Diagnostic value of the creatine kinase-MB/creatine kinase and neutrophil/lymphocyte ratios in acute myocardial infarction Article Swipe
Yin Liu
,
Xiaolei Tang
,
Yong Ni
,
Li-Zhong Duan
,
Feng-Jun Jing
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1186/s13019-024-02740-9
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1186/s13019-024-02740-9
Objective To investigate the clinical significance of the creatine kinase (CK)-MB/total CK ratio, neutrophil/lymphocyte ratio (NLR) and red blood cell distribution width in acute myocardial infarction (AMI). Methods A retrospective analysis was conducted of 196 AMI cases from our hospital’s cardiology department; healthy people were selected over the same period as the control. The two groups’ test indexes were compared through multivariate logistic regression analysis to screen for AMI risk factors; the receiver operating characteristic (ROC) curve was used to evaluate their AMI predictive values. Results The serum CK, CK-MB, CK index, neutrophils and NLR values in the AMI group were significantly higher compared with those in the control group ( p < 0.05); however, the levels of serum lymphocytes were significantly lower compared with those in the control group ( p < 0.05). Multivariate logistic regression analysis showed that elevated CK-MB and NLR levels were risk factors for AMI ( p < 0.05). The ROC curve showed that the area under the curve of the NLR and CK levels were 0.917 and 0.594, respectively. Conclusion The CK index and NLR have a clinical predicting value for AMI and could be used as a clinical auxiliary diagnostic index for the assessment of patients with AMI.
Related Topics
Concepts
Medicine
Receiver operating characteristic
Creatine kinase
Internal medicine
Logistic regression
Neutrophil to lymphocyte ratio
Myocardial infarction
Creatine
Lymphocyte
Cardiology
Red blood cell distribution width
Gastroenterology
Area under the curve
Retrospective cohort study
Multivariate analysis
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1186/s13019-024-02740-9
- https://cardiothoracicsurgery.biomedcentral.com/counter/pdf/10.1186/s13019-024-02740-9
- OA Status
- gold
- Cited By
- 8
- References
- 15
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4394847611
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4394847611Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1186/s13019-024-02740-9Digital Object Identifier
- Title
-
Diagnostic value of the creatine kinase-MB/creatine kinase and neutrophil/lymphocyte ratios in acute myocardial infarctionWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-04-16Full publication date if available
- Authors
-
Yin Liu, Xiaolei Tang, Yong Ni, Li-Zhong Duan, Feng-Jun JingList of authors in order
- Landing page
-
https://doi.org/10.1186/s13019-024-02740-9Publisher landing page
- PDF URL
-
https://cardiothoracicsurgery.biomedcentral.com/counter/pdf/10.1186/s13019-024-02740-9Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://cardiothoracicsurgery.biomedcentral.com/counter/pdf/10.1186/s13019-024-02740-9Direct OA link when available
- Concepts
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Medicine, Receiver operating characteristic, Creatine kinase, Internal medicine, Logistic regression, Neutrophil to lymphocyte ratio, Myocardial infarction, Creatine, Lymphocyte, Cardiology, Red blood cell distribution width, Gastroenterology, Area under the curve, Retrospective cohort study, Multivariate analysisTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
8Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 7, 2024: 1Per-year citation counts (last 5 years)
- References (count)
-
15Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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