Creating an RF Pulse Simulation Model for Whole-Brain MRSI at 7T Article Swipe
Diese Diplomarbeit befasst sich damit, wie man Magnetresonanzspektroskopie-Bildgebung (MRSI) durch optimierte Radio-Frequenz-Anregungspulse (RF Pulse) verbessern kann. Im Rahmen der Arbeit wurde ein Simulationsmodell programmiert und verwendet, um verschiedene RF Pulse zu simulieren und zu bewerten. Insbesondere wurden realistische Pulse, welche auf einem sinc-Profil basieren, mit idealen Anregungspulsen mit binären Profilen verglichen. In diesem Modell wurde in einem ersten Schritt ein Puls simuliert und ein numerisches Hirnphantom generiert. Das Phantom bestand aus einer Hirnregion und einer sie umschließenden Lipidregion; seine Form basierte auf Masken aus einer Probandenmessung. In einem zweiten Schritt wurde der simulierte Puls verwendet, um ein Volumen im Phantom anzuregen. Verschiedene Volumenspositionen, -orientierungen und -ausdehnungen wurden simuliert. Eine Messung der angeregten Regionen wurde als Aufnahme eines zentralen Ausschnitts des Ortsfrequenzraums (k-Raum) modelliert, wodurch wie bei einer richtigen MRSI-Messung Artefakte entstanden. Schließlich wurden die simulierten Signale in ausgewählten räumlichen und spektralen Regionen ausgewertet. Verschiedene Pulse wurden im Hinblick auf die Menge an Signal im Hirn, die durch die außerhalb befindlichen Lipide verursacht worden sind, verglichen. Ein Puls, der beispielsweise verhindert, dass Lipide in Lipidregionen im Hirn angeregt werden, sodass ihr Signal ins Hirn einstreut, könnte eine Verbesserung zu derzeit verwendeten Pulsen bedeuten.
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Metadata
- Type
- dissertation
- Language
- de
- Landing Page
- https://doi.org/10.34726/hss.2020.62612
- OA Status
- green
- Related Works
- 20
- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3207773476Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.34726/hss.2020.62612Digital Object Identifier
- Title
-
Creating an RF Pulse Simulation Model for Whole-Brain MRSI at 7TWork title
- Type
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dissertationOpenAlex work type
- Language
-
dePrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-01-01Full publication date if available
- Authors
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Philipp LazenList of authors in order
- Landing page
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https://doi.org/10.34726/hss.2020.62612Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
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https://doi.org/10.34726/hss.2020.62612Direct OA link when available
- Concepts
-
Radio frequency, Magnetic resonance imaging, Nuclear magnetic resonance, Pulse (music), Physics, Functional magnetic resonance imaging, Computer science, Optics, Medicine, Psychology, Neuroscience, Telecommunications, Radiology, DetectorTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- Related works (count)
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20Other works algorithmically related by OpenAlex
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| abstract_inverted_index.Magnetresonanzspektroskopie-Bildgebung | 7 |
| cited_by_percentile_year | |
| corresponding_author_ids | https://openalex.org/A5083940126 |
| countries_distinct_count | 0 |
| institutions_distinct_count | 1 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/7 |
| sustainable_development_goals[0].score | 0.4699999988079071 |
| sustainable_development_goals[0].display_name | Affordable and clean energy |
| citation_normalized_percentile.value | 0.29098511 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |