Detecting Pain Correlates With Recovery in Acute Brain Injury Patients With Disorders of Consciousness Article Swipe
Julia Houshmand
,
Brian Manolovitz
,
Kelsey E. Ladd
,
Danielle Bass
,
Elena Mishkovsky
,
Ana Bolaños Saavedra
,
Fernanda J.P. Teixeira
,
David Monroy
,
Esther Monexe
,
Tulay Koru‐Sengul
,
Linda E. Robayo
,
Kristiina Kinnunen
,
Lee K. Hong
,
John A McKeown
,
Nina Massad
,
Mohan Kottapally
,
Amedeo Merenda
,
Kristine O’Phelan
,
Ayham Alkhachroum
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1097/cce.0000000000001323
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1097/cce.0000000000001323
OBJECTIVES: To evaluate pain as measured by the critical care pain observation tool (CPOT) and its potential as a biomarker for recovery in acute brain injury (ABI) patients with disorders of consciousness (DoC). DESIGN: Prospective observational single-center study. SETTING: Neuroscience ICU 2020–2024. PATIENTS: ABI patients with DoC. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Data included demographic, clinical characteristics, and CPOT scores. Glasgow Outcome Scale-Extended (GOSE) was obtained at 3, 6, and 12 months. Descriptive statistics, correlation coefficients, and logistic regression models were calculated to assess relationships between pain and GOSE. Of 110 patients, 62 (56%) had traumatic brain injury, 45 (41%) intracerebral hemorrhage, and 3 (3%) subarachnoid hemorrhage. Average age was 50 ± 18 years old, 76% males, and 69% White. A total of 27 patients (25%) experienced less than 5% of moderate/severe pain burden, 83 (75%) experienced greater than or equal to 5%, 59 (54%) greater than or equal to 10%, 36 (33%) greater than or equal to 15%, and 17 (16%) greater than or equal to 20%. We found on average two to three times higher odds of consciousness recovery (GOSE ≥ 3) and functional recovery (GOSE ≥ 4) at 12 months in patients who experience a higher burden of pain. The association with outcomes remained even after adjusting for age, Glasgow Coma Scale at admission, and sedation levels. Moderate/severe burden levels correlated positively with consciousness recovery ( r = 0.23; p < 0.05), functional recovery ( r = 0.2; p < 0.05), and the sliding dichotomy of GOSE, tailoring outcomes according to baseline severity ( r = 0.43; p < 0.05) at 12-month follow-up and across all time points, whereas no pain levels correlated negatively across outcomes and time points. CONCLUSIONS: Pain as evaluated by a commonly used score in the ICU (CPOT score) is common and its burden correlated consciousness and functional recovery at 3, 6, and 12 months in ABI patients with DoC.
Related Topics
Concepts
No concepts available.
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1097/cce.0000000000001323
- OA Status
- gold
- References
- 44
- OpenAlex ID
- https://openalex.org/W4414462229
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4414462229Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1097/cce.0000000000001323Digital Object Identifier
- Title
-
Detecting Pain Correlates With Recovery in Acute Brain Injury Patients With Disorders of ConsciousnessWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-09-24Full publication date if available
- Authors
-
Julia Houshmand, Brian Manolovitz, Kelsey E. Ladd, Danielle Bass, Elena Mishkovsky, Ana Bolaños Saavedra, Fernanda J.P. Teixeira, David Monroy, Esther Monexe, Tulay Koru‐Sengul, Linda E. Robayo, Kristiina Kinnunen, Lee K. Hong, John A McKeown, Nina Massad, Mohan Kottapally, Amedeo Merenda, Kristine O’Phelan, Ayham AlkhachroumList of authors in order
- Landing page
-
https://doi.org/10.1097/cce.0000000000001323Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1097/cce.0000000000001323Direct OA link when available
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
44Number of works referenced by this work
Full payload
| id | https://openalex.org/W4414462229 |
|---|---|
| doi | https://doi.org/10.1097/cce.0000000000001323 |
| ids.doi | https://doi.org/10.1097/cce.0000000000001323 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/40991684 |
| ids.openalex | https://openalex.org/W4414462229 |
| fwci | 0.0 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D006801 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Humans |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D008297 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | Male |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D005260 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Female |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D008875 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Middle Aged |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D011446 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Prospective Studies |
| mesh[5].qualifier_ui | Q000209 |
| mesh[5].descriptor_ui | D003244 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | etiology |
| mesh[5].descriptor_name | Consciousness Disorders |
| mesh[6].qualifier_ui | Q000150 |
| mesh[6].descriptor_ui | D003244 |
| mesh[6].is_major_topic | True |
| mesh[6].qualifier_name | complications |
| mesh[6].descriptor_name | Consciousness Disorders |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D000328 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Adult |
| mesh[8].qualifier_ui | Q000379 |
| mesh[8].descriptor_ui | D010147 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | methods |
| mesh[8].descriptor_name | Pain Measurement |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D023261 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Glasgow Outcome Scale |
| mesh[10].qualifier_ui | Q000150 |
| mesh[10].descriptor_ui | D001930 |
| mesh[10].is_major_topic | True |
| mesh[10].qualifier_name | complications |
| mesh[10].descriptor_name | Brain Injuries |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D020127 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Recovery of Function |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D000368 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Aged |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D007362 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Intensive Care Units |
| mesh[14].qualifier_ui | Q000175 |
| mesh[14].descriptor_ui | D010146 |
| mesh[14].is_major_topic | True |
| mesh[14].qualifier_name | diagnosis |
| mesh[14].descriptor_name | Pain |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D006801 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Humans |
| mesh[16].qualifier_ui | |
| mesh[16].descriptor_ui | D008297 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | |
| mesh[16].descriptor_name | Male |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D005260 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Female |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D008875 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Middle Aged |
| mesh[19].qualifier_ui | |
| mesh[19].descriptor_ui | D011446 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | |
| mesh[19].descriptor_name | Prospective Studies |
| mesh[20].qualifier_ui | Q000209 |
| mesh[20].descriptor_ui | D003244 |
| mesh[20].is_major_topic | True |
| mesh[20].qualifier_name | etiology |
| mesh[20].descriptor_name | Consciousness Disorders |
| mesh[21].qualifier_ui | Q000150 |
| mesh[21].descriptor_ui | D003244 |
| mesh[21].is_major_topic | True |
| mesh[21].qualifier_name | complications |
| mesh[21].descriptor_name | Consciousness Disorders |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D000328 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Adult |
| mesh[23].qualifier_ui | Q000379 |
| mesh[23].descriptor_ui | D010147 |
| mesh[23].is_major_topic | True |
| mesh[23].qualifier_name | methods |
| mesh[23].descriptor_name | Pain Measurement |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D023261 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Glasgow Outcome Scale |
| mesh[25].qualifier_ui | Q000150 |
| mesh[25].descriptor_ui | D001930 |
| mesh[25].is_major_topic | True |
| mesh[25].qualifier_name | complications |
| mesh[25].descriptor_name | Brain Injuries |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D020127 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Recovery of Function |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D000368 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Aged |
| mesh[28].qualifier_ui | |
| mesh[28].descriptor_ui | D007362 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | |
| mesh[28].descriptor_name | Intensive Care Units |
| mesh[29].qualifier_ui | Q000175 |
| mesh[29].descriptor_ui | D010146 |
| mesh[29].is_major_topic | True |
| mesh[29].qualifier_name | diagnosis |
| mesh[29].descriptor_name | Pain |
| mesh[30].qualifier_ui | |
| mesh[30].descriptor_ui | D006801 |
| mesh[30].is_major_topic | False |
| mesh[30].qualifier_name | |
| mesh[30].descriptor_name | Humans |
| mesh[31].qualifier_ui | |
| mesh[31].descriptor_ui | D008297 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | |
| mesh[31].descriptor_name | Male |
| mesh[32].qualifier_ui | |
| mesh[32].descriptor_ui | D005260 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | |
| mesh[32].descriptor_name | Female |
| mesh[33].qualifier_ui | |
| mesh[33].descriptor_ui | D008875 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | |
| mesh[33].descriptor_name | Middle Aged |
| mesh[34].qualifier_ui | |
| mesh[34].descriptor_ui | D011446 |
| mesh[34].is_major_topic | False |
| mesh[34].qualifier_name | |
| mesh[34].descriptor_name | Prospective Studies |
| mesh[35].qualifier_ui | Q000209 |
| mesh[35].descriptor_ui | D003244 |
| mesh[35].is_major_topic | True |
| mesh[35].qualifier_name | etiology |
| mesh[35].descriptor_name | Consciousness Disorders |
| mesh[36].qualifier_ui | Q000150 |
| mesh[36].descriptor_ui | D003244 |
| mesh[36].is_major_topic | True |
| mesh[36].qualifier_name | complications |
| mesh[36].descriptor_name | Consciousness Disorders |
| mesh[37].qualifier_ui | |
| mesh[37].descriptor_ui | D000328 |
| mesh[37].is_major_topic | False |
| mesh[37].qualifier_name | |
| mesh[37].descriptor_name | Adult |
| mesh[38].qualifier_ui | Q000379 |
| mesh[38].descriptor_ui | D010147 |
| mesh[38].is_major_topic | True |
| mesh[38].qualifier_name | methods |
| mesh[38].descriptor_name | Pain Measurement |
| mesh[39].qualifier_ui | |
| mesh[39].descriptor_ui | D023261 |
| mesh[39].is_major_topic | False |
| mesh[39].qualifier_name | |
| mesh[39].descriptor_name | Glasgow Outcome Scale |
| mesh[40].qualifier_ui | Q000150 |
| mesh[40].descriptor_ui | D001930 |
| mesh[40].is_major_topic | True |
| mesh[40].qualifier_name | complications |
| mesh[40].descriptor_name | Brain Injuries |
| mesh[41].qualifier_ui | |
| mesh[41].descriptor_ui | D020127 |
| mesh[41].is_major_topic | False |
| mesh[41].qualifier_name | |
| mesh[41].descriptor_name | Recovery of Function |
| mesh[42].qualifier_ui | |
| mesh[42].descriptor_ui | D000368 |
| mesh[42].is_major_topic | False |
| mesh[42].qualifier_name | |
| mesh[42].descriptor_name | Aged |
| mesh[43].qualifier_ui | |
| mesh[43].descriptor_ui | D007362 |
| mesh[43].is_major_topic | False |
| mesh[43].qualifier_name | |
| mesh[43].descriptor_name | Intensive Care Units |
| mesh[44].qualifier_ui | Q000175 |
| mesh[44].descriptor_ui | D010146 |
| mesh[44].is_major_topic | True |
| mesh[44].qualifier_name | diagnosis |
| mesh[44].descriptor_name | Pain |
| type | article |
| title | Detecting Pain Correlates With Recovery in Acute Brain Injury Patients With Disorders of Consciousness |
| biblio.issue | 10 |
| biblio.volume | 7 |
| biblio.last_page | e1323 |
| biblio.first_page | e1323 |
| topics[0].id | https://openalex.org/T10645 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9998999834060669 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2711 |
| topics[0].subfield.display_name | Emergency Medicine |
| topics[0].display_name | Cardiac Arrest and Resuscitation |
| topics[1].id | https://openalex.org/T10706 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9995999932289124 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2728 |
| topics[1].subfield.display_name | Neurology |
| topics[1].display_name | Traumatic Brain Injury and Neurovascular Disturbances |
| topics[2].id | https://openalex.org/T10416 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9994999766349792 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2713 |
| topics[2].subfield.display_name | Epidemiology |
| topics[2].display_name | Traumatic Brain Injury Research |
| is_xpac | False |
| apc_list.value | 1600 |
| apc_list.currency | USD |
| apc_list.value_usd | 1600 |
| apc_paid.value | 1600 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 1600 |
| language | en |
| locations[0].id | doi:10.1097/cce.0000000000001323 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S4210210302 |
| locations[0].source.issn | 2639-8028 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2639-8028 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Critical Care Explorations |
| locations[0].source.host_organization | https://openalex.org/P4310318547 |
| locations[0].source.host_organization_name | Wolters Kluwer |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310318547 |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Critical Care Explorations |
| locations[0].landing_page_url | https://doi.org/10.1097/cce.0000000000001323 |
| locations[1].id | pmid:40991684 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Critical care explorations |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/40991684 |
| locations[2].id | pmh:oai:doaj.org/article:b319e1288ce64585928730c79b131f72 |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].source.host_organization_lineage | |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Critical Care Explorations, Vol 7, Iss 10, p e1323 (2025) |
| locations[2].landing_page_url | https://doaj.org/article/b319e1288ce64585928730c79b131f72 |
| locations[3].id | pmh:oai:europepmc.org:11271602 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S4306400806 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | Europe PMC (PubMed Central) |
| locations[3].source.host_organization | https://openalex.org/I1303153112 |
| locations[3].source.host_organization_name | European Bioinformatics Institute |
| locations[3].source.host_organization_lineage | https://openalex.org/I1303153112 |
| locations[3].license | other-oa |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | https://openalex.org/licenses/other-oa |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | |
| locations[3].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/12463170 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5119714215 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Julia Houshmand |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I2802864460 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I145608581 |
| authorships[0].affiliations[1].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[0].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[0].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[0].institutions[0].type | healthcare |
| authorships[0].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[0].institutions[1].id | https://openalex.org/I145608581 |
| authorships[0].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[0].institutions[1].type | education |
| authorships[0].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[0].institutions[1].country_code | US |
| authorships[0].institutions[1].display_name | University of Miami |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Julia Houshmand |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[1].author.id | https://openalex.org/A5049292854 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Brian Manolovitz |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[1].institutions[0].id | https://openalex.org/I145608581 |
| authorships[1].institutions[0].ror | https://ror.org/02dgjyy92 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I145608581 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | University of Miami |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Brian Manolovitz |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[2].author.id | https://openalex.org/A5114352136 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Kelsey E. Ladd |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I2802864460 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[2].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[2].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Kelsey E. Ladd |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[3].author.id | https://openalex.org/A5091517734 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Danielle Bass |
| authorships[3].countries | US |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[3].affiliations[1].institution_ids | https://openalex.org/I2802864460 |
| authorships[3].affiliations[1].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[3].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[3].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[3].institutions[0].type | healthcare |
| authorships[3].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[3].institutions[0].country_code | US |
| authorships[3].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[3].institutions[1].id | https://openalex.org/I145608581 |
| authorships[3].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[3].institutions[1].type | education |
| authorships[3].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[3].institutions[1].country_code | US |
| authorships[3].institutions[1].display_name | University of Miami |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Danielle Bass |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[4].author.id | https://openalex.org/A5117063494 |
| authorships[4].author.orcid | |
| authorships[4].author.display_name | Elena Mishkovsky |
| authorships[4].countries | US |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I2802864460 |
| authorships[4].affiliations[1].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[4].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[4].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[4].institutions[0].type | healthcare |
| authorships[4].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[4].institutions[0].country_code | US |
| authorships[4].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[4].institutions[1].id | https://openalex.org/I145608581 |
| authorships[4].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[4].institutions[1].type | education |
| authorships[4].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[4].institutions[1].country_code | US |
| authorships[4].institutions[1].display_name | University of Miami |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Elena Mishkovsky |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[5].author.id | https://openalex.org/A5092695811 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Ana Bolaños Saavedra |
| authorships[5].countries | US |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I2802864460 |
| authorships[5].affiliations[0].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[5].affiliations[1].institution_ids | https://openalex.org/I145608581 |
| authorships[5].affiliations[1].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[5].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[5].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[5].institutions[0].type | healthcare |
| authorships[5].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[5].institutions[0].country_code | US |
| authorships[5].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[5].institutions[1].id | https://openalex.org/I145608581 |
| authorships[5].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[5].institutions[1].type | education |
| authorships[5].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[5].institutions[1].country_code | US |
| authorships[5].institutions[1].display_name | University of Miami |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Ana Bolaños Saavedra |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[6].author.id | https://openalex.org/A5033045994 |
| authorships[6].author.orcid | https://orcid.org/0000-0001-8646-9624 |
| authorships[6].author.display_name | Fernanda J.P. Teixeira |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I2802864460 |
| authorships[6].affiliations[0].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[6].affiliations[1].institution_ids | https://openalex.org/I145608581 |
| authorships[6].affiliations[1].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[6].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[6].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[6].institutions[0].type | healthcare |
| authorships[6].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[6].institutions[1].id | https://openalex.org/I145608581 |
| authorships[6].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[6].institutions[1].type | education |
| authorships[6].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[6].institutions[1].country_code | US |
| authorships[6].institutions[1].display_name | University of Miami |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Fernanda J. P. Teixeira |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[7].author.id | https://openalex.org/A5022848289 |
| authorships[7].author.orcid | https://orcid.org/0000-0003-3007-429X |
| authorships[7].author.display_name | David Monroy |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[7].affiliations[0].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[7].affiliations[1].institution_ids | https://openalex.org/I2802864460 |
| authorships[7].affiliations[1].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[7].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[7].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[7].institutions[0].type | healthcare |
| authorships[7].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[7].institutions[0].country_code | US |
| authorships[7].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[7].institutions[1].id | https://openalex.org/I145608581 |
| authorships[7].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[7].institutions[1].type | education |
| authorships[7].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[7].institutions[1].country_code | US |
| authorships[7].institutions[1].display_name | University of Miami |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | David Monroy |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[8].author.id | https://openalex.org/A5093832892 |
| authorships[8].author.orcid | |
| authorships[8].author.display_name | Esther Monexe |
| authorships[8].countries | US |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I2802864460 |
| authorships[8].affiliations[0].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[8].affiliations[1].institution_ids | https://openalex.org/I145608581 |
| authorships[8].affiliations[1].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[8].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[8].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[8].institutions[0].type | healthcare |
| authorships[8].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[8].institutions[0].country_code | US |
| authorships[8].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[8].institutions[1].id | https://openalex.org/I145608581 |
| authorships[8].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[8].institutions[1].type | education |
| authorships[8].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[8].institutions[1].country_code | US |
| authorships[8].institutions[1].display_name | University of Miami |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Esther Monexe |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[9].author.id | https://openalex.org/A5054943896 |
| authorships[9].author.orcid | https://orcid.org/0000-0003-0974-8405 |
| authorships[9].author.display_name | Tulay Koru‐Sengul |
| authorships[9].countries | US |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[9].affiliations[0].raw_affiliation_string | Miami Clinical and Translational Institute, University of Miami, Miami, FL. |
| authorships[9].institutions[0].id | https://openalex.org/I145608581 |
| authorships[9].institutions[0].ror | https://ror.org/02dgjyy92 |
| authorships[9].institutions[0].type | education |
| authorships[9].institutions[0].lineage | https://openalex.org/I145608581 |
| authorships[9].institutions[0].country_code | US |
| authorships[9].institutions[0].display_name | University of Miami |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Tulay Koru-Sengul |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Miami Clinical and Translational Institute, University of Miami, Miami, FL. |
| authorships[10].author.id | https://openalex.org/A5025276053 |
| authorships[10].author.orcid | https://orcid.org/0000-0002-5188-3486 |
| authorships[10].author.display_name | Linda E. Robayo |
| authorships[10].countries | US |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[10].affiliations[0].raw_affiliation_string | Department of Neuroscience, University of Miami, Miami, FL. |
| authorships[10].institutions[0].id | https://openalex.org/I145608581 |
| authorships[10].institutions[0].ror | https://ror.org/02dgjyy92 |
| authorships[10].institutions[0].type | education |
| authorships[10].institutions[0].lineage | https://openalex.org/I145608581 |
| authorships[10].institutions[0].country_code | US |
| authorships[10].institutions[0].display_name | University of Miami |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Linda E. Robayo |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Department of Neuroscience, University of Miami, Miami, FL. |
| authorships[11].author.id | https://openalex.org/A5071333533 |
| authorships[11].author.orcid | |
| authorships[11].author.display_name | Kristiina Kinnunen |
| authorships[11].countries | US |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[11].affiliations[0].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[11].institutions[0].id | https://openalex.org/I145608581 |
| authorships[11].institutions[0].ror | https://ror.org/02dgjyy92 |
| authorships[11].institutions[0].type | education |
| authorships[11].institutions[0].lineage | https://openalex.org/I145608581 |
| authorships[11].institutions[0].country_code | US |
| authorships[11].institutions[0].display_name | University of Miami |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Kristiina E. Kinnunen |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[12].author.id | https://openalex.org/A5014352382 |
| authorships[12].author.orcid | https://orcid.org/0000-0003-0002-8858 |
| authorships[12].author.display_name | Lee K. Hong |
| authorships[12].countries | US |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I2802864460 |
| authorships[12].affiliations[0].raw_affiliation_string | Neuroscience Intensive Care Unit, Jackson Memorial Hospital, Miami, FL. |
| authorships[12].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[12].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[12].institutions[0].type | healthcare |
| authorships[12].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[12].institutions[0].country_code | US |
| authorships[12].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Lee Fong Hong |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | Neuroscience Intensive Care Unit, Jackson Memorial Hospital, Miami, FL. |
| authorships[13].author.id | https://openalex.org/A5119714216 |
| authorships[13].author.orcid | |
| authorships[13].author.display_name | John A McKeown |
| authorships[13].countries | US |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[13].affiliations[0].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[13].institutions[0].id | https://openalex.org/I145608581 |
| authorships[13].institutions[0].ror | https://ror.org/02dgjyy92 |
| authorships[13].institutions[0].type | education |
| authorships[13].institutions[0].lineage | https://openalex.org/I145608581 |
| authorships[13].institutions[0].country_code | US |
| authorships[13].institutions[0].display_name | University of Miami |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | John McKeown |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[14].author.id | https://openalex.org/A5012276431 |
| authorships[14].author.orcid | |
| authorships[14].author.display_name | Nina Massad |
| authorships[14].countries | US |
| authorships[14].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[14].affiliations[0].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[14].affiliations[1].institution_ids | https://openalex.org/I2802864460 |
| authorships[14].affiliations[1].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[14].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[14].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[14].institutions[0].type | healthcare |
| authorships[14].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[14].institutions[0].country_code | US |
| authorships[14].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[14].institutions[1].id | https://openalex.org/I145608581 |
| authorships[14].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[14].institutions[1].type | education |
| authorships[14].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[14].institutions[1].country_code | US |
| authorships[14].institutions[1].display_name | University of Miami |
| authorships[14].author_position | middle |
| authorships[14].raw_author_name | Nina Massad |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[15].author.id | https://openalex.org/A5043218738 |
| authorships[15].author.orcid | https://orcid.org/0000-0003-4377-2409 |
| authorships[15].author.display_name | Mohan Kottapally |
| authorships[15].countries | US |
| authorships[15].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[15].affiliations[0].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[15].affiliations[1].institution_ids | https://openalex.org/I2802864460 |
| authorships[15].affiliations[1].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[15].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[15].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[15].institutions[0].type | healthcare |
| authorships[15].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[15].institutions[0].country_code | US |
| authorships[15].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[15].institutions[1].id | https://openalex.org/I145608581 |
| authorships[15].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[15].institutions[1].type | education |
| authorships[15].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[15].institutions[1].country_code | US |
| authorships[15].institutions[1].display_name | University of Miami |
| authorships[15].author_position | middle |
| authorships[15].raw_author_name | Mohan Kottapally |
| authorships[15].is_corresponding | False |
| authorships[15].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[16].author.id | https://openalex.org/A5040231913 |
| authorships[16].author.orcid | https://orcid.org/0000-0002-9270-7470 |
| authorships[16].author.display_name | Amedeo Merenda |
| authorships[16].countries | US |
| authorships[16].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[16].affiliations[0].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[16].affiliations[1].institution_ids | https://openalex.org/I2802864460 |
| authorships[16].affiliations[1].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[16].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[16].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[16].institutions[0].type | healthcare |
| authorships[16].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[16].institutions[0].country_code | US |
| authorships[16].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[16].institutions[1].id | https://openalex.org/I145608581 |
| authorships[16].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[16].institutions[1].type | education |
| authorships[16].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[16].institutions[1].country_code | US |
| authorships[16].institutions[1].display_name | University of Miami |
| authorships[16].author_position | middle |
| authorships[16].raw_author_name | Amedeo Merenda |
| authorships[16].is_corresponding | False |
| authorships[16].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[17].author.id | https://openalex.org/A5111831046 |
| authorships[17].author.orcid | |
| authorships[17].author.display_name | Kristine O’Phelan |
| authorships[17].countries | US |
| authorships[17].affiliations[0].institution_ids | https://openalex.org/I2802864460 |
| authorships[17].affiliations[0].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[17].affiliations[1].institution_ids | https://openalex.org/I145608581 |
| authorships[17].affiliations[1].raw_affiliation_string | Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[17].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[17].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[17].institutions[0].type | healthcare |
| authorships[17].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[17].institutions[0].country_code | US |
| authorships[17].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[17].institutions[1].id | https://openalex.org/I145608581 |
| authorships[17].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[17].institutions[1].type | education |
| authorships[17].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[17].institutions[1].country_code | US |
| authorships[17].institutions[1].display_name | University of Miami |
| authorships[17].author_position | middle |
| authorships[17].raw_author_name | Kristine O’Phelan |
| authorships[17].is_corresponding | False |
| authorships[17].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Department of Neurology, University of Miami Miller School of Medicine, Miami, FL. |
| authorships[18].author.id | https://openalex.org/A5047790773 |
| authorships[18].author.orcid | https://orcid.org/0000-0003-0352-5913 |
| authorships[18].author.display_name | Ayham Alkhachroum |
| authorships[18].countries | US |
| authorships[18].affiliations[0].institution_ids | https://openalex.org/I145608581 |
| authorships[18].affiliations[0].raw_affiliation_string | Miami Clinical and Translational Institute, University of Miami, Miami, FL. |
| authorships[18].affiliations[1].institution_ids | https://openalex.org/I2802864460 |
| authorships[18].affiliations[1].raw_affiliation_string | Department of Neurology, Jackson Memorial Hospital, Miami, FL. |
| authorships[18].institutions[0].id | https://openalex.org/I2802864460 |
| authorships[18].institutions[0].ror | https://ror.org/02y070a55 |
| authorships[18].institutions[0].type | healthcare |
| authorships[18].institutions[0].lineage | https://openalex.org/I2802864460, https://openalex.org/I4210089954 |
| authorships[18].institutions[0].country_code | US |
| authorships[18].institutions[0].display_name | Jackson Memorial Hospital |
| authorships[18].institutions[1].id | https://openalex.org/I145608581 |
| authorships[18].institutions[1].ror | https://ror.org/02dgjyy92 |
| authorships[18].institutions[1].type | education |
| authorships[18].institutions[1].lineage | https://openalex.org/I145608581 |
| authorships[18].institutions[1].country_code | US |
| authorships[18].institutions[1].display_name | University of Miami |
| authorships[18].author_position | last |
| authorships[18].raw_author_name | Ayham Alkhachroum |
| authorships[18].is_corresponding | False |
| authorships[18].raw_affiliation_strings | Department of Neurology, Jackson Memorial Hospital, Miami, FL., Miami Clinical and Translational Institute, University of Miami, Miami, FL. |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.1097/cce.0000000000001323 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Detecting Pain Correlates With Recovery in Acute Brain Injury Patients With Disorders of Consciousness |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10645 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9998999834060669 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2711 |
| primary_topic.subfield.display_name | Emergency Medicine |
| primary_topic.display_name | Cardiac Arrest and Resuscitation |
| cited_by_count | 0 |
| locations_count | 4 |
| best_oa_location.id | doi:10.1097/cce.0000000000001323 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S4210210302 |
| best_oa_location.source.issn | 2639-8028 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2639-8028 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Critical Care Explorations |
| best_oa_location.source.host_organization | https://openalex.org/P4310318547 |
| best_oa_location.source.host_organization_name | Wolters Kluwer |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310318547 |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Critical Care Explorations |
| best_oa_location.landing_page_url | https://doi.org/10.1097/cce.0000000000001323 |
| primary_location.id | doi:10.1097/cce.0000000000001323 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S4210210302 |
| primary_location.source.issn | 2639-8028 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2639-8028 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Critical Care Explorations |
| primary_location.source.host_organization | https://openalex.org/P4310318547 |
| primary_location.source.host_organization_name | Wolters Kluwer |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310318547 |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Critical Care Explorations |
| primary_location.landing_page_url | https://doi.org/10.1097/cce.0000000000001323 |
| publication_date | 2025-09-24 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W4294308480, https://openalex.org/W2806663270, https://openalex.org/W3204792514, https://openalex.org/W3191838696, https://openalex.org/W2164201452, https://openalex.org/W3135183701, https://openalex.org/W2115998572, https://openalex.org/W2128770955, https://openalex.org/W2121804018, https://openalex.org/W3154955381, https://openalex.org/W2805518410, https://openalex.org/W4401562581, https://openalex.org/W4389627541, https://openalex.org/W4386046368, https://openalex.org/W2141464042, https://openalex.org/W2944434778, https://openalex.org/W2785641136, https://openalex.org/W2033349308, https://openalex.org/W2166537310, https://openalex.org/W2165740328, https://openalex.org/W3042854618, https://openalex.org/W2070921889, https://openalex.org/W2169918686, https://openalex.org/W2895368692, https://openalex.org/W4399116961, https://openalex.org/W4386169825, https://openalex.org/W1987293003, https://openalex.org/W2108029018, https://openalex.org/W2611753751, https://openalex.org/W2131165483, https://openalex.org/W4292836448, https://openalex.org/W2143417307, https://openalex.org/W2072227977, https://openalex.org/W3016259024, https://openalex.org/W2031397651, https://openalex.org/W4402816763, https://openalex.org/W3153215075, https://openalex.org/W2169118158, https://openalex.org/W2115742360, https://openalex.org/W1980075164, https://openalex.org/W2897356134, https://openalex.org/W1706861413, https://openalex.org/W2143635299, https://openalex.org/W4381929871 |
| referenced_works_count | 44 |
| abstract_inverted_index.( | 229, 238, 257 |
| abstract_inverted_index.3 | 104 |
| abstract_inverted_index.= | 231, 240, 259 |
| abstract_inverted_index.A | 121 |
| abstract_inverted_index.a | 18, 198, 288 |
| abstract_inverted_index.p | 233, 242, 261 |
| abstract_inverted_index.r | 230, 239, 258 |
| abstract_inverted_index.12 | 71, 192, 311 |
| abstract_inverted_index.17 | 161 |
| abstract_inverted_index.18 | 113 |
| abstract_inverted_index.27 | 124 |
| abstract_inverted_index.3) | 184 |
| abstract_inverted_index.3, | 68, 308 |
| abstract_inverted_index.36 | 152 |
| abstract_inverted_index.4) | 190 |
| abstract_inverted_index.45 | 99 |
| abstract_inverted_index.5% | 130 |
| abstract_inverted_index.50 | 111 |
| abstract_inverted_index.59 | 144 |
| abstract_inverted_index.6, | 69, 309 |
| abstract_inverted_index.62 | 93 |
| abstract_inverted_index.83 | 135 |
| abstract_inverted_index.Of | 90 |
| abstract_inverted_index.To | 1 |
| abstract_inverted_index.We | 169 |
| abstract_inverted_index.as | 4, 17, 285 |
| abstract_inverted_index.at | 67, 191, 216, 264, 307 |
| abstract_inverted_index.by | 6, 287 |
| abstract_inverted_index.in | 22, 194, 292, 313 |
| abstract_inverted_index.is | 297 |
| abstract_inverted_index.no | 273 |
| abstract_inverted_index.of | 30, 123, 131, 179, 201, 249 |
| abstract_inverted_index.on | 171 |
| abstract_inverted_index.or | 140, 148, 156, 165 |
| abstract_inverted_index.to | 83, 142, 150, 158, 167, 174, 254 |
| abstract_inverted_index.± | 112 |
| abstract_inverted_index.110 | 91 |
| abstract_inverted_index.5%, | 143 |
| abstract_inverted_index.69% | 119 |
| abstract_inverted_index.76% | 116 |
| abstract_inverted_index.ABI | 43, 314 |
| abstract_inverted_index.AND | 50 |
| abstract_inverted_index.ICU | 40, 294 |
| abstract_inverted_index.The | 203 |
| abstract_inverted_index.age | 109 |
| abstract_inverted_index.all | 269 |
| abstract_inverted_index.and | 14, 58, 70, 77, 88, 103, 118, 160, 185, 218, 245, 267, 280, 299, 304, 310 |
| abstract_inverted_index.for | 20, 211 |
| abstract_inverted_index.had | 95 |
| abstract_inverted_index.its | 15, 300 |
| abstract_inverted_index.the | 7, 246, 293 |
| abstract_inverted_index.two | 173 |
| abstract_inverted_index.was | 65, 110 |
| abstract_inverted_index.who | 196 |
| abstract_inverted_index.≥ | 183, 189 |
| abstract_inverted_index.< | 234, 243, 262 |
| abstract_inverted_index.(3%) | 105 |
| abstract_inverted_index.0.2; | 241 |
| abstract_inverted_index.10%, | 151 |
| abstract_inverted_index.15%, | 159 |
| abstract_inverted_index.20%. | 168 |
| abstract_inverted_index.CPOT | 59 |
| abstract_inverted_index.Coma | 214 |
| abstract_inverted_index.Data | 53 |
| abstract_inverted_index.DoC. | 46, 317 |
| abstract_inverted_index.MAIN | 51 |
| abstract_inverted_index.Pain | 284 |
| abstract_inverted_index.age, | 212 |
| abstract_inverted_index.care | 9 |
| abstract_inverted_index.even | 208 |
| abstract_inverted_index.less | 128 |
| abstract_inverted_index.odds | 178 |
| abstract_inverted_index.old, | 115 |
| abstract_inverted_index.pain | 3, 10, 87, 133, 274 |
| abstract_inverted_index.than | 129, 139, 147, 155, 164 |
| abstract_inverted_index.time | 270, 281 |
| abstract_inverted_index.tool | 12 |
| abstract_inverted_index.used | 290 |
| abstract_inverted_index.were | 81 |
| abstract_inverted_index.with | 28, 45, 205, 226, 316 |
| abstract_inverted_index.(16%) | 162 |
| abstract_inverted_index.(25%) | 126 |
| abstract_inverted_index.(33%) | 153 |
| abstract_inverted_index.(41%) | 100 |
| abstract_inverted_index.(54%) | 145 |
| abstract_inverted_index.(56%) | 94 |
| abstract_inverted_index.(75%) | 136 |
| abstract_inverted_index.(ABI) | 26 |
| abstract_inverted_index.(CPOT | 295 |
| abstract_inverted_index.(GOSE | 182, 188 |
| abstract_inverted_index.0.05) | 263 |
| abstract_inverted_index.0.23; | 232 |
| abstract_inverted_index.0.43; | 260 |
| abstract_inverted_index.GOSE, | 250 |
| abstract_inverted_index.GOSE. | 89 |
| abstract_inverted_index.None. | 48 |
| abstract_inverted_index.Scale | 215 |
| abstract_inverted_index.acute | 23 |
| abstract_inverted_index.after | 209 |
| abstract_inverted_index.brain | 24, 97 |
| abstract_inverted_index.equal | 141, 149, 157, 166 |
| abstract_inverted_index.found | 170 |
| abstract_inverted_index.pain. | 202 |
| abstract_inverted_index.score | 291 |
| abstract_inverted_index.three | 175 |
| abstract_inverted_index.times | 176 |
| abstract_inverted_index.total | 122 |
| abstract_inverted_index.years | 114 |
| abstract_inverted_index.(CPOT) | 13 |
| abstract_inverted_index.(DoC). | 32 |
| abstract_inverted_index.(GOSE) | 64 |
| abstract_inverted_index.0.05), | 235, 244 |
| abstract_inverted_index.White. | 120 |
| abstract_inverted_index.across | 268, 278 |
| abstract_inverted_index.assess | 84 |
| abstract_inverted_index.burden | 200, 222, 301 |
| abstract_inverted_index.common | 298 |
| abstract_inverted_index.higher | 177, 199 |
| abstract_inverted_index.injury | 25 |
| abstract_inverted_index.levels | 223, 275 |
| abstract_inverted_index.males, | 117 |
| abstract_inverted_index.models | 80 |
| abstract_inverted_index.months | 193, 312 |
| abstract_inverted_index.score) | 296 |
| abstract_inverted_index.study. | 37 |
| abstract_inverted_index.Average | 108 |
| abstract_inverted_index.DESIGN: | 33 |
| abstract_inverted_index.Glasgow | 61, 213 |
| abstract_inverted_index.Outcome | 62 |
| abstract_inverted_index.average | 172 |
| abstract_inverted_index.between | 86 |
| abstract_inverted_index.burden, | 134 |
| abstract_inverted_index.greater | 138, 146, 154, 163 |
| abstract_inverted_index.injury, | 98 |
| abstract_inverted_index.levels. | 220 |
| abstract_inverted_index.months. | 72 |
| abstract_inverted_index.points, | 271 |
| abstract_inverted_index.points. | 282 |
| abstract_inverted_index.scores. | 60 |
| abstract_inverted_index.sliding | 247 |
| abstract_inverted_index.whereas | 272 |
| abstract_inverted_index.12-month | 265 |
| abstract_inverted_index.RESULTS: | 52 |
| abstract_inverted_index.SETTING: | 38 |
| abstract_inverted_index.baseline | 255 |
| abstract_inverted_index.clinical | 56 |
| abstract_inverted_index.commonly | 289 |
| abstract_inverted_index.critical | 8 |
| abstract_inverted_index.evaluate | 2 |
| abstract_inverted_index.included | 54 |
| abstract_inverted_index.logistic | 78 |
| abstract_inverted_index.measured | 5 |
| abstract_inverted_index.obtained | 66 |
| abstract_inverted_index.outcomes | 206, 252, 279 |
| abstract_inverted_index.patients | 27, 44, 125, 195, 315 |
| abstract_inverted_index.recovery | 21, 181, 187, 228, 237, 306 |
| abstract_inverted_index.remained | 207 |
| abstract_inverted_index.sedation | 219 |
| abstract_inverted_index.severity | 256 |
| abstract_inverted_index.PATIENTS: | 42 |
| abstract_inverted_index.according | 253 |
| abstract_inverted_index.adjusting | 210 |
| abstract_inverted_index.biomarker | 19 |
| abstract_inverted_index.dichotomy | 248 |
| abstract_inverted_index.disorders | 29 |
| abstract_inverted_index.evaluated | 286 |
| abstract_inverted_index.follow-up | 266 |
| abstract_inverted_index.patients, | 92 |
| abstract_inverted_index.potential | 16 |
| abstract_inverted_index.tailoring | 251 |
| abstract_inverted_index.traumatic | 96 |
| abstract_inverted_index.admission, | 217 |
| abstract_inverted_index.calculated | 82 |
| abstract_inverted_index.correlated | 224, 276, 302 |
| abstract_inverted_index.experience | 197 |
| abstract_inverted_index.functional | 186, 236, 305 |
| abstract_inverted_index.negatively | 277 |
| abstract_inverted_index.positively | 225 |
| abstract_inverted_index.regression | 79 |
| abstract_inverted_index.Descriptive | 73 |
| abstract_inverted_index.OBJECTIVES: | 0 |
| abstract_inverted_index.Prospective | 34 |
| abstract_inverted_index.association | 204 |
| abstract_inverted_index.correlation | 75 |
| abstract_inverted_index.experienced | 127, 137 |
| abstract_inverted_index.hemorrhage, | 102 |
| abstract_inverted_index.hemorrhage. | 107 |
| abstract_inverted_index.observation | 11 |
| abstract_inverted_index.statistics, | 74 |
| abstract_inverted_index.2020–2024. | 41 |
| abstract_inverted_index.CONCLUSIONS: | 283 |
| abstract_inverted_index.MEASUREMENTS | 49 |
| abstract_inverted_index.Neuroscience | 39 |
| abstract_inverted_index.demographic, | 55 |
| abstract_inverted_index.subarachnoid | 106 |
| abstract_inverted_index.coefficients, | 76 |
| abstract_inverted_index.consciousness | 31, 180, 227, 303 |
| abstract_inverted_index.intracerebral | 101 |
| abstract_inverted_index.observational | 35 |
| abstract_inverted_index.relationships | 85 |
| abstract_inverted_index.single-center | 36 |
| abstract_inverted_index.INTERVENTIONS: | 47 |
| abstract_inverted_index.Scale-Extended | 63 |
| abstract_inverted_index.Moderate/severe | 221 |
| abstract_inverted_index.moderate/severe | 132 |
| abstract_inverted_index.characteristics, | 57 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 19 |
| citation_normalized_percentile.value | 0.59809382 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |