DESIGN AND DEVELOPMENT OF CARBOXYMETHYL CHITOSAN- HPMC MATRICES OF VERAPAMIL HCL CAPSULE Article Swipe
Dinesh Pratap Singh
,
And Kumar M
,
Mr Kumar
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.31032/ijbpas/2023/12.5.7150
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.31032/ijbpas/2023/12.5.7150
Aim of the study was to find out the potential of HPMC-based polymeric matrices formulation such as carriers for gastrointestinal tract targeted drug therapy of verapamil hydrochloride capsule formulation.Prepared single-unit hydrodynamically balanced (HBS) capsule formulations by the encapsulation using hard gelatin capsules technique properly mix all the physical mixtures of various drug polymers such as HPMC, K4M and Carboxymethyl Chitosan.At the time of In-vitro study in 0.1M HCL shows good floating time (5-10 hr) and drug release profile were carried out using 0.1M HCL as a dissolution medium.Finally prepared HPMCbased polymeric matrices formulation was very helpful for gastrointestinal tract delivery.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.31032/ijbpas/2023/12.5.7150
- https://doi.org/10.31032/ijbpas/2023/12.5.7150
- OA Status
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- OpenAlex ID
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All OpenAlex metadata
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https://openalex.org/W4367400081Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.31032/ijbpas/2023/12.5.7150Digital Object Identifier
- Title
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DESIGN AND DEVELOPMENT OF CARBOXYMETHYL CHITOSAN- HPMC MATRICES OF VERAPAMIL HCL CAPSULEWork title
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articleOpenAlex work type
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-04-29Full publication date if available
- Authors
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Dinesh Pratap Singh, And Kumar M, Mr KumarList of authors in order
- Landing page
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https://doi.org/10.31032/ijbpas/2023/12.5.7150Publisher landing page
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https://doi.org/10.31032/ijbpas/2023/12.5.7150Direct link to full text PDF
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://doi.org/10.31032/ijbpas/2023/12.5.7150Direct OA link when available
- Concepts
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Capsule, Chitosan, Chemistry, Carboxymethyl cellulose, Materials science, Organic chemistry, Sodium, Geology, PaleontologyTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
- References (count)
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22Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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