstract_inverted_index.(HLA) | 44 |
| abstract_inverted_index.PD-1. | 81 |
| abstract_inverted_index.cells | 7, 25, 32, 58, 76, 83, 145 |
| abstract_inverted_index.class | 45 |
| abstract_inverted_index.human | 23, 41 |
| abstract_inverted_index.these | 66 |
| abstract_inverted_index.viral | 52 |
| abstract_inverted_index.vitro | 116 |
| abstract_inverted_index.which | 97 |
| abstract_inverted_index.cells, | 96 |
| abstract_inverted_index.cells. | 113 |
| abstract_inverted_index.follow | 156 |
| abstract_inverted_index.formed | 98 |
| abstract_inverted_index.killed | 106 |
| abstract_inverted_index.marker | 80 |
| abstract_inverted_index.trials | 136 |
| abstract_inverted_index.vitro, | 39 |
| abstract_inverted_index.affects | 22 |
| abstract_inverted_index.another | 69 |
| abstract_inverted_index.antigen | 43, 92 |
| abstract_inverted_index.epitope | 87 |
| abstract_inverted_index.limited | 122 |
| abstract_inverted_index.provide | 152 |
| abstract_inverted_index.Infected | 94 |
| abstract_inverted_index.anti-CVB | 27 |
| abstract_inverted_index.diabetes | 140 |
| abstract_inverted_index.epitopes | 151 |
| abstract_inverted_index.fraction | 64 |
| abstract_inverted_index.infected | 35 |
| abstract_inverted_index.response | 157 |
| abstract_inverted_index.selected | 50 |
| abstract_inverted_index.targeted | 72 |
| abstract_inverted_index.HLA-bound | 51 |
| abstract_inverted_index.diabetes. | 17 |
| abstract_inverted_index.expressed | 78 |
| abstract_inverted_index.filopodia | 99 |
| abstract_inverted_index.highlight | 121 |
| abstract_inverted_index.infection | 3, 159 |
| abstract_inverted_index.leukocyte | 42 |
| abstract_inverted_index.peptides. | 53 |
| abstract_inverted_index.peptides; | 67 |
| abstract_inverted_index.presented | 48 |
| abstract_inverted_index.propagate | 101 |
| abstract_inverted_index.rationale | 132 |
| abstract_inverted_index.responses | 127 |
| abstract_inverted_index.associated | 9 |
| abstract_inverted_index.biomarkers | 153 |
| abstract_inverted_index.exhaustion | 79 |
| abstract_inverted_index.infection, | 102 |
| abstract_inverted_index.pancreatic | 5 |
| abstract_inverted_index.recognized | 62 |
| abstract_inverted_index.responses. | 30 |
| abstract_inverted_index.structural | 147 |
| abstract_inverted_index.supporting | 130 |
| abstract_inverted_index.Circulating | 54 |
| abstract_inverted_index.efficiently | 34, 105 |
| abstract_inverted_index.individuals | 61 |
| abstract_inverted_index.prevention. | 141 |
| abstract_inverted_index.recognizing | 84, 146 |
| abstract_inverted_index.subfraction | 70 |
| abstract_inverted_index.vaccination | 135 |
| abstract_inverted_index.CVB-reactive | 111 |
| abstract_inverted_index.autoimmunity | 13 |
| abstract_inverted_index.investigated | 19 |
| abstract_inverted_index.vaccination. | 161 |
| abstract_inverted_index.cross-reacted | 88 |
| abstract_inverted_index.nonstructural | 149 |
| abstract_inverted_index.Coxsackievirus | 0 |
| abstract_inverted_index.differentially | 155 |
| abstract_inverted_index.down-regulated | 40 |
| abstract_inverted_index.effector/memory | 74 |
| abstract_inverted_index.CVB–seropositive | 60 |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 98 |
| corresponding_author_ids | https://openalex.org/A5051848877 |
| countries_distinct_count | 6 |
| institutions_distinct_count | 34 |
| corresponding_institution_ids | https://openalex.org/I1294671590, https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I2802732410, https://openalex.org/I4210092774, https://openalex.org/I4210097159, https://openalex.org/I4210141964 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.75 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.98499225 |
| citation_normalized_percentile.is_in_top_1_percent | True |
| citation_normalized_percentile.is_in_top_10_percent | True |