Development of an Antimicrobial Peptide-based Biosensor for the Monitoring of Bacterial Contaminations Article Swipe
Donatella Albanese
,
Francesca Garofalo
,
Roberto Pilloton
,
Salvatore Capo
,
Francesca Malvano
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.3303/cet1975011
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.3303/cet1975011
Nisin is a cationic amphiphilic peptide consisting of 34 amino acids with a cluster of hydrophobic residues at the N-terminus and hydrophilic residues at the C-terminus. The mechanism of its action is based on its ability to attach to the bacteria cell membrane before to then cause cell lysis. This antimicrobial peptide was used as biological molecule for the development of a novel impedimetric label-free biosensor for the monitoring of bacterial contamination. The binding affinities of Nisin immobilized with its N-terminus and C-terminus were compared, highlighting the capability of the last configuration to obtain the best analytical performance of the developed biosensor when non-pathogenic Escherichia Coli O157:H7 and Listeria innocua cells were investigated.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doaj.org/article/db1f094420634c218d8918db7c55beb2
- OA Status
- green
- Cited By
- 7
- Related Works
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- OpenAlex ID
- https://openalex.org/W2957950546
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2957950546Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3303/cet1975011Digital Object Identifier
- Title
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Development of an Antimicrobial Peptide-based Biosensor for the Monitoring of Bacterial ContaminationsWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2019Year of publication
- Publication date
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2019-06-01Full publication date if available
- Authors
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Donatella Albanese, Francesca Garofalo, Roberto Pilloton, Salvatore Capo, Francesca MalvanoList of authors in order
- Landing page
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https://doaj.org/article/db1f094420634c218d8918db7c55beb2Publisher landing page
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
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https://doaj.org/article/db1f094420634c218d8918db7c55beb2Direct OA link when available
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Biosensor, Antimicrobial, Peptide, Antimicrobial peptides, Chromatography, Chemistry, Microbiology, Nanotechnology, Biology, Biochemistry, Materials scienceTop concepts (fields/topics) attached by OpenAlex
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7Total citation count in OpenAlex
- Citations by year (recent)
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2025: 1, 2024: 1, 2022: 2, 2021: 2, 2020: 1Per-year citation counts (last 5 years)
- Related works (count)
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10Other works algorithmically related by OpenAlex
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