Cusp-overlap view versus three cusp coplanar view during transcatheter aortic valve replacement using self-expandable valves: a systematic review, meta-analysis and meta-regression Article Swipe
Basma Badrawy Khalefa
,
Ahmed K. Awad
,
Ahmed R Gonnah
,
Mazen Negmeldin Aly Yassin
,
Nada G. Hamam
,
Hatem Eldeeb
,
Mohamed Ramadan
,
Ali Dway
,
Karim Alsalhi
,
Mazen Osman
,
Basel F. Alqeeq
,
Mohammed Al‐Tawil
,
Serge Sicouri
,
Massimo Baudo
,
Yoshiyuki Yamashita
,
Basel Ramlawi
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1186/s12872-025-05009-8
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1186/s12872-025-05009-8
Transcatheter aortic valve replacement (TAVR) is currently the treatment of choice for most patients with severe aortic stenosis. We conducted this meta-analysis to compare the outcomes of the cusp overlap technique (COT) versus the standard three-cusp technique during self-expandable valves implantation. We systematically searched PubMed, Scopus, Embase, Cochrane, and Web of Science (WOS) from inception to March 5, 2024. To estimate the effect size, dichotomous outcomes were pooled as RR, and continuous outcome was pooled as MD with their respective 95% CI. We included seventeen studies with a total of 3,129 patients in cusp-overlap technique (COT) arm and 2,818 patients in standard technique (ST) arm. The rate of 30-day mortality was borderline reduced in COT compared with ST, however, with no significant difference (RR = 0.61; 95% CI: [0.37-1.00], P = 0.05). Regarding conduction abnormalities, COT was related to lower risk of complete atrioventricular (AV) block (RR = 0.51; 95% CI: [0.37-0.69], P < 0.01), and permanent pacemaker implantation (PPM) (RR = 0.56; 95% CI: [0.46-0.70], P < 0.01). Mild to severe paravalvular leak (PVL) (RR = 1.00; 95% CI: [0.66-1.51], P = 1.00, I2 = 62%; P = 0.02) were comparable between COT and ST. Our study findings suggest that COT offers several advantages over ST, including reduced 30-day mortality, bleeding complications, and shorter procedural duration. The COT most importantly lowers the risk of conduction abnormalities, and hence the incidence PPM.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1186/s12872-025-05009-8
- https://bmccardiovascdisord.biomedcentral.com/counter/pdf/10.1186/s12872-025-05009-8
- OA Status
- gold
- References
- 55
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4413406149
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4413406149Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1186/s12872-025-05009-8Digital Object Identifier
- Title
-
Cusp-overlap view versus three cusp coplanar view during transcatheter aortic valve replacement using self-expandable valves: a systematic review, meta-analysis and meta-regressionWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-08-21Full publication date if available
- Authors
-
Basma Badrawy Khalefa, Ahmed K. Awad, Ahmed R Gonnah, Mazen Negmeldin Aly Yassin, Nada G. Hamam, Hatem Eldeeb, Mohamed Ramadan, Ali Dway, Karim Alsalhi, Mazen Osman, Basel F. Alqeeq, Mohammed Al‐Tawil, Serge Sicouri, Massimo Baudo, Yoshiyuki Yamashita, Basel RamlawiList of authors in order
- Landing page
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https://doi.org/10.1186/s12872-025-05009-8Publisher landing page
- PDF URL
-
https://bmccardiovascdisord.biomedcentral.com/counter/pdf/10.1186/s12872-025-05009-8Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://bmccardiovascdisord.biomedcentral.com/counter/pdf/10.1186/s12872-025-05009-8Direct OA link when available
- Concepts
-
Angiology, Cusp (singularity), Cardiology, Valve replacement, Medicine, Cardiac surgery, Meta-analysis, Internal medicine, Stenosis, Mathematics, GeometryTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- References (count)
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55Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| referenced_works | https://openalex.org/W4390659981, https://openalex.org/W2933135985, https://openalex.org/W2945486426, https://openalex.org/W2751630023, https://openalex.org/W2907713697, https://openalex.org/W3115258265, https://openalex.org/W2831361703, https://openalex.org/W4386034592, https://openalex.org/W4313330287, https://openalex.org/W3197012809, https://openalex.org/W2910298507, https://openalex.org/W3203438471, https://openalex.org/W4389246037, https://openalex.org/W3118615836, https://openalex.org/W3091655327, https://openalex.org/W4367609003, https://openalex.org/W4390755554, https://openalex.org/W4220806496, https://openalex.org/W4310576491, https://openalex.org/W4293740510, https://openalex.org/W4328100101, https://openalex.org/W4385382764, https://openalex.org/W3157571414, https://openalex.org/W4281617717, https://openalex.org/W3197307538, https://openalex.org/W4206768721, https://openalex.org/W4367670126, https://openalex.org/W4410087140, https://openalex.org/W4386046275, https://openalex.org/W4362522008, https://openalex.org/W2121702486, https://openalex.org/W3156434758, https://openalex.org/W2997371548, https://openalex.org/W2551157276, https://openalex.org/W2790332731, https://openalex.org/W3094151152, https://openalex.org/W2021944894, https://openalex.org/W2308734203, https://openalex.org/W2549498313, https://openalex.org/W2970602664, https://openalex.org/W4317399553, https://openalex.org/W4292308703, https://openalex.org/W4317425066, https://openalex.org/W4389037188, https://openalex.org/W4390340971, https://openalex.org/W2151693220, https://openalex.org/W3112785303, https://openalex.org/W4321202037, https://openalex.org/W2995530911, https://openalex.org/W4383868384, https://openalex.org/W2560438049, https://openalex.org/W4205565352, https://openalex.org/W4388831502, https://openalex.org/W3180420739, https://openalex.org/W2888446624 |
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