Detección del virus del papiloma humano en biopsias de cancer de mama mediante PCR e inmunohistoquimica en el Hospital Santa Rosa durante el 2019 Article Swipe
Enrique Mamani
,
Meyling Vilcapoma-Diaz
,
Nazario Ortiz-Muchotrigo
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.17843/rpmesp.2022.394.11069
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.17843/rpmesp.2022.394.11069
El objetivo de este estudio fue determinar la presencia del Virus Papiloma Humano (VPH) tipo 16 y 18 en biopsias de tejido mamario parafinado de pacientes con diagnóstico clínico de cáncer de mama. Se analizaron 32 biopsias de cáncer de mama embebidas en parafina para detectar el ADN de VPH mediante PCR en tiempo real, los iniciadores estuvieron dirigidos al gen E6. Se evaluaron el tipo histológico, grado histológico y la sobreexpresión de C-erB2 y Ki-67 mediante inmunohistoquímica. El 84,38% (27) fueron positivos para VPH, el 25% (8) fueron positivos para VPH-16 y el 59,38% (19) para VPH-18. El 15,63% (5) de las muestras presentaron infección mixta. Se evidenció la sobrexpresión de C-erbB2 y Ki-67 en 6,25% (2) de las muestras positivas para VPH-16 y 15,63% (5) de las muestras positivas para VPH-18. Se detectó ADN de VPH-16 y VPH-18 en las muestras de biopsias analizadas mediante PCR en tiempo real.
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Metadata
- Type
- article
- Language
- es
- Landing Page
- https://doi.org/10.17843/rpmesp.2022.394.11069
- https://rpmesp.ins.gob.pe/index.php/rpmesp/article/download/11069/5160
- OA Status
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4313889091Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.17843/rpmesp.2022.394.11069Digital Object Identifier
- Title
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Detección del virus del papiloma humano en biopsias de cancer de mama mediante PCR e inmunohistoquimica en el Hospital Santa Rosa durante el 2019Work title
- Type
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articleOpenAlex work type
- Language
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esPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-12-15Full publication date if available
- Authors
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Enrique Mamani, Meyling Vilcapoma-Diaz, Nazario Ortiz-MuchotrigoList of authors in order
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https://doi.org/10.17843/rpmesp.2022.394.11069Publisher landing page
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https://rpmesp.ins.gob.pe/index.php/rpmesp/article/download/11069/5160Direct link to full text PDF
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://rpmesp.ins.gob.pe/index.php/rpmesp/article/download/11069/5160Direct OA link when available
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Medicine, Molecular biology, Art, BiologyTop concepts (fields/topics) attached by OpenAlex
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2Total citation count in OpenAlex
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2024: 2Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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