Microbiology Spectrum • Vol 10 • No 1
Differential Effects of Toll-Like Receptor Signaling on the Activation of Immune Responses in the Upper Respiratory Tract
February 2022 • Meiyi Xu, Ning Li, Xin Fan, Ya Zhou, Shuai Bi, Adong Shen, Beinan Wang
Agonists of TLRs are potential adjuvant candidates for mucosal vaccination. We demonstrated that the TLR-mediated inflammatory and antibody responses in the URT of SPF mice exposed to extracellular TLR agonists were substantially restricted.