Disseminated Mycobacterium kansasii and Mycobacterium avium complex co-infection in GATA2 mutated myelodysplastic syndrome: a case report Article Swipe
Sabrina E Newstead
,
Daniel Montelongo
,
Salika M. Shakir
,
Neeraja Swaminathan
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1177/20499361251359825
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1177/20499361251359825
A 79-year-old female diagnosed with myelodysplastic syndrome (MDS) and germline GATA2 mutation, on compassionate cobimetinib, was admitted with subacute cough and dyspnea. Chest imaging demonstrated a new, large, left hilar mass and consolidation with scattered diffuse mediastinal, supraclavicular, and hilar lymphadenopathy. A core biopsy of the right supraclavicular lymph node was performed. Acid-fast bacilli (AFB) cultures from both the lymph node and blood were positive, while all fungal cultures were negative. Two distinct AFB colonies were observed on solid media and identified as Mycobacterium avium complex and Mycobacterium kansasii. Disseminated non-tuberculous mycobacterial infections involving two distinct species are rare, pose treatment challenges, and may correlate with cobimetinib administration for MDS, as well as GATA2 germline mutations.
Related Topics
Concepts
Mycobacterium kansasii
Nontuberculous mycobacteria
Medicine
Mycobacterium
Mediastinal lymphadenopathy
Mycobacterium tuberculosis
Germline
Lymph node
Pathology
Biopsy
Tuberculosis
Biology
Biochemistry
Gene
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1177/20499361251359825
- OA Status
- gold
- References
- 17
- Related Works
- 10
- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://doi.org/10.1177/20499361251359825Digital Object Identifier
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Disseminated Mycobacterium kansasii and Mycobacterium avium complex co-infection in GATA2 mutated myelodysplastic syndrome: a case reportWork title
- Type
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articleOpenAlex work type
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enPrimary language
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2025Year of publication
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2025-07-01Full publication date if available
- Authors
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Sabrina E Newstead, Daniel Montelongo, Salika M. Shakir, Neeraja SwaminathanList of authors in order
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https://doi.org/10.1177/20499361251359825Publisher landing page
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goldOpen access status per OpenAlex
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https://doi.org/10.1177/20499361251359825Direct OA link when available
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Mycobacterium kansasii, Nontuberculous mycobacteria, Medicine, Mycobacterium, Mediastinal lymphadenopathy, Mycobacterium tuberculosis, Germline, Lymph node, Pathology, Biopsy, Tuberculosis, Biology, Biochemistry, GeneTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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