Disease Burden and Treatment Patterns in Patients With Hidradenitis Suppurativa and Concomitant Arthritis: A Multicenter Case–Control Study Article Swipe
Patricia Garbayo‐Salmons
,
Alejandro Molina‐Leyva
,
Anna Porta‐Vilaró
,
Alberto Soto‐Moreno
,
Rosa Fornons‐Servent
,
Marta Gamissans
,
J. Garcías-Ladaria
,
Inés Gracia‐Darder
,
Gemma Martín‐Ezquerra
,
Júlia Verdaguer‐Faja
,
Verónica Mora‐Fernández
,
Rafael S. Aguayo‐Ortiz
,
Eva Vilarrasa
,
Emili Masferrer
,
O. Corral-Magaña
,
Loida Galvany
,
Albert Rodrigo‐Parés
,
Ester Saus
,
Mireia Moreno
,
Anna Carreras
,
Clara Feliu‐Hernàndez
,
V. Expósito‐Serrano
,
Miquel Ribera
,
Mireia Sàbat
,
Joan Calvet
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1111/ijd.70125
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1111/ijd.70125
Background The relationship between hidradenitis suppurativa ( HS) and arthritis is well‐established; however, the impact of their combined disease burden and the associated treatment pattern has not been determined yet. This study aimed to assess disease burden and therapeutic approaches in HS patients with and without arthritis and estimate arthritis prevalence and subtypes. Methods A multicenter, retrospective, case–control study of 272 adults (69 with HS and arthritis; 203 with HS only), drawn from a hospital‐based cohort of 3644 HS patients across 10 Spanish centers. Controls were matched 1:3 by sex, age, and HS duration. Statistical analysis included non‐parametric tests, logistic regression, and linear mixed‐effects models adjusted for confounders. Results HS patients with arthritis had higher rates of immune‐mediated diseases, including inflammatory bowel disease (odds ratio [ OR] 9.44, p < 0.0001) and psoriasis ( OR 2.99, p = 0.0038), higher Dermatology Life Quality Index ( DLQI) scores (6.30 vs. 4.03, p = 0.031), more dermatology visits (7.00 vs. 5.00, p = 0.0077), and greater biologic therapy use (72.07% vs. 39.90%, p < 0.0001). The prevalence of arthritis among HS patients was 1.70% (95% confidence interval [ CI] : 1.00%–2.70%), with spondyloarthritis being the most common subtype (66.6%). Conclusions HS patients with arthritis have a greater disease burden and higher biologic therapy utilization, emphasizing the need for interdisciplinary care and optimizing resources.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/ijd.70125
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijd.70125
- OA Status
- bronze
- References
- 21
- OpenAlex ID
- https://openalex.org/W4415690268
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4415690268Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1111/ijd.70125Digital Object Identifier
- Title
-
Disease Burden and Treatment Patterns in Patients With Hidradenitis Suppurativa and Concomitant Arthritis: A Multicenter Case–Control StudyWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-10-30Full publication date if available
- Authors
-
Patricia Garbayo‐Salmons, Alejandro Molina‐Leyva, Anna Porta‐Vilaró, Alberto Soto‐Moreno, Rosa Fornons‐Servent, Marta Gamissans, J. Garcías-Ladaria, Inés Gracia‐Darder, Gemma Martín‐Ezquerra, Júlia Verdaguer‐Faja, Verónica Mora‐Fernández, Rafael S. Aguayo‐Ortiz, Eva Vilarrasa, Emili Masferrer, O. Corral-Magaña, Loida Galvany, Albert Rodrigo‐Parés, Ester Saus, Mireia Moreno, Anna Carreras, Clara Feliu‐Hernàndez, V. Expósito‐Serrano, Miquel Ribera, Mireia Sàbat, Joan CalvetList of authors in order
- Landing page
-
https://doi.org/10.1111/ijd.70125Publisher landing page
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijd.70125Direct link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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bronzeOpen access status per OpenAlex
- OA URL
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijd.70125Direct OA link when available
- Cited by
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0Total citation count in OpenAlex
- References (count)
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21Number of works referenced by this work
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