DIMENSIONALITY, PROXIES, AND PREDICTORS OF COGNITIVE RESERVE IN THE MANCHESTER LONGITUDINAL STUDY Article Swipe
In a sample of N=113 older adults (ages 62-86 years at MRI scan; 58.4% women) from the United Kingdom, we compared the dimensionality of general cognition before (COG) vs. after (COGr; cognitive reserve) residualization on global brain status (as indicated by brain volume loss, cerebral blood flow, and white matter lesion prevalence). Cognitive performance was assessed by 15 tasks spanning five domains: processing speed, fluid intelligence (e.g., spatial reasoning), crystallized intelligence (vocabulary), visuospatial memory, and verbal memory. Statistical tests were conducted in a series of structural factor analyses with progressive constraints on measurement invariance. Results showed that although COG and COGr were highly correlated (r =.84), item-factor loadings differed such that COGr more strongly emphasized fluid intelligence. We further examined differential associations of COG and COGr with 23 socio-demographic, health, and lifestyle variables in a series of regression models. Results from these latter tests showed consistent associations of education level, occupational class, and hobbies/interests as proxies both for COG and COGr. Difficulty with personal mobility was a salient risk factor for both COG and COGr, but only in models unadjusted for chronological age. In sum, results supported the role of intelligence as a potential compensatory factor for brain-related reductions in processing speed and memory. Efforts to preserve personal mobility and a diversity of hobbies and interests may serve as protective factors against brain-related reductions in cognitive performance.
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- Type
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- Language
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- https://doi.org/10.1093/geroni/igae098.3043
- OA Status
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https://openalex.org/W4405964510Canonical identifier for this work in OpenAlex
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https://doi.org/10.1093/geroni/igae098.3043Digital Object Identifier
- Title
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DIMENSIONALITY, PROXIES, AND PREDICTORS OF COGNITIVE RESERVE IN THE MANCHESTER LONGITUDINAL STUDYWork title
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articleOpenAlex work type
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enPrimary language
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2024Year of publication
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2024-12-01Full publication date if available
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Stephen AicheleList of authors in order
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https://doi.org/10.1093/geroni/igae098.3043Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.1093/geroni/igae098.3043Direct OA link when available
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Curse of dimensionality, Cognition, Longitudinal study, Psychology, Geography, Computer science, Statistics, Artificial intelligence, Mathematics, PsychiatryTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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| citation_normalized_percentile.value | 0.39026653 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |