Deceased organ donor factors influencing pancreatic graft transplantation and survival Article Swipe
Mitchell B. Sally
,
Margaret K. Menzel Ellis
,
Michael P. Hutchens
,
Tahnee Groat
,
Elizabeth A. Swanson
,
Madhukar S. Patel
,
Claus U. Niemann
,
Darren Malinoski
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1111/ctr.13571
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1111/ctr.13571
Criteria for organ acceptance in brain‐dead organ donors remain inconsistent, especially when concerning pancreatic transplants. We sought to examine donor‐specific predictors of pancreatic graft use and survival to better guide the selection and management of potential donors. A prospective observational study of all donors from ten organ procurement organizations was conducted from March 2012 to January 2015. Critical care endpoints were collected at 4 standardized time points. Data associated with pancreatic transplantation and graft survival rates were first determined using univariate analyses, and then logistic regression was used to identify independent predictors of these two outcomes. From 1819 donors, 238 (13.1%) pancreata were transplanted, and at a mean follow‐up of 192 days, 218 (91.6%) grafts had survived. After regression analysis, donor age (OR = 0.89), HgbA1C (OR = 0.07), and achieving the donor management goal (DMG) for ejection fraction at allocation of ≥50% (OR = 3.29) remained as independent predictors of pancreatic utilization. On regression analysis, graft survival was independently predicted by lower donor age (OR = 0.93) and achieving the DMGs for mean arterial pressure (60‐110 mm Hg) and glucose (≤180 mg/dL) at separate time points. These results may help guide the management and selection of potential pancreatic donors after brain death.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/ctr.13571
- OA Status
- green
- Cited By
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- References
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W2937118925Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/ctr.13571Digital Object Identifier
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Deceased organ donor factors influencing pancreatic graft transplantation and survivalWork title
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articleOpenAlex work type
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enPrimary language
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2019Year of publication
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2019-04-19Full publication date if available
- Authors
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Mitchell B. Sally, Margaret K. Menzel Ellis, Michael P. Hutchens, Tahnee Groat, Elizabeth A. Swanson, Madhukar S. Patel, Claus U. Niemann, Darren MalinoskiList of authors in order
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https://doi.org/10.1111/ctr.13571Publisher landing page
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
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https://www.ncbi.nlm.nih.gov/pmc/articles/8034871Direct OA link when available
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Medicine, Logistic regression, Transplantation, Univariate analysis, Organ donation, Internal medicine, Observational study, Organ procurement, Surgery, Multivariate analysisTop concepts (fields/topics) attached by OpenAlex
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10Total citation count in OpenAlex
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2025: 1, 2023: 1, 2022: 1, 2021: 6, 2020: 1Per-year citation counts (last 5 years)
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29Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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