Curcumin attenuates collagen-induced inflammatory response through the “gut-brain axis” Article Swipe
Related Concepts
Curcumin
Vesicular acetylcholine transporter
Pharmacology
Cholinergic
Vagus nerve
Acetylcholine
Medicine
Choline acetyltransferase
Arthritis
Chemistry
Internal medicine
Stimulation
Yannong Dou
,
Jinque Luo
,
Xin Wu
,
Zhifeng Wei
,
Bei Tong
,
Juntao Yu
,
Ting Wang
,
Xinyu Zhang
,
Yan Yang
,
Xusheng Yuan
,
Peng Zhao
,
Yufeng Xia
,
Huijuan Hu
,
Yue Dai
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1186/s12974-017-1047-7
· OA: W2782411093
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1186/s12974-017-1047-7
· OA: W2782411093
Our results demonstrate that curcumin attenuates CIA through the "gut-brain axis" by modulating the function of the cholinergic system. These findings provide a novel approach for mechanistic studies of anti-arthritic compounds with low oral absorption and bioavailability.
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