Designing and Implementing a Privacy Preserving Record Linkage Protocol Article Swipe
YOU?
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· 2018
· Open Access
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· DOI: https://doi.org/10.23889/ijpds.v3i4.831
IntroductionThe Ontario Brain Institute has developed Brain-CODE, an informatics platform, to support the acquisition, storage, management and analysis of multi-modal data. The standardized research data within Brain-CODE spans several brain disorders, allowing for integrative analyses, while also providing the opportunity to leverage existing clinical administrative data holdings through external linkages. Objectives and ApproachWithin Ontario, the majority of individuals who access the healthcare system have a unique identifier, the Ontario Health Insurance Plan (OHIP) number. The OHIP number can facilitate linkages with administrative data holdings, such as those at the Institute for Clinical Evaluative Sciences (ICES). Given that OBI is not permitted under Ontario’s privacy legislation to hold OHIP numbers, identifiers for consented participants are encrypted using a public key mechanism upon entry into Brain-CODE, where the private key is inaccessible. To facilitate linkages involving OHIP numbers between Brain-CODE and ICES, Brain-CODE Link software was co-developed by members of the Indoc Consortium. ResultsBrain-CODE Link allows a deterministic linkage between encrypted identifiers (OHIP numbers), without revealing participant identity. The same homomorphic encryption algorithm applied to identifiers upon entry to Brain-CODE, is applied to relevant identifiers within ICES data holdings. Encrypted identifiers from Brain-CODE are securely transferred to ICES, where a comparison computation calculates differences between the encrypted sets. These differences are sent to a semi-trusted third party, who has no access to the original data, to decrypt the differences using the private key. A zero difference indicates a set of matching identifiers. One of the main challenges during testing and development of Brain-CODE Link was ensuring the software was capable of scaling to a population level, performing a large number of comparisons, in a computationally efficient manner. Conclusion/ImplicationsOngoing pilot projects within the areas of epilepsy, neurodevelopment disorders, and neurodegeneration will be the first examples of linkages between Brain-CODE and ICES. Brain-CODE Link has successfully performed several billion test comparisons, indicating its suitability to function as a scalable privacy preserving record linkage to support comprehensive analyses.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.23889/ijpds.v3i4.831
- https://ijpds.org/article/download/831/748
- OA Status
- gold
- Cited By
- 2
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2890888398
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2890888398Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.23889/ijpds.v3i4.831Digital Object Identifier
- Title
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Designing and Implementing a Privacy Preserving Record Linkage ProtocolWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2018Year of publication
- Publication date
-
2018-09-03Full publication date if available
- Authors
-
Tom Gee, Brendan Behan, Shannon Lefaivre, Mahmoud Azimaee, Moyez Dharsee, Khaled El Emam, Julie Yang, Anthony L. Vaccarino, Kenneth Evans, J. Charles Victor, Elizabeth TheriaultList of authors in order
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https://doi.org/10.23889/ijpds.v3i4.831Publisher landing page
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https://ijpds.org/article/download/831/748Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://ijpds.org/article/download/831/748Direct OA link when available
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Identifier, Computer science, Encryption, Unique identifier, Computer security, Code (set theory), Source code, Internet privacy, Set (abstract data type), Computer network, Programming language, Operating systemTop concepts (fields/topics) attached by OpenAlex
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2Total citation count in OpenAlex
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2023: 1, 2022: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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