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Differentiating Tumor Recurrence and Pseudoprogression in Postoperative Gliomas Using Pseudo- continuous Arterial Spin Labeling (pCASL) Technique
October 2025 • Ping Liu, Yujie Chen, XinLei Ai, Weiyin Vivian Liu, Hongquan Zhu, Yu‐Jie Ding, Dong Liu, Tengfei Chao, Jiaxuan Zhang, Wenzhen Zhu
<title>Abstract</title> <bold>Objective:</bold> To assess whether the pCASL technique and its radiomics features can enhance the differentiation between tumor recurrence (TR) and pseudoprogression (PsP) in postoperative glioma patients. <bold>Methods: </bold>A retrospective study of 120 postoperative glioma patients (WHO Grade 2–4) from Tongji Hospital, Wuhan, was conducted. MRI data, including T1WI, T2WI, T2FLAIR, contrast-enhanced T1WI, and pCASL, were analyzed. Final diagnoses of TR or PsP were confirmed throug…