Data from The Effect of Patient and Contextual Characteristics on Racial/Ethnic Disparity in Breast Cancer Mortality Article Swipe
YOU?
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· 2023
· Open Access
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· DOI: https://doi.org/10.1158/1055-9965.c.6515452.v1
Background: Racial/ethnic disparity in breast cancer–specific mortality in the United States is well documented. We examined whether accounting for racial/ethnic differences in the prevalence of clinical, patient, and lifestyle and contextual factors that are associated with breast cancer–specific mortality can explain this disparity.Methods: The California Breast Cancer Survivorship Consortium combined interview data from six California-based breast cancer studies with cancer registry data to create a large, racially diverse cohort of women with primary invasive breast cancer. We examined the contribution of variables in a previously reported Cox regression baseline model plus additional contextual, physical activity, body size, and comorbidity variables to the racial/ethnic disparity in breast cancer–specific mortality.Results: The cohort comprised 12,098 women. Fifty-four percent were non-Latina Whites, 17% African Americans, 17% Latinas, and 12% Asian Americans. In a model adjusting only for age and study, breast cancer–specific HRs relative to Whites were 1.69 (95% CI, 1.46–1.96), 1.00 (0.84–1.19), and 0.52 (0.33–0.85) for African Americans, Latinas, and Asian Americans, respectively. Adjusting for baseline-model variables decreased disparity primarily by reducing the HR for African Americans to 1.13 (0.96–1.33). The most influential variables were related to disease characteristics, neighborhood socioeconomic status, and smoking status at diagnosis. Other variables had negligible impact on disparity.Conclusions: Although contextual, physical activity, body size, and comorbidity variables may influence breast cancer–specific mortality, they do not explain racial/ethnic mortality disparity.Impact: Other factors besides those investigated here may explain the existing racial/ethnic disparity in mortality. Cancer Epidemiol Biomarkers Prev; 25(7); 1064–72. ©2016 AACR.
Related Topics
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.1158/1055-9965.c.6515452.v1
- OA Status
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- 10
- OpenAlex ID
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Raw OpenAlex JSON
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https://openalex.org/W4361948707Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1158/1055-9965.c.6515452.v1Digital Object Identifier
- Title
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Data from The Effect of Patient and Contextual Characteristics on Racial/Ethnic Disparity in Breast Cancer MortalityWork title
- Type
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preprintOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-03-31Full publication date if available
- Authors
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Richard Sposto, Theresa H.M. Keegan, Cheryl Vigen, Marilyn L. Kwan, Leslie Bernstein, Esther M. John, Iona Cheng, Juan Yang, Jocelyn Koo, Allison W. Kurian, Bette J. Caan, Yani Lu, Kristine R. Monroe, Salma Shariff‐Marco, Scarlett Lin Gomez, Anna H. WuList of authors in order
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https://doi.org/10.1158/1055-9965.c.6515452.v1Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.1158/1055-9965.c.6515452.v1Direct OA link when available
- Concepts
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Breast cancer, Medicine, Demography, Ethnic group, Cohort, Socioeconomic status, Survivorship curve, Proportional hazards model, Cancer, Cohort study, Gerontology, Internal medicine, Oncology, Population, Environmental health, Sociology, AnthropologyTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.Asian | 125, 157 |
| abstract_inverted_index.Other | 194, 222 |
| abstract_inverted_index.Prev; | 239 |
| abstract_inverted_index.model | 89, 129 |
| abstract_inverted_index.size, | 96, 206 |
| abstract_inverted_index.those | 225 |
| abstract_inverted_index.women | 70 |
| abstract_inverted_index.12,098 | 111 |
| abstract_inverted_index.25(7); | 240 |
| abstract_inverted_index.Breast | 45 |
| abstract_inverted_index.Cancer | 46 |
| abstract_inverted_index.States | 10 |
| abstract_inverted_index.United | 9 |
| abstract_inverted_index.Whites | 141 |
| abstract_inverted_index.breast | 4, 36, 55, 74, 105, 136, 212 |
| abstract_inverted_index.cancer | 56, 59 |
| abstract_inverted_index.cohort | 68, 109 |
| abstract_inverted_index.create | 63 |
| abstract_inverted_index.impact | 198 |
| abstract_inverted_index.large, | 65 |
| abstract_inverted_index.status | 191 |
| abstract_inverted_index.study, | 135 |
| abstract_inverted_index.women. | 112 |
| abstract_inverted_index.©2016 | 242 |
| abstract_inverted_index.African | 119, 153, 172 |
| abstract_inverted_index.Whites, | 117 |
| abstract_inverted_index.besides | 224 |
| abstract_inverted_index.cancer. | 75 |
| abstract_inverted_index.disease | 184 |
| abstract_inverted_index.diverse | 67 |
| abstract_inverted_index.explain | 40, 218, 229 |
| abstract_inverted_index.factors | 31, 223 |
| abstract_inverted_index.percent | 114 |
| abstract_inverted_index.primary | 72 |
| abstract_inverted_index.related | 182 |
| abstract_inverted_index.smoking | 190 |
| abstract_inverted_index.status, | 188 |
| abstract_inverted_index.studies | 57 |
| abstract_inverted_index.whether | 16 |
| abstract_inverted_index.Although | 201 |
| abstract_inverted_index.Latinas, | 122, 155 |
| abstract_inverted_index.baseline | 88 |
| abstract_inverted_index.combined | 49 |
| abstract_inverted_index.examined | 15, 77 |
| abstract_inverted_index.existing | 231 |
| abstract_inverted_index.invasive | 73 |
| abstract_inverted_index.patient, | 26 |
| abstract_inverted_index.physical | 93, 203 |
| abstract_inverted_index.racially | 66 |
| abstract_inverted_index.reducing | 168 |
| abstract_inverted_index.registry | 60 |
| abstract_inverted_index.relative | 139 |
| abstract_inverted_index.reported | 85 |
| abstract_inverted_index.Adjusting | 160 |
| abstract_inverted_index.Americans | 173 |
| abstract_inverted_index.Epidemiol | 237 |
| abstract_inverted_index.activity, | 94, 204 |
| abstract_inverted_index.adjusting | 130 |
| abstract_inverted_index.clinical, | 25 |
| abstract_inverted_index.comprised | 110 |
| abstract_inverted_index.decreased | 164 |
| abstract_inverted_index.disparity | 2, 103, 165, 233 |
| abstract_inverted_index.influence | 211 |
| abstract_inverted_index.interview | 50 |
| abstract_inverted_index.lifestyle | 28 |
| abstract_inverted_index.mortality | 6, 38, 220 |
| abstract_inverted_index.primarily | 166 |
| abstract_inverted_index.variables | 81, 99, 163, 180, 195, 209 |
| abstract_inverted_index.1064–72. | 241 |
| abstract_inverted_index.Americans, | 120, 154, 158 |
| abstract_inverted_index.Americans. | 126 |
| abstract_inverted_index.Biomarkers | 238 |
| abstract_inverted_index.California | 44 |
| abstract_inverted_index.Consortium | 48 |
| abstract_inverted_index.Fifty-four | 113 |
| abstract_inverted_index.accounting | 17 |
| abstract_inverted_index.additional | 91 |
| abstract_inverted_index.associated | 34 |
| abstract_inverted_index.contextual | 30 |
| abstract_inverted_index.diagnosis. | 193 |
| abstract_inverted_index.mortality, | 214 |
| abstract_inverted_index.mortality. | 235 |
| abstract_inverted_index.negligible | 197 |
| abstract_inverted_index.non-Latina | 116 |
| abstract_inverted_index.prevalence | 23 |
| abstract_inverted_index.previously | 84 |
| abstract_inverted_index.regression | 87 |
| abstract_inverted_index.comorbidity | 98, 208 |
| abstract_inverted_index.contextual, | 92, 202 |
| abstract_inverted_index.differences | 20 |
| abstract_inverted_index.documented. | 13 |
| abstract_inverted_index.influential | 179 |
| abstract_inverted_index.Survivorship | 47 |
| abstract_inverted_index.contribution | 79 |
| abstract_inverted_index.investigated | 226 |
| abstract_inverted_index.neighborhood | 186 |
| abstract_inverted_index.(0.33–0.85) | 151 |
| abstract_inverted_index.1.46–1.96), | 146 |
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| abstract_inverted_index.racial/ethnic | 19, 102, 219, 232 |
| abstract_inverted_index.respectively. | 159 |
| abstract_inverted_index.socioeconomic | 187 |
| abstract_inverted_index.(0.84–1.19), | 148 |
| abstract_inverted_index.(0.96–1.33). | 176 |
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| abstract_inverted_index.<i>Cancer | 236 |
| abstract_inverted_index.California-based | 54 |
| abstract_inverted_index.characteristics, | 185 |
| abstract_inverted_index.cancer–specific | 5, 37, 106, 137, 213 |
| abstract_inverted_index.AACR</i>.</p></div> | 243 |
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| abstract_inverted_index.disparity.</p><p><b>Methods:</b> | 42 |
| abstract_inverted_index.mortality.</p><p><b>Results:</b> | 107 |
| abstract_inverted_index.<div>Abstract<p><b>Background:</b> | 0 |
| abstract_inverted_index.disparity.</p><p><b>Conclusions:</b> | 200 |
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| countries_distinct_count | 0 |
| institutions_distinct_count | 16 |
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