Deprescribing Leads to Improved Energy Intake among Hospitalized Older Sarcopenic Adults with Polypharmacy after Stroke Article Swipe
Ayaka Matsumoto
,
Yoshihiro Yoshimura
,
Hidetaka Wakabayashi
,
Eiji Kose
,
Fumihiko Nagano
,
Takahiro Bise
,
Yoshifumi Kido
,
Sayuri Shimazu
,
Ai Shiraishi
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/nu14030443
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/nu14030443
Evidence is scarce regarding the polypharmacy in patients with sarcopenia. The aim of this study was to investigate the effect of deprescribing for polypharmacy on the improvement of nutritional intake and sarcopenia in older patients with sarcopenia. A retrospective cohort study was conducted with hospitalized older patients with sarcopenia undergoing rehabilitation after stroke. Study outcomes included energy intake, protein intake, handgrip strength (HG) and skeletal muscle mass index (SMI) at hospital discharge. To consider the effects of deprescribing for polypharmacy, we used multivariate analyses to examine whether the change in the number of medications during hospitalization was associated with outcomes. Of 361 patients after enrollment, 91 (mean age 81.0 years, 48.4% male) presented with sarcopenia and polypharmacy and were eligible for analysis. The change in the number of medications was independently associated with energy intake (β = −0.237, p = 0.009) and protein intake (β = −0.242, p = 0.047) at discharge, and was not statistically significantly associated with HG (β = −0.018, p = 0.768) and SMI (β = 0.083, p = 0.265) at discharge, respectively. Deprescribing was associated with improved nutritional intake in older sarcopenic patients with polypharmacy undergoing stroke rehabilitation.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/nu14030443
- https://www.mdpi.com/2072-6643/14/3/443/pdf?version=1642595990
- OA Status
- gold
- Cited By
- 39
- References
- 36
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4205966226
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4205966226Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/nu14030443Digital Object Identifier
- Title
-
Deprescribing Leads to Improved Energy Intake among Hospitalized Older Sarcopenic Adults with Polypharmacy after StrokeWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-01-19Full publication date if available
- Authors
-
Ayaka Matsumoto, Yoshihiro Yoshimura, Hidetaka Wakabayashi, Eiji Kose, Fumihiko Nagano, Takahiro Bise, Yoshifumi Kido, Sayuri Shimazu, Ai ShiraishiList of authors in order
- Landing page
-
https://doi.org/10.3390/nu14030443Publisher landing page
- PDF URL
-
https://www.mdpi.com/2072-6643/14/3/443/pdf?version=1642595990Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.mdpi.com/2072-6643/14/3/443/pdf?version=1642595990Direct OA link when available
- Concepts
-
Polypharmacy, Sarcopenia, Deprescribing, Medicine, Retrospective cohort study, Stroke (engine), Physical therapy, Rehabilitation, Internal medicine, Comorbidity, Body mass index, Gerontology, Mechanical engineering, EngineeringTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
39Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 9, 2024: 7, 2023: 8, 2022: 15Per-year citation counts (last 5 years)
- References (count)
-
36Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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