Development of a Fluorescence in Situ Hybridization Probe for Detecting IKZF1 Deletion Mutations in Patients with Acute Lymphoblastic Leukemia Article Swipe

PDF

Junichi Hashiguchi , Masahiro Onozawa , Satoshi Oguri , Shinichi Fujisawa , Masahisa Tsuji , Kohei Okada , Masao Nakagawa , Daigo Hashimoto , Kaoru Kahata , Takeshi Kondo , Chikara Shimizu , Takanori Teshima ·

YOU? · · 2018 · Open Access · · DOI: https://doi.org/10.1016/j.jmoldx.2018.02.005

Related Topics

Fluorescence In Situ Hybridization

Biology

Molecular Biology

Tom Clancy's Ghost Recon Breakpoint

Chromosomal Translocation

Concepts

Fluorescence in situ hybridization Biology Recombination signal sequences Molecular biology Breakpoint Gene rearrangement Genetics Exon clone (Java method) Chromosomal translocation Recombination-activating gene Chromosome Recombination Gene

Metadata

Type: article
Language: en
Landing Page: https://doi.org/10.1016/j.jmoldx.2018.02.005
PDF: http://jmd.amjpathol.org/article/S1525157817304129/pdf
OA Status: bronze
Cited By: 5
References: 27
Related Works: 10
OpenAlex ID: https://openalex.org/W2810463412

All OpenAlex metadata

Raw OpenAlex JSON

OpenAlex ID: https://openalex.org/W2810463412

Canonical identifier for this work in OpenAlex
DOI: https://doi.org/10.1016/j.jmoldx.2018.02.005

Digital Object Identifier
Title: Development of a Fluorescence in Situ Hybridization Probe for Detecting IKZF1 Deletion Mutations in Patients with Acute Lymphoblastic Leukemia

Work title
Type: article

OpenAlex work type
Language: en

Primary language
Publication year: 2018

Year of publication
Publication date: 2018-06-25

Full publication date if available
Authors: Junichi Hashiguchi, Masahiro Onozawa, Satoshi Oguri, Shinichi Fujisawa, Masahisa Tsuji, Kohei Okada, Masao Nakagawa, Daigo Hashimoto, Kaoru Kahata, Takeshi Kondo, Chikara Shimizu, Takanori Teshima

List of authors in order
Landing page: https://doi.org/10.1016/j.jmoldx.2018.02.005

Publisher landing page
PDF URL: https://jmd.amjpathol.org/article/S1525157817304129/pdf

Direct link to full text PDF
Open access: Yes

Whether a free full text is available
OA status: bronze

Open access status per OpenAlex
OA URL: https://jmd.amjpathol.org/article/S1525157817304129/pdf

Direct OA link when available
Concepts: Fluorescence in situ hybridization, Biology, Recombination signal sequences, Molecular biology, Breakpoint, Gene rearrangement, Genetics, Exon, clone (Java method), Chromosomal translocation, Recombination-activating gene, Chromosome, Recombination, Gene

Top concepts (fields/topics) attached by OpenAlex
Cited by: 5

Total citation count in OpenAlex
Citations by year (recent): 2024: 1, 2023: 2, 2020: 1, 2018: 1

Per-year citation counts (last 5 years)
References (count): 27

Number of works referenced by this work
Related works (count): 10

Other works algorithmically related by OpenAlex

Full payload

id	https://openalex.org/W2810463412
doi	https://doi.org/10.1016/j.jmoldx.2018.02.005
ids.doi	https://doi.org/10.1016/j.jmoldx.2018.02.005
ids.mag	2810463412
ids.pmid	https://pubmed.ncbi.nlm.nih.gov/29957452
ids.openalex	https://openalex.org/W2810463412
fwci	0.54791024
mesh[0].qualifier_ui
mesh[0].descriptor_ui	D000328
mesh[0].is_major_topic	False
mesh[0].qualifier_name
mesh[0].descriptor_name	Adult
mesh[1].qualifier_ui
mesh[1].descriptor_ui	D000368
mesh[1].is_major_topic	False
mesh[1].qualifier_name
mesh[1].descriptor_name	Aged
mesh[2].qualifier_ui
mesh[2].descriptor_ui	D000369
mesh[2].is_major_topic	False
mesh[2].qualifier_name
mesh[2].descriptor_name	Aged, 80 and over
mesh[3].qualifier_ui
mesh[3].descriptor_ui	D001483
mesh[3].is_major_topic	False
mesh[3].qualifier_name
mesh[3].descriptor_name	Base Sequence
mesh[4].qualifier_ui
mesh[4].descriptor_ui	D045744
mesh[4].is_major_topic	False
mesh[4].qualifier_name
mesh[4].descriptor_name	Cell Line, Tumor
mesh[5].qualifier_ui
mesh[5].descriptor_ui	D002648
mesh[5].is_major_topic	False
mesh[5].qualifier_name
mesh[5].descriptor_name	Child
mesh[6].qualifier_ui
mesh[6].descriptor_ui	D005260
mesh[6].is_major_topic	False
mesh[6].qualifier_name
mesh[6].descriptor_name	Female
mesh[7].qualifier_ui
mesh[7].descriptor_ui	D006801
mesh[7].is_major_topic	False
mesh[7].qualifier_name
mesh[7].descriptor_name	Humans
mesh[8].qualifier_ui	Q000235
mesh[8].descriptor_ui	D051740
mesh[8].is_major_topic	False
mesh[8].qualifier_name	genetics
mesh[8].descriptor_name	Ikaros Transcription Factor
mesh[9].qualifier_ui	Q000379
mesh[9].descriptor_ui	D017404
mesh[9].is_major_topic	False
mesh[9].qualifier_name	methods
mesh[9].descriptor_name	In Situ Hybridization, Fluorescence
mesh[10].qualifier_ui
mesh[10].descriptor_ui	D007399
mesh[10].is_major_topic	False
mesh[10].qualifier_name
mesh[10].descriptor_name	Interphase
mesh[11].qualifier_ui
mesh[11].descriptor_ui	D008297
mesh[11].is_major_topic	False
mesh[11].qualifier_name
mesh[11].descriptor_name	Male
mesh[12].qualifier_ui
mesh[12].descriptor_ui	D008875
mesh[12].is_major_topic	False
mesh[12].qualifier_name
mesh[12].descriptor_name	Middle Aged
mesh[13].qualifier_ui	Q000235
mesh[13].descriptor_ui	D054198
mesh[13].is_major_topic	False
mesh[13].qualifier_name	genetics
mesh[13].descriptor_name	Precursor Cell Lymphoblastic Leukemia-Lymphoma
mesh[14].qualifier_ui	Q000378
mesh[14].descriptor_ui	D015347
mesh[14].is_major_topic	False
mesh[14].qualifier_name	metabolism
mesh[14].descriptor_name	RNA Probes
mesh[15].qualifier_ui	Q000235
mesh[15].descriptor_ui	D017384
mesh[15].is_major_topic	False
mesh[15].qualifier_name	genetics
mesh[15].descriptor_name	Sequence Deletion
mesh[16].qualifier_ui
mesh[16].descriptor_ui	D055815
mesh[16].is_major_topic	False
mesh[16].qualifier_name
mesh[16].descriptor_name	Young Adult
mesh[17].qualifier_ui
mesh[17].descriptor_ui	D000328
mesh[17].is_major_topic	False
mesh[17].qualifier_name
mesh[17].descriptor_name	Adult
mesh[18].qualifier_ui
mesh[18].descriptor_ui	D000368
mesh[18].is_major_topic	False
mesh[18].qualifier_name
mesh[18].descriptor_name	Aged
mesh[19].qualifier_ui
mesh[19].descriptor_ui	D000369
mesh[19].is_major_topic	False
mesh[19].qualifier_name
mesh[19].descriptor_name	Aged, 80 and over
mesh[20].qualifier_ui
mesh[20].descriptor_ui	D001483
mesh[20].is_major_topic	False
mesh[20].qualifier_name
mesh[20].descriptor_name	Base Sequence
mesh[21].qualifier_ui
mesh[21].descriptor_ui	D045744
mesh[21].is_major_topic	False
mesh[21].qualifier_name
mesh[21].descriptor_name	Cell Line, Tumor
mesh[22].qualifier_ui
mesh[22].descriptor_ui	D002648
mesh[22].is_major_topic	False
mesh[22].qualifier_name
mesh[22].descriptor_name	Child
mesh[23].qualifier_ui
mesh[23].descriptor_ui	D005260
mesh[23].is_major_topic	False
mesh[23].qualifier_name
mesh[23].descriptor_name	Female
mesh[24].qualifier_ui
mesh[24].descriptor_ui	D006801
mesh[24].is_major_topic	False
mesh[24].qualifier_name
mesh[24].descriptor_name	Humans
mesh[25].qualifier_ui	Q000235
mesh[25].descriptor_ui	D051740
mesh[25].is_major_topic	False
mesh[25].qualifier_name	genetics
mesh[25].descriptor_name	Ikaros Transcription Factor
mesh[26].qualifier_ui	Q000379
mesh[26].descriptor_ui	D017404
mesh[26].is_major_topic	False
mesh[26].qualifier_name	methods
mesh[26].descriptor_name	In Situ Hybridization, Fluorescence
mesh[27].qualifier_ui
mesh[27].descriptor_ui	D007399
mesh[27].is_major_topic	False
mesh[27].qualifier_name
mesh[27].descriptor_name	Interphase
mesh[28].qualifier_ui
mesh[28].descriptor_ui	D008297
mesh[28].is_major_topic	False
mesh[28].qualifier_name
mesh[28].descriptor_name	Male
mesh[29].qualifier_ui
mesh[29].descriptor_ui	D008875
mesh[29].is_major_topic	False
mesh[29].qualifier_name
mesh[29].descriptor_name	Middle Aged
mesh[30].qualifier_ui	Q000235
mesh[30].descriptor_ui	D054198
mesh[30].is_major_topic	False
mesh[30].qualifier_name	genetics
mesh[30].descriptor_name	Precursor Cell Lymphoblastic Leukemia-Lymphoma
mesh[31].qualifier_ui	Q000378
mesh[31].descriptor_ui	D015347
mesh[31].is_major_topic	False
mesh[31].qualifier_name	metabolism
mesh[31].descriptor_name	RNA Probes
mesh[32].qualifier_ui	Q000235
mesh[32].descriptor_ui	D017384
mesh[32].is_major_topic	False
mesh[32].qualifier_name	genetics
mesh[32].descriptor_name	Sequence Deletion
mesh[33].qualifier_ui
mesh[33].descriptor_ui	D055815
mesh[33].is_major_topic	False
mesh[33].qualifier_name
mesh[33].descriptor_name	Young Adult
type	article
title	Development of a Fluorescence in Situ Hybridization Probe for Detecting IKZF1 Deletion Mutations in Patients with Acute Lymphoblastic Leukemia
biblio.issue	4
biblio.volume	20
biblio.last_page	454
biblio.first_page	446
grants[0].funder	https://openalex.org/F4320334764
grants[0].award_id	17K16174
grants[0].funder_display_name	Japan Society for the Promotion of Science
topics[0].id	https://openalex.org/T10950
topics[0].field.id	https://openalex.org/fields/27
topics[0].field.display_name	Medicine
topics[0].score	1.0
topics[0].domain.id	https://openalex.org/domains/4
topics[0].domain.display_name	Health Sciences
topics[0].subfield.id	https://openalex.org/subfields/2739
topics[0].subfield.display_name	Public Health, Environmental and Occupational Health
topics[0].display_name	Acute Lymphoblastic Leukemia research
topics[1].id	https://openalex.org/T10123
topics[1].field.id	https://openalex.org/fields/13
topics[1].field.display_name	Biochemistry, Genetics and Molecular Biology
topics[1].score	0.9865999817848206
topics[1].domain.id	https://openalex.org/domains/1
topics[1].domain.display_name	Life Sciences
topics[1].subfield.id	https://openalex.org/subfields/1312
topics[1].subfield.display_name	Molecular Biology
topics[1].display_name	DNA Repair Mechanisms
topics[2].id	https://openalex.org/T10309
topics[2].field.id	https://openalex.org/fields/27
topics[2].field.display_name	Medicine
topics[2].score	0.984499990940094
topics[2].domain.id	https://openalex.org/domains/4
topics[2].domain.display_name	Health Sciences
topics[2].subfield.id	https://openalex.org/subfields/2720
topics[2].subfield.display_name	Hematology
topics[2].display_name	Acute Myeloid Leukemia Research
funders[0].id	https://openalex.org/F4320334764
funders[0].ror	https://ror.org/00hhkn466
funders[0].display_name	Japan Society for the Promotion of Science
is_xpac	False
apc_list.value	3000
apc_list.currency	USD
apc_list.value_usd	3000
apc_paid
concepts[0].id	https://openalex.org/C2777542201
concepts[0].level	4
concepts[0].score	0.7731142044067383
concepts[0].wikidata	https://www.wikidata.org/wiki/Q1336182
concepts[0].display_name	Fluorescence in situ hybridization
concepts[1].id	https://openalex.org/C86803240
concepts[1].level	0
concepts[1].score	0.7162935733795166
concepts[1].wikidata	https://www.wikidata.org/wiki/Q420
concepts[1].display_name	Biology
concepts[2].id	https://openalex.org/C157402786
concepts[2].level	5
concepts[2].score	0.7067198753356934
concepts[2].wikidata	https://www.wikidata.org/wiki/Q7302710
concepts[2].display_name	Recombination signal sequences
concepts[3].id	https://openalex.org/C153911025
concepts[3].level	1
concepts[3].score	0.5993241667747498
concepts[3].wikidata	https://www.wikidata.org/wiki/Q7202
concepts[3].display_name	Molecular biology
concepts[4].id	https://openalex.org/C206936463
concepts[4].level	4
concepts[4].score	0.591853141784668
concepts[4].wikidata	https://www.wikidata.org/wiki/Q634179
concepts[4].display_name	Breakpoint
concepts[5].id	https://openalex.org/C2992511266
concepts[5].level	3
concepts[5].score	0.5608622431755066
concepts[5].wikidata	https://www.wikidata.org/wiki/Q1093098
concepts[5].display_name	Gene rearrangement
concepts[6].id	https://openalex.org/C54355233
concepts[6].level	1
concepts[6].score	0.498460054397583
concepts[6].wikidata	https://www.wikidata.org/wiki/Q7162
concepts[6].display_name	Genetics
concepts[7].id	https://openalex.org/C36823959
concepts[7].level	3
concepts[7].score	0.42174461483955383
concepts[7].wikidata	https://www.wikidata.org/wiki/Q373027
concepts[7].display_name	Exon
concepts[8].id	https://openalex.org/C81089528
concepts[8].level	3
concepts[8].score	0.4117826819419861
concepts[8].wikidata	https://www.wikidata.org/wiki/Q5134986
concepts[8].display_name	clone (Java method)
concepts[9].id	https://openalex.org/C138626823
concepts[9].level	3
concepts[9].score	0.3903762102127075
concepts[9].wikidata	https://www.wikidata.org/wiki/Q916504
concepts[9].display_name	Chromosomal translocation
concepts[10].id	https://openalex.org/C113646796
concepts[10].level	4
concepts[10].score	0.37660500407218933
concepts[10].wikidata	https://www.wikidata.org/wiki/Q50263283
concepts[10].display_name	Recombination-activating gene
concepts[11].id	https://openalex.org/C30481170
concepts[11].level	3
concepts[11].score	0.3366544842720032
concepts[11].wikidata	https://www.wikidata.org/wiki/Q37748
concepts[11].display_name	Chromosome
concepts[12].id	https://openalex.org/C156695909
concepts[12].level	3
concepts[12].score	0.3348262310028076
concepts[12].wikidata	https://www.wikidata.org/wiki/Q3373825
concepts[12].display_name	Recombination
concepts[13].id	https://openalex.org/C104317684
concepts[13].level	2
concepts[13].score	0.31282392144203186
concepts[13].wikidata	https://www.wikidata.org/wiki/Q7187
concepts[13].display_name	Gene
keywords[0].id	https://openalex.org/keywords/fluorescence-in-situ-hybridization
keywords[0].score	0.7731142044067383
keywords[0].display_name	Fluorescence in situ hybridization
keywords[1].id	https://openalex.org/keywords/biology
keywords[1].score	0.7162935733795166
keywords[1].display_name	Biology
keywords[2].id	https://openalex.org/keywords/recombination-signal-sequences
keywords[2].score	0.7067198753356934
keywords[2].display_name	Recombination signal sequences
keywords[3].id	https://openalex.org/keywords/molecular-biology
keywords[3].score	0.5993241667747498
keywords[3].display_name	Molecular biology
keywords[4].id	https://openalex.org/keywords/breakpoint
keywords[4].score	0.591853141784668
keywords[4].display_name	Breakpoint
keywords[5].id	https://openalex.org/keywords/gene-rearrangement
keywords[5].score	0.5608622431755066
keywords[5].display_name	Gene rearrangement
keywords[6].id	https://openalex.org/keywords/genetics
keywords[6].score	0.498460054397583
keywords[6].display_name	Genetics
keywords[7].id	https://openalex.org/keywords/exon
keywords[7].score	0.42174461483955383
keywords[7].display_name	Exon
keywords[8].id	https://openalex.org/keywords/clone
keywords[8].score	0.4117826819419861
keywords[8].display_name	clone (Java method)
keywords[9].id	https://openalex.org/keywords/chromosomal-translocation
keywords[9].score	0.3903762102127075
keywords[9].display_name	Chromosomal translocation
keywords[10].id	https://openalex.org/keywords/recombination-activating-gene
keywords[10].score	0.37660500407218933
keywords[10].display_name	Recombination-activating gene
keywords[11].id	https://openalex.org/keywords/chromosome
keywords[11].score	0.3366544842720032
keywords[11].display_name	Chromosome
keywords[12].id	https://openalex.org/keywords/recombination
keywords[12].score	0.3348262310028076
keywords[12].display_name	Recombination
keywords[13].id	https://openalex.org/keywords/gene
keywords[13].score	0.31282392144203186
keywords[13].display_name	Gene
language	en
locations[0].id	doi:10.1016/j.jmoldx.2018.02.005
locations[0].is_oa	True
locations[0].source.id	https://openalex.org/S48180145
locations[0].source.issn	1525-1578, 1943-7811
locations[0].source.type	journal
locations[0].source.is_oa	False
locations[0].source.issn_l	1525-1578
locations[0].source.is_core	True
locations[0].source.is_in_doaj	False
locations[0].source.display_name	Journal of Molecular Diagnostics
locations[0].source.host_organization	https://openalex.org/P4310320990
locations[0].source.host_organization_name	Elsevier BV
locations[0].source.host_organization_lineage	https://openalex.org/P4310320990
locations[0].license
locations[0].pdf_url	http://jmd.amjpathol.org/article/S1525157817304129/pdf
locations[0].version	publishedVersion
locations[0].raw_type	journal-article
locations[0].license_id
locations[0].is_accepted	True
locations[0].is_published	True
locations[0].raw_source_name	The Journal of Molecular Diagnostics
locations[0].landing_page_url	https://doi.org/10.1016/j.jmoldx.2018.02.005
locations[1].id	pmid:29957452
locations[1].is_oa	False
locations[1].source.id	https://openalex.org/S4306525036
locations[1].source.issn
locations[1].source.type	repository
locations[1].source.is_oa	False
locations[1].source.issn_l
locations[1].source.is_core	False
locations[1].source.is_in_doaj	False
locations[1].source.display_name	PubMed
locations[1].source.host_organization	https://openalex.org/I1299303238
locations[1].source.host_organization_name	National Institutes of Health
locations[1].source.host_organization_lineage	https://openalex.org/I1299303238
locations[1].license
locations[1].pdf_url
locations[1].version	publishedVersion
locations[1].raw_type
locations[1].license_id
locations[1].is_accepted	True
locations[1].is_published	True
locations[1].raw_source_name	The Journal of molecular diagnostics : JMD
locations[1].landing_page_url	https://pubmed.ncbi.nlm.nih.gov/29957452
locations[2].id	pmh:oai:eprints.lib.hokudai.ac.jp:2115/74830
locations[2].is_oa	True
locations[2].source.id	https://openalex.org/S4306400549
locations[2].source.issn
locations[2].source.type	repository
locations[2].source.is_oa	False
locations[2].source.issn_l
locations[2].source.is_core	False
locations[2].source.is_in_doaj	False
locations[2].source.display_name	Hokkaido University Collection of Scholarly and Academic Papers (Hokkaido University)
locations[2].source.host_organization	https://openalex.org/I205349734
locations[2].source.host_organization_name	Hokkaido University
locations[2].source.host_organization_lineage	https://openalex.org/I205349734
locations[2].license	cc-by-nc-nd
locations[2].pdf_url
locations[2].version	submittedVersion
locations[2].raw_type	article (author version)
locations[2].license_id	https://openalex.org/licenses/cc-by-nc-nd
locations[2].is_accepted	False
locations[2].is_published	False
locations[2].raw_source_name
locations[2].landing_page_url	http://hdl.handle.net/2115/74830
indexed_in	crossref, pubmed
authorships[0].author.id	https://openalex.org/A5034787548
authorships[0].author.orcid
authorships[0].author.display_name	Junichi Hashiguchi
authorships[0].countries	JP
authorships[0].affiliations[0].institution_ids	https://openalex.org/I205349734
authorships[0].affiliations[0].raw_affiliation_string	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[0].institutions[0].id	https://openalex.org/I205349734
authorships[0].institutions[0].ror	https://ror.org/02e16g702
authorships[0].institutions[0].type	education
authorships[0].institutions[0].lineage	https://openalex.org/I205349734
authorships[0].institutions[0].country_code	JP
authorships[0].institutions[0].display_name	Hokkaido University
authorships[0].author_position	first
authorships[0].raw_author_name	Junichi Hashiguchi
authorships[0].is_corresponding	False
authorships[0].raw_affiliation_strings	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[1].author.id	https://openalex.org/A5049775425
authorships[1].author.orcid	https://orcid.org/0000-0001-9267-2864
authorships[1].author.display_name	Masahiro Onozawa
authorships[1].countries	JP
authorships[1].affiliations[0].institution_ids	https://openalex.org/I205349734
authorships[1].affiliations[0].raw_affiliation_string	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[1].institutions[0].id	https://openalex.org/I205349734
authorships[1].institutions[0].ror	https://ror.org/02e16g702
authorships[1].institutions[0].type	education
authorships[1].institutions[0].lineage	https://openalex.org/I205349734
authorships[1].institutions[0].country_code	JP
authorships[1].institutions[0].display_name	Hokkaido University
authorships[1].author_position	middle
authorships[1].raw_author_name	Masahiro Onozawa
authorships[1].is_corresponding	True
authorships[1].raw_affiliation_strings	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[2].author.id	https://openalex.org/A5090285695
authorships[2].author.orcid	https://orcid.org/0000-0003-4367-8818
authorships[2].author.display_name	Satoshi Oguri
authorships[2].countries	JP
authorships[2].affiliations[0].institution_ids	https://openalex.org/I4210141669
authorships[2].affiliations[0].raw_affiliation_string	Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Sapporo, Japan
authorships[2].institutions[0].id	https://openalex.org/I4210141669
authorships[2].institutions[0].ror	https://ror.org/0419drx70
authorships[2].institutions[0].type	healthcare
authorships[2].institutions[0].lineage	https://openalex.org/I4210141669
authorships[2].institutions[0].country_code	JP
authorships[2].institutions[0].display_name	Hokkaido University Hospital
authorships[2].author_position	middle
authorships[2].raw_author_name	Satoshi Oguri
authorships[2].is_corresponding	False
authorships[2].raw_affiliation_strings	Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Sapporo, Japan
authorships[3].author.id	https://openalex.org/A5091186581
authorships[3].author.orcid	https://orcid.org/0000-0002-5220-9522
authorships[3].author.display_name	Shinichi Fujisawa
authorships[3].countries	JP
authorships[3].affiliations[0].institution_ids	https://openalex.org/I4210141669
authorships[3].affiliations[0].raw_affiliation_string	Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Sapporo, Japan
authorships[3].institutions[0].id	https://openalex.org/I4210141669
authorships[3].institutions[0].ror	https://ror.org/0419drx70
authorships[3].institutions[0].type	healthcare
authorships[3].institutions[0].lineage	https://openalex.org/I4210141669
authorships[3].institutions[0].country_code	JP
authorships[3].institutions[0].display_name	Hokkaido University Hospital
authorships[3].author_position	middle
authorships[3].raw_author_name	Shinichi Fujisawa
authorships[3].is_corresponding	False
authorships[3].raw_affiliation_strings	Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Sapporo, Japan
authorships[4].author.id	https://openalex.org/A5110054523
authorships[4].author.orcid
authorships[4].author.display_name	Masahisa Tsuji
authorships[4].countries	JP
authorships[4].affiliations[0].institution_ids	https://openalex.org/I4210106602
authorships[4].affiliations[0].raw_affiliation_string	Chromosome Science Lab, Sapporo, Japan
authorships[4].institutions[0].id	https://openalex.org/I4210106602
authorships[4].institutions[0].ror	https://ror.org/0113nqq98
authorships[4].institutions[0].type	archive
authorships[4].institutions[0].lineage	https://openalex.org/I4210106602
authorships[4].institutions[0].country_code	JP
authorships[4].institutions[0].display_name	Sapporo Science Center
authorships[4].author_position	middle
authorships[4].raw_author_name	Masahisa Tsuji
authorships[4].is_corresponding	False
authorships[4].raw_affiliation_strings	Chromosome Science Lab, Sapporo, Japan
authorships[5].author.id	https://openalex.org/A5101613098
authorships[5].author.orcid	https://orcid.org/0000-0002-1241-1961
authorships[5].author.display_name	Kohei Okada
authorships[5].countries	JP
authorships[5].affiliations[0].institution_ids	https://openalex.org/I205349734
authorships[5].affiliations[0].raw_affiliation_string	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[5].institutions[0].id	https://openalex.org/I205349734
authorships[5].institutions[0].ror	https://ror.org/02e16g702
authorships[5].institutions[0].type	education
authorships[5].institutions[0].lineage	https://openalex.org/I205349734
authorships[5].institutions[0].country_code	JP
authorships[5].institutions[0].display_name	Hokkaido University
authorships[5].author_position	middle
authorships[5].raw_author_name	Kohei Okada
authorships[5].is_corresponding	False
authorships[5].raw_affiliation_strings	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[6].author.id	https://openalex.org/A5047706524
authorships[6].author.orcid	https://orcid.org/0000-0002-8602-6054
authorships[6].author.display_name	Masao Nakagawa
authorships[6].countries	JP
authorships[6].affiliations[0].institution_ids	https://openalex.org/I205349734
authorships[6].affiliations[0].raw_affiliation_string	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[6].institutions[0].id	https://openalex.org/I205349734
authorships[6].institutions[0].ror	https://ror.org/02e16g702
authorships[6].institutions[0].type	education
authorships[6].institutions[0].lineage	https://openalex.org/I205349734
authorships[6].institutions[0].country_code	JP
authorships[6].institutions[0].display_name	Hokkaido University
authorships[6].author_position	middle
authorships[6].raw_author_name	Masao Nakagawa
authorships[6].is_corresponding	False
authorships[6].raw_affiliation_strings	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[7].author.id	https://openalex.org/A5026708269
authorships[7].author.orcid	https://orcid.org/0000-0001-9489-9704
authorships[7].author.display_name	Daigo Hashimoto
authorships[7].countries	JP
authorships[7].affiliations[0].institution_ids	https://openalex.org/I205349734
authorships[7].affiliations[0].raw_affiliation_string	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[7].institutions[0].id	https://openalex.org/I205349734
authorships[7].institutions[0].ror	https://ror.org/02e16g702
authorships[7].institutions[0].type	education
authorships[7].institutions[0].lineage	https://openalex.org/I205349734
authorships[7].institutions[0].country_code	JP
authorships[7].institutions[0].display_name	Hokkaido University
authorships[7].author_position	middle
authorships[7].raw_author_name	Daigo Hashimoto
authorships[7].is_corresponding	False
authorships[7].raw_affiliation_strings	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[8].author.id	https://openalex.org/A5008609928
authorships[8].author.orcid
authorships[8].author.display_name	Kaoru Kahata
authorships[8].countries	JP
authorships[8].affiliations[0].institution_ids	https://openalex.org/I205349734
authorships[8].affiliations[0].raw_affiliation_string	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[8].institutions[0].id	https://openalex.org/I205349734
authorships[8].institutions[0].ror	https://ror.org/02e16g702
authorships[8].institutions[0].type	education
authorships[8].institutions[0].lineage	https://openalex.org/I205349734
authorships[8].institutions[0].country_code	JP
authorships[8].institutions[0].display_name	Hokkaido University
authorships[8].author_position	middle
authorships[8].raw_author_name	Kaoru Kahata
authorships[8].is_corresponding	False
authorships[8].raw_affiliation_strings	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[9].author.id	https://openalex.org/A5064182775
authorships[9].author.orcid	https://orcid.org/0000-0001-7455-5824
authorships[9].author.display_name	Takeshi Kondo
authorships[9].countries	JP
authorships[9].affiliations[0].institution_ids	https://openalex.org/I205349734
authorships[9].affiliations[0].raw_affiliation_string	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[9].institutions[0].id	https://openalex.org/I205349734
authorships[9].institutions[0].ror	https://ror.org/02e16g702
authorships[9].institutions[0].type	education
authorships[9].institutions[0].lineage	https://openalex.org/I205349734
authorships[9].institutions[0].country_code	JP
authorships[9].institutions[0].display_name	Hokkaido University
authorships[9].author_position	middle
authorships[9].raw_author_name	Takeshi Kondo
authorships[9].is_corresponding	False
authorships[9].raw_affiliation_strings	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[10].author.id	https://openalex.org/A5103481566
authorships[10].author.orcid
authorships[10].author.display_name	Chikara Shimizu
authorships[10].countries	JP
authorships[10].affiliations[0].institution_ids	https://openalex.org/I4210141669
authorships[10].affiliations[0].raw_affiliation_string	Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Sapporo, Japan
authorships[10].institutions[0].id	https://openalex.org/I4210141669
authorships[10].institutions[0].ror	https://ror.org/0419drx70
authorships[10].institutions[0].type	healthcare
authorships[10].institutions[0].lineage	https://openalex.org/I4210141669
authorships[10].institutions[0].country_code	JP
authorships[10].institutions[0].display_name	Hokkaido University Hospital
authorships[10].author_position	middle
authorships[10].raw_author_name	Chikara Shimizu
authorships[10].is_corresponding	False
authorships[10].raw_affiliation_strings	Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Sapporo, Japan
authorships[11].author.id	https://openalex.org/A5041455800
authorships[11].author.orcid	https://orcid.org/0000-0002-0941-271X
authorships[11].author.display_name	Takanori Teshima
authorships[11].countries	JP
authorships[11].affiliations[0].institution_ids	https://openalex.org/I205349734
authorships[11].affiliations[0].raw_affiliation_string	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
authorships[11].institutions[0].id	https://openalex.org/I205349734
authorships[11].institutions[0].ror	https://ror.org/02e16g702
authorships[11].institutions[0].type	education
authorships[11].institutions[0].lineage	https://openalex.org/I205349734
authorships[11].institutions[0].country_code	JP
authorships[11].institutions[0].display_name	Hokkaido University
authorships[11].author_position	last
authorships[11].raw_author_name	Takanori Teshima
authorships[11].is_corresponding	False
authorships[11].raw_affiliation_strings	Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan
has_content.pdf	True
has_content.grobid_xml	True
is_paratext	False
open_access.is_oa	True
open_access.oa_url	http://jmd.amjpathol.org/article/S1525157817304129/pdf
open_access.oa_status	bronze
open_access.any_repository_has_fulltext	False
created_date	2025-10-10T00:00:00
display_name	Development of a Fluorescence in Situ Hybridization Probe for Detecting IKZF1 Deletion Mutations in Patients with Acute Lymphoblastic Leukemia
has_fulltext	True
is_retracted	False
updated_date	2025-11-06T03:46:38.306776
primary_topic.id	https://openalex.org/T10950
primary_topic.field.id	https://openalex.org/fields/27
primary_topic.field.display_name	Medicine
primary_topic.score	1.0
primary_topic.domain.id	https://openalex.org/domains/4
primary_topic.domain.display_name	Health Sciences
primary_topic.subfield.id	https://openalex.org/subfields/2739
primary_topic.subfield.display_name	Public Health, Environmental and Occupational Health
primary_topic.display_name	Acute Lymphoblastic Leukemia research
related_works	https://openalex.org/W4385687889, https://openalex.org/W4386762942, https://openalex.org/W3169662407, https://openalex.org/W4200392269, https://openalex.org/W2065568155, https://openalex.org/W2555258765, https://openalex.org/W2500822946, https://openalex.org/W2188920098, https://openalex.org/W95963776, https://openalex.org/W2122688151
cited_by_count	5
counts_by_year[0].year	2024
counts_by_year[0].cited_by_count	1
counts_by_year[1].year	2023
counts_by_year[1].cited_by_count	2
counts_by_year[2].year	2020
counts_by_year[2].cited_by_count	1
counts_by_year[3].year	2018
counts_by_year[3].cited_by_count	1
locations_count	3
best_oa_location.id	doi:10.1016/j.jmoldx.2018.02.005
best_oa_location.is_oa	True
best_oa_location.source.id	https://openalex.org/S48180145
best_oa_location.source.issn	1525-1578, 1943-7811
best_oa_location.source.type	journal
best_oa_location.source.is_oa	False
best_oa_location.source.issn_l	1525-1578
best_oa_location.source.is_core	True
best_oa_location.source.is_in_doaj	False
best_oa_location.source.display_name	Journal of Molecular Diagnostics
best_oa_location.source.host_organization	https://openalex.org/P4310320990
best_oa_location.source.host_organization_name	Elsevier BV
best_oa_location.source.host_organization_lineage	https://openalex.org/P4310320990
best_oa_location.license
best_oa_location.pdf_url	http://jmd.amjpathol.org/article/S1525157817304129/pdf
best_oa_location.version	publishedVersion
best_oa_location.raw_type	journal-article
best_oa_location.license_id
best_oa_location.is_accepted	True
best_oa_location.is_published	True
best_oa_location.raw_source_name	The Journal of Molecular Diagnostics
best_oa_location.landing_page_url	https://doi.org/10.1016/j.jmoldx.2018.02.005
primary_location.id	doi:10.1016/j.jmoldx.2018.02.005
primary_location.is_oa	True
primary_location.source.id	https://openalex.org/S48180145
primary_location.source.issn	1525-1578, 1943-7811
primary_location.source.type	journal
primary_location.source.is_oa	False
primary_location.source.issn_l	1525-1578
primary_location.source.is_core	True
primary_location.source.is_in_doaj	False
primary_location.source.display_name	Journal of Molecular Diagnostics
primary_location.source.host_organization	https://openalex.org/P4310320990
primary_location.source.host_organization_name	Elsevier BV
primary_location.source.host_organization_lineage	https://openalex.org/P4310320990
primary_location.license
primary_location.pdf_url	http://jmd.amjpathol.org/article/S1525157817304129/pdf
primary_location.version	publishedVersion
primary_location.raw_type	journal-article
primary_location.license_id
primary_location.is_accepted	True
primary_location.is_published	True
primary_location.raw_source_name	The Journal of Molecular Diagnostics
primary_location.landing_page_url	https://doi.org/10.1016/j.jmoldx.2018.02.005
publication_date	2018-06-25
publication_year	2018
referenced_works	https://openalex.org/W2048365283, https://openalex.org/W2119967034, https://openalex.org/W2082824785, https://openalex.org/W2040329520, https://openalex.org/W2025696725, https://openalex.org/W2084692856, https://openalex.org/W2090946356, https://openalex.org/W2136334823, https://openalex.org/W1919084303, https://openalex.org/W81453212, https://openalex.org/W2740576382, https://openalex.org/W2088615937, https://openalex.org/W2160913805, https://openalex.org/W2074070601, https://openalex.org/W2045750237, https://openalex.org/W2066927043, https://openalex.org/W2151292007, https://openalex.org/W2213672275, https://openalex.org/W2080611686, https://openalex.org/W2087320673, https://openalex.org/W2588472739, https://openalex.org/W2144920932, https://openalex.org/W2144729402, https://openalex.org/W2531341692, https://openalex.org/W2234728088, https://openalex.org/W2746186765, https://openalex.org/W2586897381
referenced_works_count	27
abstract_inverted_index
cited_by_percentile_year.max	96
cited_by_percentile_year.min	89
corresponding_author_ids	https://openalex.org/A5049775425
countries_distinct_count	1
institutions_distinct_count	12
corresponding_institution_ids	https://openalex.org/I205349734
sustainable_development_goals[0].id	https://metadata.un.org/sdg/14
sustainable_development_goals[0].score	0.5899999737739563
sustainable_development_goals[0].display_name	Life below water
citation_normalized_percentile.value	0.69650976
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	False