Development and validation of an echocardiographic algorithm to predict long-term mitral and tricuspid regurgitation progression Article Swipe
Jordan B. Strom
,
Yuansong Zhao
,
Changyu Shen
,
Jason H. Wasfy
,
Jiaman Xu
,
Evin Yucel
,
Varsha K. Tanguturi
,
Patrick M Hyland
,
Lawrence Markson
,
Dhruv S. Kazi
,
Jinghan Cui
,
Judy Hung
,
Robert W. Yeh
,
Warren J. Manning
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1093/ehjci/jeab254
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1093/ehjci/jeab254
Aims Prediction of mitral (MR) and tricuspid (TR) regurgitation progression on transthoracic echocardiography (TTE) is needed to personalize valvular surveillance intervals and prognostication. Methods and results Structured TTE report data at Beth Israel Deaconess Medical Center, 26 January 2000–31 December 2017, were used to determine time to progression (≥1+ increase in severity). TTE predictors of progression were used to create a progression score, externally validated at Massachusetts General Hospital, 1 January 2002–31 December 2019. In the derivation sample (MR, N = 34 933; TR, N = 27 526), only 5379 (15.4%) individuals with MR and 3630 (13.2%) with TR had progression during a median interquartile range) 9.0 (4.1–13.4) years of follow-up. Despite wide inter-individual variability in progression rates, a score based solely on demographics and TTE variables identified individuals with a five- to six-fold higher rate of MR/TR progression over 10 years (high- vs. low-score tertile, rate of progression; MR 20.1% vs. 3.3%; TR 21.2% vs. 4.4%). Compared to those in the lowest score tertile, those in the highest tertile of progression had a four-fold increased risk of mortality. On external validation, the score demonstrated similar performance to other algorithms commonly in use. Conclusion Four-fifths of individuals had no progression of MR or TR over two decades. Despite wide interindividual variability in progression rates, a score, based solely on TTE parameters, identified individuals with a five- to six-fold higher rate of MR/TR progression. Compared to the lowest tertile, individuals in the highest score tertile had a four-fold increased risk of mortality. Prediction of long-term MR/TR progression is not only feasible but prognostically important.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/ehjci/jeab254
- OA Status
- green
- Cited By
- 5
- References
- 29
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3217764233
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3217764233Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1093/ehjci/jeab254Digital Object Identifier
- Title
-
Development and validation of an echocardiographic algorithm to predict long-term mitral and tricuspid regurgitation progressionWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-11-12Full publication date if available
- Authors
-
Jordan B. Strom, Yuansong Zhao, Changyu Shen, Jason H. Wasfy, Jiaman Xu, Evin Yucel, Varsha K. Tanguturi, Patrick M Hyland, Lawrence Markson, Dhruv S. Kazi, Jinghan Cui, Judy Hung, Robert W. Yeh, Warren J. ManningList of authors in order
- Landing page
-
https://doi.org/10.1093/ehjci/jeab254Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://www.ncbi.nlm.nih.gov/pmc/articles/9989598Direct OA link when available
- Concepts
-
Term (time), Cardiology, Regurgitation (circulation), Internal medicine, Medicine, Mitral regurgitation, Algorithm, Computer science, Physics, Quantum mechanicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
5Total citation count in OpenAlex
- Citations by year (recent)
-
2024: 1, 2023: 3, 2022: 1Per-year citation counts (last 5 years)
- References (count)
-
29Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3217764233 |
|---|---|
| doi | https://doi.org/10.1093/ehjci/jeab254 |
| ids.doi | https://doi.org/10.1093/ehjci/jeab254 |
| ids.mag | 3217764233 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/34849685 |
| ids.openalex | https://openalex.org/W3217764233 |
| fwci | 0.88719659 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D006801 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Humans |
| mesh[1].qualifier_ui | Q000453 |
| mesh[1].descriptor_ui | D014262 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | epidemiology |
| mesh[1].descriptor_name | Tricuspid Valve Insufficiency |
| mesh[2].qualifier_ui | Q000453 |
| mesh[2].descriptor_ui | D008944 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | epidemiology |
| mesh[2].descriptor_name | Mitral Valve Insufficiency |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D012189 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Retrospective Studies |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D004452 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Echocardiography |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D000465 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Algorithms |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D016896 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Treatment Outcome |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D006801 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Humans |
| mesh[8].qualifier_ui | Q000453 |
| mesh[8].descriptor_ui | D014262 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | epidemiology |
| mesh[8].descriptor_name | Tricuspid Valve Insufficiency |
| mesh[9].qualifier_ui | Q000453 |
| mesh[9].descriptor_ui | D008944 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | epidemiology |
| mesh[9].descriptor_name | Mitral Valve Insufficiency |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D012189 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Retrospective Studies |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D004452 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Echocardiography |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D000465 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Algorithms |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D016896 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Treatment Outcome |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D006801 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Humans |
| mesh[15].qualifier_ui | Q000453 |
| mesh[15].descriptor_ui | D014262 |
| mesh[15].is_major_topic | True |
| mesh[15].qualifier_name | epidemiology |
| mesh[15].descriptor_name | Tricuspid Valve Insufficiency |
| mesh[16].qualifier_ui | Q000453 |
| mesh[16].descriptor_ui | D008944 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | epidemiology |
| mesh[16].descriptor_name | Mitral Valve Insufficiency |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D012189 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Retrospective Studies |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D004452 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Echocardiography |
| mesh[19].qualifier_ui | |
| mesh[19].descriptor_ui | D000465 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | |
| mesh[19].descriptor_name | Algorithms |
| mesh[20].qualifier_ui | |
| mesh[20].descriptor_ui | D016896 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | |
| mesh[20].descriptor_name | Treatment Outcome |
| type | article |
| title | Development and validation of an echocardiographic algorithm to predict long-term mitral and tricuspid regurgitation progression |
| awards[0].id | https://openalex.org/G6026429856 |
| awards[0].funder_id | https://openalex.org/F4320337338 |
| awards[0].display_name | |
| awards[0].funder_award_id | 1K23HL144907 |
| awards[0].funder_display_name | National Heart, Lung, and Blood Institute |
| biblio.issue | 12 |
| biblio.volume | 23 |
| biblio.last_page | 1616 |
| biblio.first_page | 1606 |
| topics[0].id | https://openalex.org/T10172 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2705 |
| topics[0].subfield.display_name | Cardiology and Cardiovascular Medicine |
| topics[0].display_name | Cardiac Valve Diseases and Treatments |
| topics[1].id | https://openalex.org/T10821 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9995999932289124 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2705 |
| topics[1].subfield.display_name | Cardiology and Cardiovascular Medicine |
| topics[1].display_name | Cardiovascular Function and Risk Factors |
| topics[2].id | https://openalex.org/T10372 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9973000288009644 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2741 |
| topics[2].subfield.display_name | Radiology, Nuclear Medicine and Imaging |
| topics[2].display_name | Cardiac Imaging and Diagnostics |
| funders[0].id | https://openalex.org/F4320332161 |
| funders[0].ror | https://ror.org/01cwqze88 |
| funders[0].display_name | National Institutes of Health |
| funders[1].id | https://openalex.org/F4320337338 |
| funders[1].ror | https://ror.org/012pb6c26 |
| funders[1].display_name | National Heart, Lung, and Blood Institute |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C61797465 |
| concepts[0].level | 2 |
| concepts[0].score | 0.6470268964767456 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q1188986 |
| concepts[0].display_name | Term (time) |
| concepts[1].id | https://openalex.org/C164705383 |
| concepts[1].level | 1 |
| concepts[1].score | 0.6008099317550659 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q10379 |
| concepts[1].display_name | Cardiology |
| concepts[2].id | https://openalex.org/C2780168065 |
| concepts[2].level | 2 |
| concepts[2].score | 0.6008014678955078 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q1930043 |
| concepts[2].display_name | Regurgitation (circulation) |
| concepts[3].id | https://openalex.org/C126322002 |
| concepts[3].level | 1 |
| concepts[3].score | 0.5476667881011963 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[3].display_name | Internal medicine |
| concepts[4].id | https://openalex.org/C71924100 |
| concepts[4].level | 0 |
| concepts[4].score | 0.49538886547088623 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[4].display_name | Medicine |
| concepts[5].id | https://openalex.org/C2993373945 |
| concepts[5].level | 2 |
| concepts[5].score | 0.4606160819530487 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q268292 |
| concepts[5].display_name | Mitral regurgitation |
| concepts[6].id | https://openalex.org/C11413529 |
| concepts[6].level | 1 |
| concepts[6].score | 0.41371864080429077 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q8366 |
| concepts[6].display_name | Algorithm |
| concepts[7].id | https://openalex.org/C41008148 |
| concepts[7].level | 0 |
| concepts[7].score | 0.22296273708343506 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q21198 |
| concepts[7].display_name | Computer science |
| concepts[8].id | https://openalex.org/C121332964 |
| concepts[8].level | 0 |
| concepts[8].score | 0.05250972509384155 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q413 |
| concepts[8].display_name | Physics |
| concepts[9].id | https://openalex.org/C62520636 |
| concepts[9].level | 1 |
| concepts[9].score | 0.0 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q944 |
| concepts[9].display_name | Quantum mechanics |
| keywords[0].id | https://openalex.org/keywords/term |
| keywords[0].score | 0.6470268964767456 |
| keywords[0].display_name | Term (time) |
| keywords[1].id | https://openalex.org/keywords/cardiology |
| keywords[1].score | 0.6008099317550659 |
| keywords[1].display_name | Cardiology |
| keywords[2].id | https://openalex.org/keywords/regurgitation |
| keywords[2].score | 0.6008014678955078 |
| keywords[2].display_name | Regurgitation (circulation) |
| keywords[3].id | https://openalex.org/keywords/internal-medicine |
| keywords[3].score | 0.5476667881011963 |
| keywords[3].display_name | Internal medicine |
| keywords[4].id | https://openalex.org/keywords/medicine |
| keywords[4].score | 0.49538886547088623 |
| keywords[4].display_name | Medicine |
| keywords[5].id | https://openalex.org/keywords/mitral-regurgitation |
| keywords[5].score | 0.4606160819530487 |
| keywords[5].display_name | Mitral regurgitation |
| keywords[6].id | https://openalex.org/keywords/algorithm |
| keywords[6].score | 0.41371864080429077 |
| keywords[6].display_name | Algorithm |
| keywords[7].id | https://openalex.org/keywords/computer-science |
| keywords[7].score | 0.22296273708343506 |
| keywords[7].display_name | Computer science |
| keywords[8].id | https://openalex.org/keywords/physics |
| keywords[8].score | 0.05250972509384155 |
| keywords[8].display_name | Physics |
| language | en |
| locations[0].id | doi:10.1093/ehjci/jeab254 |
| locations[0].is_oa | False |
| locations[0].source.id | https://openalex.org/S64942916 |
| locations[0].source.issn | 2047-2404, 2047-2412 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 2047-2404 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | European Heart Journal - Cardiovascular Imaging |
| locations[0].source.host_organization | https://openalex.org/P4310311648 |
| locations[0].source.host_organization_name | Oxford University Press |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310311648, https://openalex.org/P4310311647 |
| locations[0].source.host_organization_lineage_names | Oxford University Press, University of Oxford |
| locations[0].license | |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | European Heart Journal - Cardiovascular Imaging |
| locations[0].landing_page_url | https://doi.org/10.1093/ehjci/jeab254 |
| locations[1].id | pmid:34849685 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | European heart journal. Cardiovascular Imaging |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/34849685 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:9989598 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Eur Heart J Cardiovasc Imaging |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/9989598 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5002689169 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-6592-6141 |
| authorships[0].author.display_name | Jordan B. Strom |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I1316535847, https://openalex.org/I4210162526 |
| authorships[0].affiliations[0].raw_affiliation_string | Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I136199984 |
| authorships[0].affiliations[1].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[0].affiliations[2].institution_ids | https://openalex.org/I1316535847 |
| authorships[0].affiliations[2].raw_affiliation_string | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA |
| authorships[0].institutions[0].id | https://openalex.org/I1316535847 |
| authorships[0].institutions[0].ror | https://ror.org/04drvxt59 |
| authorships[0].institutions[0].type | healthcare |
| authorships[0].institutions[0].lineage | https://openalex.org/I1316535847 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | Beth Israel Deaconess Medical Center |
| authorships[0].institutions[1].id | https://openalex.org/I4210162526 |
| authorships[0].institutions[1].ror | https://ror.org/05vtzqy31 |
| authorships[0].institutions[1].type | healthcare |
| authorships[0].institutions[1].lineage | https://openalex.org/I4210162526 |
| authorships[0].institutions[1].country_code | US |
| authorships[0].institutions[1].display_name | Deaconess Hospital |
| authorships[0].institutions[2].id | https://openalex.org/I136199984 |
| authorships[0].institutions[2].ror | https://ror.org/03vek6s52 |
| authorships[0].institutions[2].type | education |
| authorships[0].institutions[2].lineage | https://openalex.org/I136199984 |
| authorships[0].institutions[2].country_code | US |
| authorships[0].institutions[2].display_name | Harvard University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Jordan B Strom |
| authorships[0].is_corresponding | True |
| authorships[0].raw_affiliation_strings | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA, Harvard Medical School , Boston, MA , USA, Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[1].author.id | https://openalex.org/A5011183619 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-5090-0985 |
| authorships[1].author.display_name | Yuansong Zhao |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I1316535847, https://openalex.org/I4210162526 |
| authorships[1].affiliations[0].raw_affiliation_string | Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[1].affiliations[1].institution_ids | https://openalex.org/I136199984 |
| authorships[1].affiliations[1].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[1].affiliations[2].institution_ids | https://openalex.org/I1316535847 |
| authorships[1].affiliations[2].raw_affiliation_string | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA |
| authorships[1].institutions[0].id | https://openalex.org/I1316535847 |
| authorships[1].institutions[0].ror | https://ror.org/04drvxt59 |
| authorships[1].institutions[0].type | healthcare |
| authorships[1].institutions[0].lineage | https://openalex.org/I1316535847 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | Beth Israel Deaconess Medical Center |
| authorships[1].institutions[1].id | https://openalex.org/I4210162526 |
| authorships[1].institutions[1].ror | https://ror.org/05vtzqy31 |
| authorships[1].institutions[1].type | healthcare |
| authorships[1].institutions[1].lineage | https://openalex.org/I4210162526 |
| authorships[1].institutions[1].country_code | US |
| authorships[1].institutions[1].display_name | Deaconess Hospital |
| authorships[1].institutions[2].id | https://openalex.org/I136199984 |
| authorships[1].institutions[2].ror | https://ror.org/03vek6s52 |
| authorships[1].institutions[2].type | education |
| authorships[1].institutions[2].lineage | https://openalex.org/I136199984 |
| authorships[1].institutions[2].country_code | US |
| authorships[1].institutions[2].display_name | Harvard University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Yuansong Zhao |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA, Harvard Medical School , Boston, MA , USA, Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[2].author.id | https://openalex.org/A5063081757 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-4444-0943 |
| authorships[2].author.display_name | Changyu Shen |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I1316535847, https://openalex.org/I4210162526 |
| authorships[2].affiliations[0].raw_affiliation_string | Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[2].affiliations[1].institution_ids | https://openalex.org/I136199984 |
| authorships[2].affiliations[1].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[2].affiliations[2].institution_ids | https://openalex.org/I1316535847 |
| authorships[2].affiliations[2].raw_affiliation_string | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA |
| authorships[2].institutions[0].id | https://openalex.org/I1316535847 |
| authorships[2].institutions[0].ror | https://ror.org/04drvxt59 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I1316535847 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | Beth Israel Deaconess Medical Center |
| authorships[2].institutions[1].id | https://openalex.org/I4210162526 |
| authorships[2].institutions[1].ror | https://ror.org/05vtzqy31 |
| authorships[2].institutions[1].type | healthcare |
| authorships[2].institutions[1].lineage | https://openalex.org/I4210162526 |
| authorships[2].institutions[1].country_code | US |
| authorships[2].institutions[1].display_name | Deaconess Hospital |
| authorships[2].institutions[2].id | https://openalex.org/I136199984 |
| authorships[2].institutions[2].ror | https://ror.org/03vek6s52 |
| authorships[2].institutions[2].type | education |
| authorships[2].institutions[2].lineage | https://openalex.org/I136199984 |
| authorships[2].institutions[2].country_code | US |
| authorships[2].institutions[2].display_name | Harvard University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Changyu Shen |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA, Harvard Medical School , Boston, MA , USA, Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[3].author.id | https://openalex.org/A5073645809 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-0871-5970 |
| authorships[3].author.display_name | Jason H. Wasfy |
| authorships[3].countries | US |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I136199984 |
| authorships[3].affiliations[0].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[3].affiliations[1].institution_ids | https://openalex.org/I4210087915 |
| authorships[3].affiliations[1].raw_affiliation_string | Division of Cardiology, Department of Medicine, Massachusetts General Hospital , Boston, MA , USA |
| authorships[3].institutions[0].id | https://openalex.org/I136199984 |
| authorships[3].institutions[0].ror | https://ror.org/03vek6s52 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I136199984 |
| authorships[3].institutions[0].country_code | US |
| authorships[3].institutions[0].display_name | Harvard University |
| authorships[3].institutions[1].id | https://openalex.org/I4210087915 |
| authorships[3].institutions[1].ror | https://ror.org/002pd6e78 |
| authorships[3].institutions[1].type | healthcare |
| authorships[3].institutions[1].lineage | https://openalex.org/I4210087915, https://openalex.org/I48633490 |
| authorships[3].institutions[1].country_code | US |
| authorships[3].institutions[1].display_name | Massachusetts General Hospital |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Jason H Wasfy |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Division of Cardiology, Department of Medicine, Massachusetts General Hospital , Boston, MA , USA, Harvard Medical School , Boston, MA , USA |
| authorships[4].author.id | https://openalex.org/A5109531873 |
| authorships[4].author.orcid | |
| authorships[4].author.display_name | Jiaman Xu |
| authorships[4].countries | US |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I1316535847, https://openalex.org/I4210162526 |
| authorships[4].affiliations[0].raw_affiliation_string | Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I136199984 |
| authorships[4].affiliations[1].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[4].affiliations[2].institution_ids | https://openalex.org/I1316535847 |
| authorships[4].affiliations[2].raw_affiliation_string | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA |
| authorships[4].institutions[0].id | https://openalex.org/I1316535847 |
| authorships[4].institutions[0].ror | https://ror.org/04drvxt59 |
| authorships[4].institutions[0].type | healthcare |
| authorships[4].institutions[0].lineage | https://openalex.org/I1316535847 |
| authorships[4].institutions[0].country_code | US |
| authorships[4].institutions[0].display_name | Beth Israel Deaconess Medical Center |
| authorships[4].institutions[1].id | https://openalex.org/I4210162526 |
| authorships[4].institutions[1].ror | https://ror.org/05vtzqy31 |
| authorships[4].institutions[1].type | healthcare |
| authorships[4].institutions[1].lineage | https://openalex.org/I4210162526 |
| authorships[4].institutions[1].country_code | US |
| authorships[4].institutions[1].display_name | Deaconess Hospital |
| authorships[4].institutions[2].id | https://openalex.org/I136199984 |
| authorships[4].institutions[2].ror | https://ror.org/03vek6s52 |
| authorships[4].institutions[2].type | education |
| authorships[4].institutions[2].lineage | https://openalex.org/I136199984 |
| authorships[4].institutions[2].country_code | US |
| authorships[4].institutions[2].display_name | Harvard University |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Jiaman Xu |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA, Harvard Medical School , Boston, MA , USA, Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[5].author.id | https://openalex.org/A5005057539 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-7074-6380 |
| authorships[5].author.display_name | Evin Yucel |
| authorships[5].countries | US |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I136199984 |
| authorships[5].affiliations[0].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[5].affiliations[1].institution_ids | https://openalex.org/I4210087915 |
| authorships[5].affiliations[1].raw_affiliation_string | Division of Cardiology, Department of Medicine, Massachusetts General Hospital , Boston, MA , USA |
| authorships[5].institutions[0].id | https://openalex.org/I136199984 |
| authorships[5].institutions[0].ror | https://ror.org/03vek6s52 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I136199984 |
| authorships[5].institutions[0].country_code | US |
| authorships[5].institutions[0].display_name | Harvard University |
| authorships[5].institutions[1].id | https://openalex.org/I4210087915 |
| authorships[5].institutions[1].ror | https://ror.org/002pd6e78 |
| authorships[5].institutions[1].type | healthcare |
| authorships[5].institutions[1].lineage | https://openalex.org/I4210087915, https://openalex.org/I48633490 |
| authorships[5].institutions[1].country_code | US |
| authorships[5].institutions[1].display_name | Massachusetts General Hospital |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Evin Yucel |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Division of Cardiology, Department of Medicine, Massachusetts General Hospital , Boston, MA , USA, Harvard Medical School , Boston, MA , USA |
| authorships[6].author.id | https://openalex.org/A5058791450 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-7437-182X |
| authorships[6].author.display_name | Varsha K. Tanguturi |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I136199984 |
| authorships[6].affiliations[0].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[6].affiliations[1].institution_ids | https://openalex.org/I4210087915 |
| authorships[6].affiliations[1].raw_affiliation_string | Division of Cardiology, Department of Medicine, Massachusetts General Hospital , Boston, MA , USA |
| authorships[6].institutions[0].id | https://openalex.org/I136199984 |
| authorships[6].institutions[0].ror | https://ror.org/03vek6s52 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I136199984 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | Harvard University |
| authorships[6].institutions[1].id | https://openalex.org/I4210087915 |
| authorships[6].institutions[1].ror | https://ror.org/002pd6e78 |
| authorships[6].institutions[1].type | healthcare |
| authorships[6].institutions[1].lineage | https://openalex.org/I4210087915, https://openalex.org/I48633490 |
| authorships[6].institutions[1].country_code | US |
| authorships[6].institutions[1].display_name | Massachusetts General Hospital |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Varsha Tanguturi |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Division of Cardiology, Department of Medicine, Massachusetts General Hospital , Boston, MA , USA, Harvard Medical School , Boston, MA , USA |
| authorships[7].author.id | https://openalex.org/A5065611604 |
| authorships[7].author.orcid | |
| authorships[7].author.display_name | Patrick M Hyland |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I136199984 |
| authorships[7].affiliations[0].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[7].affiliations[1].institution_ids | https://openalex.org/I1316535847 |
| authorships[7].affiliations[1].raw_affiliation_string | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA |
| authorships[7].institutions[0].id | https://openalex.org/I1316535847 |
| authorships[7].institutions[0].ror | https://ror.org/04drvxt59 |
| authorships[7].institutions[0].type | healthcare |
| authorships[7].institutions[0].lineage | https://openalex.org/I1316535847 |
| authorships[7].institutions[0].country_code | US |
| authorships[7].institutions[0].display_name | Beth Israel Deaconess Medical Center |
| authorships[7].institutions[1].id | https://openalex.org/I136199984 |
| authorships[7].institutions[1].ror | https://ror.org/03vek6s52 |
| authorships[7].institutions[1].type | education |
| authorships[7].institutions[1].lineage | https://openalex.org/I136199984 |
| authorships[7].institutions[1].country_code | US |
| authorships[7].institutions[1].display_name | Harvard University |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Patrick M Hyland |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA, Harvard Medical School , Boston, MA , USA |
| authorships[8].author.id | https://openalex.org/A5003174166 |
| authorships[8].author.orcid | https://orcid.org/0000-0001-7720-4683 |
| authorships[8].author.display_name | Lawrence Markson |
| authorships[8].countries | US |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I1316535847 |
| authorships[8].affiliations[0].raw_affiliation_string | Information Systems, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[8].affiliations[1].institution_ids | https://openalex.org/I136199984 |
| authorships[8].affiliations[1].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[8].institutions[0].id | https://openalex.org/I1316535847 |
| authorships[8].institutions[0].ror | https://ror.org/04drvxt59 |
| authorships[8].institutions[0].type | healthcare |
| authorships[8].institutions[0].lineage | https://openalex.org/I1316535847 |
| authorships[8].institutions[0].country_code | US |
| authorships[8].institutions[0].display_name | Beth Israel Deaconess Medical Center |
| authorships[8].institutions[1].id | https://openalex.org/I136199984 |
| authorships[8].institutions[1].ror | https://ror.org/03vek6s52 |
| authorships[8].institutions[1].type | education |
| authorships[8].institutions[1].lineage | https://openalex.org/I136199984 |
| authorships[8].institutions[1].country_code | US |
| authorships[8].institutions[1].display_name | Harvard University |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Lawrence J Markson |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Harvard Medical School , Boston, MA , USA, Information Systems, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[9].author.id | https://openalex.org/A5016472411 |
| authorships[9].author.orcid | https://orcid.org/0000-0002-9510-2979 |
| authorships[9].author.display_name | Dhruv S. Kazi |
| authorships[9].countries | US |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I1316535847, https://openalex.org/I4210162526 |
| authorships[9].affiliations[0].raw_affiliation_string | Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[9].affiliations[1].institution_ids | https://openalex.org/I136199984 |
| authorships[9].affiliations[1].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[9].affiliations[2].institution_ids | https://openalex.org/I1316535847 |
| authorships[9].affiliations[2].raw_affiliation_string | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA |
| authorships[9].institutions[0].id | https://openalex.org/I1316535847 |
| authorships[9].institutions[0].ror | https://ror.org/04drvxt59 |
| authorships[9].institutions[0].type | healthcare |
| authorships[9].institutions[0].lineage | https://openalex.org/I1316535847 |
| authorships[9].institutions[0].country_code | US |
| authorships[9].institutions[0].display_name | Beth Israel Deaconess Medical Center |
| authorships[9].institutions[1].id | https://openalex.org/I4210162526 |
| authorships[9].institutions[1].ror | https://ror.org/05vtzqy31 |
| authorships[9].institutions[1].type | healthcare |
| authorships[9].institutions[1].lineage | https://openalex.org/I4210162526 |
| authorships[9].institutions[1].country_code | US |
| authorships[9].institutions[1].display_name | Deaconess Hospital |
| authorships[9].institutions[2].id | https://openalex.org/I136199984 |
| authorships[9].institutions[2].ror | https://ror.org/03vek6s52 |
| authorships[9].institutions[2].type | education |
| authorships[9].institutions[2].lineage | https://openalex.org/I136199984 |
| authorships[9].institutions[2].country_code | US |
| authorships[9].institutions[2].display_name | Harvard University |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Dhruv S Kazi |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA, Harvard Medical School , Boston, MA , USA, Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[10].author.id | https://openalex.org/A5012438746 |
| authorships[10].author.orcid | https://orcid.org/0000-0001-6508-8849 |
| authorships[10].author.display_name | Jinghan Cui |
| authorships[10].countries | US |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I4210087915 |
| authorships[10].affiliations[0].raw_affiliation_string | Division of Cardiology, Department of Medicine, Massachusetts General Hospital , Boston, MA , USA |
| authorships[10].affiliations[1].institution_ids | https://openalex.org/I136199984 |
| authorships[10].affiliations[1].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[10].institutions[0].id | https://openalex.org/I136199984 |
| authorships[10].institutions[0].ror | https://ror.org/03vek6s52 |
| authorships[10].institutions[0].type | education |
| authorships[10].institutions[0].lineage | https://openalex.org/I136199984 |
| authorships[10].institutions[0].country_code | US |
| authorships[10].institutions[0].display_name | Harvard University |
| authorships[10].institutions[1].id | https://openalex.org/I4210087915 |
| authorships[10].institutions[1].ror | https://ror.org/002pd6e78 |
| authorships[10].institutions[1].type | healthcare |
| authorships[10].institutions[1].lineage | https://openalex.org/I4210087915, https://openalex.org/I48633490 |
| authorships[10].institutions[1].country_code | US |
| authorships[10].institutions[1].display_name | Massachusetts General Hospital |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Jinghan Cui |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Division of Cardiology, Department of Medicine, Massachusetts General Hospital , Boston, MA , USA, Harvard Medical School , Boston, MA , USA |
| authorships[11].author.id | https://openalex.org/A5082020218 |
| authorships[11].author.orcid | https://orcid.org/0000-0003-3737-7584 |
| authorships[11].author.display_name | Judy Hung |
| authorships[11].countries | US |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I136199984 |
| authorships[11].affiliations[0].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[11].affiliations[1].institution_ids | https://openalex.org/I4210087915 |
| authorships[11].affiliations[1].raw_affiliation_string | Division of Cardiology, Department of Medicine, Massachusetts General Hospital , Boston, MA , USA |
| authorships[11].institutions[0].id | https://openalex.org/I136199984 |
| authorships[11].institutions[0].ror | https://ror.org/03vek6s52 |
| authorships[11].institutions[0].type | education |
| authorships[11].institutions[0].lineage | https://openalex.org/I136199984 |
| authorships[11].institutions[0].country_code | US |
| authorships[11].institutions[0].display_name | Harvard University |
| authorships[11].institutions[1].id | https://openalex.org/I4210087915 |
| authorships[11].institutions[1].ror | https://ror.org/002pd6e78 |
| authorships[11].institutions[1].type | healthcare |
| authorships[11].institutions[1].lineage | https://openalex.org/I4210087915, https://openalex.org/I48633490 |
| authorships[11].institutions[1].country_code | US |
| authorships[11].institutions[1].display_name | Massachusetts General Hospital |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Judy Hung |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | Division of Cardiology, Department of Medicine, Massachusetts General Hospital , Boston, MA , USA, Harvard Medical School , Boston, MA , USA |
| authorships[12].author.id | https://openalex.org/A5089120659 |
| authorships[12].author.orcid | https://orcid.org/0000-0002-0564-4468 |
| authorships[12].author.display_name | Robert W. Yeh |
| authorships[12].countries | US |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I1316535847, https://openalex.org/I4210162526 |
| authorships[12].affiliations[0].raw_affiliation_string | Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[12].affiliations[1].institution_ids | https://openalex.org/I136199984 |
| authorships[12].affiliations[1].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[12].affiliations[2].institution_ids | https://openalex.org/I1316535847 |
| authorships[12].affiliations[2].raw_affiliation_string | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA |
| authorships[12].institutions[0].id | https://openalex.org/I1316535847 |
| authorships[12].institutions[0].ror | https://ror.org/04drvxt59 |
| authorships[12].institutions[0].type | healthcare |
| authorships[12].institutions[0].lineage | https://openalex.org/I1316535847 |
| authorships[12].institutions[0].country_code | US |
| authorships[12].institutions[0].display_name | Beth Israel Deaconess Medical Center |
| authorships[12].institutions[1].id | https://openalex.org/I4210162526 |
| authorships[12].institutions[1].ror | https://ror.org/05vtzqy31 |
| authorships[12].institutions[1].type | healthcare |
| authorships[12].institutions[1].lineage | https://openalex.org/I4210162526 |
| authorships[12].institutions[1].country_code | US |
| authorships[12].institutions[1].display_name | Deaconess Hospital |
| authorships[12].institutions[2].id | https://openalex.org/I136199984 |
| authorships[12].institutions[2].ror | https://ror.org/03vek6s52 |
| authorships[12].institutions[2].type | education |
| authorships[12].institutions[2].lineage | https://openalex.org/I136199984 |
| authorships[12].institutions[2].country_code | US |
| authorships[12].institutions[2].display_name | Harvard University |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Robert W Yeh |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA, Harvard Medical School , Boston, MA , USA, Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[13].author.id | https://openalex.org/A5002927848 |
| authorships[13].author.orcid | https://orcid.org/0000-0001-7199-2543 |
| authorships[13].author.display_name | Warren J. Manning |
| authorships[13].countries | US |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I1316535847 |
| authorships[13].affiliations[0].raw_affiliation_string | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA |
| authorships[13].affiliations[1].institution_ids | https://openalex.org/I136199984 |
| authorships[13].affiliations[1].raw_affiliation_string | Harvard Medical School , Boston, MA , USA |
| authorships[13].affiliations[2].institution_ids | https://openalex.org/I1316535847 |
| authorships[13].affiliations[2].raw_affiliation_string | Department of Radiology, Beth Israel Deaconess Medical Center , Boston, MA , USA |
| authorships[13].institutions[0].id | https://openalex.org/I1316535847 |
| authorships[13].institutions[0].ror | https://ror.org/04drvxt59 |
| authorships[13].institutions[0].type | healthcare |
| authorships[13].institutions[0].lineage | https://openalex.org/I1316535847 |
| authorships[13].institutions[0].country_code | US |
| authorships[13].institutions[0].display_name | Beth Israel Deaconess Medical Center |
| authorships[13].institutions[1].id | https://openalex.org/I136199984 |
| authorships[13].institutions[1].ror | https://ror.org/03vek6s52 |
| authorships[13].institutions[1].type | education |
| authorships[13].institutions[1].lineage | https://openalex.org/I136199984 |
| authorships[13].institutions[1].country_code | US |
| authorships[13].institutions[1].display_name | Harvard University |
| authorships[13].author_position | last |
| authorships[13].raw_author_name | Warren J Manning |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center , 375 Longwood Avenue, 4th floor, Boston, MA 02215 , USA, Department of Radiology, Beth Israel Deaconess Medical Center , Boston, MA , USA, Harvard Medical School , Boston, MA , USA |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.ncbi.nlm.nih.gov/pmc/articles/9989598 |
| open_access.oa_status | green |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Development and validation of an echocardiographic algorithm to predict long-term mitral and tricuspid regurgitation progression |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10172 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2705 |
| primary_topic.subfield.display_name | Cardiology and Cardiovascular Medicine |
| primary_topic.display_name | Cardiac Valve Diseases and Treatments |
| related_works | https://openalex.org/W4387497383, https://openalex.org/W3183948672, https://openalex.org/W3173606202, https://openalex.org/W3110381201, https://openalex.org/W2948807893, https://openalex.org/W2899084033, https://openalex.org/W2778153218, https://openalex.org/W2758277628, https://openalex.org/W1531601525, https://openalex.org/W2146027663 |
| cited_by_count | 5 |
| counts_by_year[0].year | 2024 |
| counts_by_year[0].cited_by_count | 1 |
| counts_by_year[1].year | 2023 |
| counts_by_year[1].cited_by_count | 3 |
| counts_by_year[2].year | 2022 |
| counts_by_year[2].cited_by_count | 1 |
| locations_count | 3 |
| best_oa_location.id | pmh:oai:pubmedcentral.nih.gov:9989598 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2764455111 |
| best_oa_location.source.issn | |
| best_oa_location.source.type | repository |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | |
| best_oa_location.source.is_core | False |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | PubMed Central |
| best_oa_location.source.host_organization | https://openalex.org/I1299303238 |
| best_oa_location.source.host_organization_name | National Institutes of Health |
| best_oa_location.source.host_organization_lineage | https://openalex.org/I1299303238 |
| best_oa_location.license | |
| best_oa_location.pdf_url | |
| best_oa_location.version | submittedVersion |
| best_oa_location.raw_type | Text |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | False |
| best_oa_location.is_published | False |
| best_oa_location.raw_source_name | Eur Heart J Cardiovasc Imaging |
| best_oa_location.landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/9989598 |
| primary_location.id | doi:10.1093/ehjci/jeab254 |
| primary_location.is_oa | False |
| primary_location.source.id | https://openalex.org/S64942916 |
| primary_location.source.issn | 2047-2404, 2047-2412 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 2047-2404 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | European Heart Journal - Cardiovascular Imaging |
| primary_location.source.host_organization | https://openalex.org/P4310311648 |
| primary_location.source.host_organization_name | Oxford University Press |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310311648, https://openalex.org/P4310311647 |
| primary_location.source.host_organization_lineage_names | Oxford University Press, University of Oxford |
| primary_location.license | |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | European Heart Journal - Cardiovascular Imaging |
| primary_location.landing_page_url | https://doi.org/10.1093/ehjci/jeab254 |
| publication_date | 2021-11-12 |
| publication_year | 2021 |
| referenced_works | https://openalex.org/W2122694177, https://openalex.org/W2142960358, https://openalex.org/W1974432041, https://openalex.org/W3193598686, https://openalex.org/W3195842247, https://openalex.org/W56803693, https://openalex.org/W2309990757, https://openalex.org/W2790914134, https://openalex.org/W2262637319, https://openalex.org/W2883167334, https://openalex.org/W3092239629, https://openalex.org/W2062411234, https://openalex.org/W2596797126, https://openalex.org/W2147700244, https://openalex.org/W2037964948, https://openalex.org/W2112050863, https://openalex.org/W2750101675, https://openalex.org/W2914820223, https://openalex.org/W2057355395, https://openalex.org/W2312383916, https://openalex.org/W2012294231, https://openalex.org/W2134621187, https://openalex.org/W2324839838, https://openalex.org/W2062786076, https://openalex.org/W1994323476, https://openalex.org/W2745029045, https://openalex.org/W1975495017, https://openalex.org/W2133465367, https://openalex.org/W2975529962 |
| referenced_works_count | 29 |
| abstract_inverted_index.1 | 70 |
| abstract_inverted_index.= | 81, 86 |
| abstract_inverted_index.N | 80, 85 |
| abstract_inverted_index.a | 61, 103, 119, 131, 174, 215, 225, 246 |
| abstract_inverted_index.10 | 141 |
| abstract_inverted_index.26 | 37 |
| abstract_inverted_index.27 | 87 |
| abstract_inverted_index.34 | 82 |
| abstract_inverted_index.In | 75 |
| abstract_inverted_index.MR | 94, 150, 202 |
| abstract_inverted_index.On | 180 |
| abstract_inverted_index.TR | 99, 154, 204 |
| abstract_inverted_index.at | 31, 66 |
| abstract_inverted_index.in | 51, 116, 161, 167, 192, 212, 240 |
| abstract_inverted_index.is | 15, 257 |
| abstract_inverted_index.no | 199 |
| abstract_inverted_index.of | 3, 55, 110, 137, 148, 171, 178, 196, 201, 231, 250, 253 |
| abstract_inverted_index.on | 11, 123, 219 |
| abstract_inverted_index.or | 203 |
| abstract_inverted_index.to | 17, 44, 47, 59, 133, 159, 188, 227, 235 |
| abstract_inverted_index.9.0 | 107 |
| abstract_inverted_index.TR, | 84 |
| abstract_inverted_index.TTE | 28, 53, 126, 220 |
| abstract_inverted_index.and | 6, 22, 25, 95, 125 |
| abstract_inverted_index.but | 261 |
| abstract_inverted_index.had | 100, 173, 198, 245 |
| abstract_inverted_index.not | 258 |
| abstract_inverted_index.the | 76, 162, 168, 183, 236, 241 |
| abstract_inverted_index.two | 206 |
| abstract_inverted_index.vs. | 144, 152, 156 |
| abstract_inverted_index.(MR) | 5 |
| abstract_inverted_index.(MR, | 79 |
| abstract_inverted_index.(TR) | 8 |
| abstract_inverted_index.3630 | 96 |
| abstract_inverted_index.5379 | 90 |
| abstract_inverted_index.933; | 83 |
| abstract_inverted_index.Aims | 1 |
| abstract_inverted_index.Beth | 32 |
| abstract_inverted_index.data | 30 |
| abstract_inverted_index.only | 89, 259 |
| abstract_inverted_index.over | 140, 205 |
| abstract_inverted_index.rate | 136, 147, 230 |
| abstract_inverted_index.risk | 177, 249 |
| abstract_inverted_index.time | 46 |
| abstract_inverted_index.use. | 193 |
| abstract_inverted_index.used | 43, 58 |
| abstract_inverted_index.were | 42, 57 |
| abstract_inverted_index.wide | 113, 209 |
| abstract_inverted_index.with | 93, 98, 130, 224 |
| abstract_inverted_index.(TTE) | 14 |
| abstract_inverted_index.20.1% | 151 |
| abstract_inverted_index.2017, | 41 |
| abstract_inverted_index.2019. | 74 |
| abstract_inverted_index.21.2% | 155 |
| abstract_inverted_index.3.3%; | 153 |
| abstract_inverted_index.526), | 88 |
| abstract_inverted_index.MR/TR | 138, 232, 255 |
| abstract_inverted_index.based | 121, 217 |
| abstract_inverted_index.five- | 132, 226 |
| abstract_inverted_index.other | 189 |
| abstract_inverted_index.score | 120, 164, 184, 243 |
| abstract_inverted_index.those | 160, 166 |
| abstract_inverted_index.years | 109, 142 |
| abstract_inverted_index.(high- | 143 |
| abstract_inverted_index.(≥1+ | 49 |
| abstract_inverted_index.4.4%). | 157 |
| abstract_inverted_index.Israel | 33 |
| abstract_inverted_index.create | 60 |
| abstract_inverted_index.during | 102 |
| abstract_inverted_index.higher | 135, 229 |
| abstract_inverted_index.lowest | 163, 237 |
| abstract_inverted_index.median | 104 |
| abstract_inverted_index.mitral | 4 |
| abstract_inverted_index.needed | 16 |
| abstract_inverted_index.range) | 106 |
| abstract_inverted_index.rates, | 118, 214 |
| abstract_inverted_index.report | 29 |
| abstract_inverted_index.sample | 78 |
| abstract_inverted_index.score, | 63, 216 |
| abstract_inverted_index.solely | 122, 218 |
| abstract_inverted_index.(13.2%) | 97 |
| abstract_inverted_index.(15.4%) | 91 |
| abstract_inverted_index.Center, | 36 |
| abstract_inverted_index.Despite | 112, 208 |
| abstract_inverted_index.General | 68 |
| abstract_inverted_index.January | 38, 71 |
| abstract_inverted_index.Medical | 35 |
| abstract_inverted_index.Methods | 24 |
| abstract_inverted_index.highest | 169, 242 |
| abstract_inverted_index.results | 26 |
| abstract_inverted_index.similar | 186 |
| abstract_inverted_index.tertile | 170, 244 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Compared | 158, 234 |
| abstract_inverted_index.December | 40, 73 |
| abstract_inverted_index.commonly | 191 |
| abstract_inverted_index.decades. | 207 |
| abstract_inverted_index.external | 181 |
| abstract_inverted_index.feasible | 260 |
| abstract_inverted_index.increase | 50 |
| abstract_inverted_index.six-fold | 134, 228 |
| abstract_inverted_index.tertile, | 146, 165, 238 |
| abstract_inverted_index.valvular | 19 |
| abstract_inverted_index.2000–31 | 39 |
| abstract_inverted_index.2002–31 | 72 |
| abstract_inverted_index.Deaconess | 34 |
| abstract_inverted_index.Hospital, | 69 |
| abstract_inverted_index.determine | 45 |
| abstract_inverted_index.four-fold | 175, 247 |
| abstract_inverted_index.increased | 176, 248 |
| abstract_inverted_index.intervals | 21 |
| abstract_inverted_index.long-term | 254 |
| abstract_inverted_index.low-score | 145 |
| abstract_inverted_index.tricuspid | 7 |
| abstract_inverted_index.validated | 65 |
| abstract_inverted_index.variables | 127 |
| abstract_inverted_index.Conclusion | 194 |
| abstract_inverted_index.Prediction | 2, 252 |
| abstract_inverted_index.Structured | 27 |
| abstract_inverted_index.algorithms | 190 |
| abstract_inverted_index.derivation | 77 |
| abstract_inverted_index.externally | 64 |
| abstract_inverted_index.follow-up. | 111 |
| abstract_inverted_index.identified | 128, 222 |
| abstract_inverted_index.important. | 263 |
| abstract_inverted_index.mortality. | 179, 251 |
| abstract_inverted_index.predictors | 54 |
| abstract_inverted_index.severity). | 52 |
| abstract_inverted_index.Four-fifths | 195 |
| abstract_inverted_index.individuals | 92, 129, 197, 223, 239 |
| abstract_inverted_index.parameters, | 221 |
| abstract_inverted_index.performance | 187 |
| abstract_inverted_index.personalize | 18 |
| abstract_inverted_index.progression | 10, 48, 56, 62, 101, 117, 139, 172, 200, 213, 256 |
| abstract_inverted_index.validation, | 182 |
| abstract_inverted_index.variability | 115, 211 |
| abstract_inverted_index.(4.1–13.4) | 108 |
| abstract_inverted_index.demographics | 124 |
| abstract_inverted_index.demonstrated | 185 |
| abstract_inverted_index.progression. | 233 |
| abstract_inverted_index.progression; | 149 |
| abstract_inverted_index.surveillance | 20 |
| abstract_inverted_index.Massachusetts | 67 |
| abstract_inverted_index.interquartile | 105 |
| abstract_inverted_index.regurgitation | 9 |
| abstract_inverted_index.transthoracic | 12 |
| abstract_inverted_index.prognostically | 262 |
| abstract_inverted_index.interindividual | 210 |
| abstract_inverted_index.echocardiography | 13 |
| abstract_inverted_index.inter-individual | 114 |
| abstract_inverted_index.prognostication. | 23 |
| cited_by_percentile_year.max | 97 |
| cited_by_percentile_year.min | 89 |
| corresponding_author_ids | https://openalex.org/A5002689169 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 14 |
| corresponding_institution_ids | https://openalex.org/I1316535847, https://openalex.org/I136199984, https://openalex.org/I4210162526 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.8700000047683716 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.75134017 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |