Differential Effects of Toll-Like Receptor Signaling on the Activation of Immune Responses in the Upper Respiratory Tract Article Swipe
Meiyi Xu
,
Ning Li
,
Xin Fan
,
Ya Zhou
,
Shuai Bi
,
Adong Shen
,
Beinan Wang
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1128/spectrum.01144-21
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1128/spectrum.01144-21
Agonists of TLRs are potential adjuvant candidates for mucosal vaccination. We demonstrated that the TLR-mediated inflammatory and antibody responses in the URT of SPF mice exposed to extracellular TLR agonists were substantially restricted.
Related Topics
Concepts
Immune system
Agonist
TLR2
TLR4
Immunology
TLR3
TLR9
Toll-like receptor
Innate immune system
Adjuvant
Biology
Acquired immune system
Pattern recognition receptor
Receptor
Gene expression
Biochemistry
DNA methylation
Gene
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1128/spectrum.01144-21
- OA Status
- gold
- Cited By
- 3
- References
- 50
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4213428734
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4213428734Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1128/spectrum.01144-21Digital Object Identifier
- Title
-
Differential Effects of Toll-Like Receptor Signaling on the Activation of Immune Responses in the Upper Respiratory TractWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-02-23Full publication date if available
- Authors
-
Meiyi Xu, Ning Li, Xin Fan, Ya Zhou, Shuai Bi, Adong Shen, Beinan WangList of authors in order
- Landing page
-
https://doi.org/10.1128/spectrum.01144-21Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1128/spectrum.01144-21Direct OA link when available
- Concepts
-
Immune system, Agonist, TLR2, TLR4, Immunology, TLR3, TLR9, Toll-like receptor, Innate immune system, Adjuvant, Biology, Acquired immune system, Pattern recognition receptor, Receptor, Gene expression, Biochemistry, DNA methylation, GeneTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
3Total citation count in OpenAlex
- Citations by year (recent)
-
2024: 1, 2023: 2Per-year citation counts (last 5 years)
- References (count)
-
50Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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