Development of diagnostic and point of care assays for a gammaherpesvirus infecting koalas Article Swipe
YOU?
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· 2023
· Open Access
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· DOI: https://doi.org/10.1371/journal.pone.0286407
The recent listing of koala populations as endangered across much of their range has highlighted the need for better management interventions. Disease is a key threat to koala populations but currently there is no information across the threatened populations on the distribution or impact of a gammaherpesvirus, phascolarctid gammaherpesvirus 1 (PhaHV-1). PhaHV-1 is known to infect koalas in southern populations which are, at present, not threatened. Current testing for PhaHV-1 involves lengthy laboratory techniques that do not permit quantification of viral load. In order to better understand distribution, prevalence and impacts of PhaHV-1 infections across koala populations, diagnostic and rapid point of care tests are required. We have developed two novel assays, a qPCR assay and an isothermal assay, that will enable researchers, clinicians and wildlife managers to reliably and rapidly test for PhaHV-1 in koalas. The ability to rapidly diagnose and quantify viral load will aid quarantine practices, inform translocation management and guide research into the clinical significance and impacts of PhaHV-1 infection in koalas.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1371/journal.pone.0286407
- OA Status
- gold
- Cited By
- 9
- References
- 36
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4378977414
Raw OpenAlex JSON
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https://openalex.org/W4378977414Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1371/journal.pone.0286407Digital Object Identifier
- Title
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Development of diagnostic and point of care assays for a gammaherpesvirus infecting koalasWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-06-01Full publication date if available
- Authors
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Belinda Wright, Martina Jelocnik, Andrea Casteriano, Yasmine S. S. Muir, Alistair R. Legione, Paola K. Vaz, Joanne M. Devlin, Damien P. HigginsList of authors in order
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https://doi.org/10.1371/journal.pone.0286407Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.1371/journal.pone.0286407Direct OA link when available
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Endangered species, Biology, Threatened species, Wildlife, Phascolarctos cinereus, Quarantine, Diagnostic test, Point-of-care testing, Zoology, Ecology, Population, Immunology, Medicine, Environmental health, Veterinary medicine, HabitatTop concepts (fields/topics) attached by OpenAlex
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9Total citation count in OpenAlex
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2025: 4, 2024: 5Per-year citation counts (last 5 years)
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36Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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