Diagnostic accuracy of non-invasive investigations for coronary artery disease in hypertensive patients: A meta-analysis Article Swipe
Ibadete Bytyçi
,
Sefer Bytyqi
,
Gani Abazi
,
Gani Bajraktari
,
Michael Y. Henein
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.5114/aoms/188782
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.5114/aoms/188782
Introduction Non-invasive assessment of coronary artery disease (CAD) in patients with hypertensive heart disease is still a major clinical challenge. The aim of this meta-analysis was to evaluate the diagnostic accuracy of different non-invasive techniques in detecting significant (>50%) CAD in hypertensive patients. Material and methods We systematically searched selected electronic databases from inception until 21st February 2024. Main clinical endpoint was the diagnostic accuracy of non-invasive investigations including exercise electrocardiography test (EET), stress echocardiography (SE) and myocardial perfusion imaging (MPI). The random effects summary receiver operating characteristic analysis was performed. Results Twenty-five papers with a total of 3812 patients with systemic hypertension and suspected significant CAD were finally included in the meta-analysis. The diagnostic accuracy of SE was the highest compared to the two other investigations (85%, 72%, 53%, p<0.05 for all). SE had higher sensitivity 85% (83-87%) and specificity 81% (79-83%) compared to MPI [Sensitivity 81% (77-83%), specificity 64% (59-68%)] and EET [Sensitivity: 53% (50-65%) and specificity 51% (47-54%)]. All three tested investigations had higher accuracy in patients with multivessel disease compared to those with single-vessel disease (p<0.05 for all). The diagnostic accuracy of SE and MPI was not significantly impacted by left ventricular hypertrophy (p>0.05 for both), compared to EET which was lower in patients with hypertrophy compared to those without (41% vs. 58%, p=0.03). These results were consistent irrespective of the stress echo modality, physical, exercise or pharmacological (p>0.05). Conclusions This meta-analysis reveals the powerful diagnostic value of stress echocardiography in detecting significant coronary artery disease in hypertension patients.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.5114/aoms/188782
- https://www.archivesofmedicalscience.com/pdf-188782-110982?filename=Diagnostic accuracy of.pdf
- OA Status
- gold
- Cited By
- 1
- References
- 25
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4399379669
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Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4399379669Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.5114/aoms/188782Digital Object Identifier
- Title
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Diagnostic accuracy of non-invasive investigations for coronary artery disease in hypertensive patients: A meta-analysisWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-06-06Full publication date if available
- Authors
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Ibadete Bytyçi, Sefer Bytyqi, Gani Abazi, Gani Bajraktari, Michael Y. HeneinList of authors in order
- Landing page
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https://doi.org/10.5114/aoms/188782Publisher landing page
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https://www.archivesofmedicalscience.com/pdf-188782-110982?filename=Diagnostic accuracy of.pdfDirect link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.archivesofmedicalscience.com/pdf-188782-110982?filename=Diagnostic accuracy of.pdfDirect OA link when available
- Concepts
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Medicine, Coronary artery disease, Diagnostic accuracy, Cardiology, Internal medicine, Meta-analysis, Left ventricular hypertrophy, Receiver operating characteristic, Muscle hypertrophy, Perfusion, Radiology, Blood pressureTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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