Description of Gastric Acidity (pH) with Simple Method in Lipopolysaccharide Induced Mice Article Swipe
Anna Surgean Veterini
,
Bambang Wahjuprajitno
,
Nancy Margarita Rehatta
,
Heni Rachmawati
,
Subijanto Marto Soedarmo
,
I Ketut Sudiana
,
Widodo J. Pudjirahardjo
,
Annis Catur Adi
,
Rachmad Suhanda
,
Sarmanu Sarmanu
,
Widjiati Widjiati
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.19087/jveteriner.2023.24.1.55
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.19087/jveteriner.2023.24.1.55
The gastrointestinal acidity/pH can considerably influence the stability and absorption of oral medications. As a result, understanding the circumstances for drug delivery requires knowledge of gastrointestinal pH. Mice injected with lipopolysaccharide (LPS) are used in the most well-studied animal models of sepsis. However, information on gastrointestinal pH in sepsis mice is still insufficient. This study was conducted to identify gastric pH values in mice induced by lipopolysaccharide. The LPS was injected intraperitoneally as well as 0.9% NaCl as control groups. Treated groups (LPS) consisted of four groups and the control group (0.9% NaCl) consisted of four groups. Ten mice were used in each group. Gastric pH measurement was conducted using pH meter Lutron PH-201. Based on this study, the factors that influenced gastric pH in sepsis animal models were the LPS doses and the time after LPS injection. The results of gastric pH measurement in sepsis mice did not show a decrease in the pH compared to the normal conditions. The dose of LPS significantly influences the gastric pH change.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.19087/jveteriner.2023.24.1.55
- https://ojs.unud.ac.id/index.php/jvet/article/download/79503/51200
- OA Status
- gold
- Cited By
- 1
- References
- 39
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4387097427
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4387097427Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.19087/jveteriner.2023.24.1.55Digital Object Identifier
- Title
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Description of Gastric Acidity (pH) with Simple Method in Lipopolysaccharide Induced MiceWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
-
2023-03-31Full publication date if available
- Authors
-
Anna Surgean Veterini, Bambang Wahjuprajitno, Nancy Margarita Rehatta, Heni Rachmawati, Subijanto Marto Soedarmo, I Ketut Sudiana, Widodo J. Pudjirahardjo, Annis Catur Adi, Rachmad Suhanda, Sarmanu Sarmanu, Widjiati WidjiatiList of authors in order
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https://doi.org/10.19087/jveteriner.2023.24.1.55Publisher landing page
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https://ojs.unud.ac.id/index.php/jvet/article/download/79503/51200Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://ojs.unud.ac.id/index.php/jvet/article/download/79503/51200Direct OA link when available
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Lipopolysaccharide, Sepsis, Chemistry, Pharmacology, Internal medicine, Gastroenterology, MedicineTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2024: 1Per-year citation counts (last 5 years)
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39Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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