Design of perfused PTFE vessel-like constructs for in vitro applications Article Swipe

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In vitro Materials science Biomedical engineering Chemistry Engineering Biochemistry

Manuela Estermann , Giovanni Spiaggia , Dedy Septiadi , Irini M. Dijkhoff , Barbara Drašler , Alke Petri‐Fink , Barbara Rothen‐Rutishauser ·

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YOU? · · 2021 · Open Access · · DOI: https://doi.org/10.5281/zenodo.4434538 · OA: W4393760526

The design of a vessel-like construct for further use in perfused tissue models using PTFE membranes and collagen is presented. Endothelial cells were able to adhere to the tube’s wall, resisted perfusion, and formed an endothelial barrier delaying diffusion of fluorescently labeled molecules.

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