Data for: Comparison of methods for measuring blood lactate and blood gases Article Swipe
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· 2020
· Open Access
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· DOI: https://doi.org/10.7910/dvn/glhp4d
· OA: W4398651138
<p>This dataset was generated by a sub-study of a prospective observational study of children admitted with falciparum malaria to Kilifi District Hospital as part of a core database to determine prognostic features in African children. In the main study, the prognostic significance of malarial pigment (in red cells, and in white cells), together with other laboratory and clinical parameters are being determined (<a href="https://doi.org/10.1016/j.trstmh.2005.09.021"> doi: 10.1016/j.trstmh.2005.09.021</a>). </p> <p>The purpose of the study was to compare the current SMAC methods for measuring acid/base status (the pHOx machine) and whole blood lactate concentrations (Lactate Pro) with the standard methods previously used in two sites. The data generated was considered in deciding which methods should be recommended for all SMAC sites. The Severe Malaria in African Children (SMAC) network’s site in Kenya was the only site routinely measuring acid/base status prior to the pigment study, and this site had been using the Instrumentation Laboratory 1620 blood gas analyzer to assess acid/base status. The SMAC site in Kenya had been using the Analox GM7 machine (Analox Instruments Ltd., London, UK) for its lactate measurements, and the Ghanaian site had been using the YSI 2300 analyzer (YSI Incorporated/YSI Life Sciences, Hampshire, England) for its lactate measurements. In a pilot study, agreement between the Lactate Pro and the YSI 2300 in Ghana was very good, but agreement between the Lactate Pro and the Analox GM7 in Kenya was poor. To eliminate site-to-site variability, one of the YSI 2300 machines from Ghana has been shipped to Kenya so that a direct comparison between the YSI 2300 and the Analox GM7 can be made in Kenya </p> <p>Comparisons were made between two different Lactate Pro machines, between test strips from two different lots in the two different Lactate Pro machines, between the Lactate Pro analyzers, and between the Lactate Pro analyzers and two reference standards in Kenya. </p>
