Dreadds: Use and application in behavioral neuroscience. Article Swipe
YOU?
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· 2021
· Open Access
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· DOI: https://doi.org/10.1037/bne0000433
Technological advances over the last decade are changing the face of behavioral neuroscience research. Here we review recent work on the use of one such transformative tool in behavioral neuroscience research, chemogenetics (or Designer Receptors Exclusively Activated by Designer Drugs, DREADDS). As transformative technologies such as DREADDs are introduced, applied, and refined, their utility in addressing complex questions about behavior and cognition becomes clear and exciting. In the behavioral neuroscience field, remarkable new findings now regularly appear as a result of the ability to monitor and intervene in neural processes with high anatomical precision as animals behave in complex task environments. As these new tools are applied to behavioral questions, individualized procedures for their use find their way into diverse labs. Thus, "tips of the trade" become important for wide dissemination not only for laboratories that are using the tools but also for those who are interested in incorporating them into their own work. Our aim is to provide an up-to-date perspective on how the DREADD technique is being used for research on learning and memory, decision making, and goal-directed behavior, as well as to provide suggestions and considerations for current and future users based on our collective experience. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
Related Topics
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1037/bne0000433
- OA Status
- hybrid
- Cited By
- 40
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4231157129
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4231157129Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1037/bne0000433Digital Object Identifier
- Title
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Dreadds: Use and application in behavioral neuroscience.Work title
- Type
-
reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2021Year of publication
- Publication date
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2021-04-01Full publication date if available
- Authors
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Kyle S. Smith, David J. Bucci, Bryan W. Luikart, Stephen V. MahlerList of authors in order
- Landing page
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https://doi.org/10.1037/bne0000433Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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hybridOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1037/bne0000433Direct OA link when available
- Concepts
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Neuroscience, PsycINFO, Transformative learning, Psychology, Perspective (graphical), Cognitive neuroscience, Behavioral neuroscience, Social neuroscience, Systems neuroscience, Cognitive science, Cognition, Computer science, MEDLINE, Social cognition, Biology, Pedagogy, Biochemistry, Oligodendrocyte, Central nervous system, Artificial intelligence, MyelinTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
40Total citation count in OpenAlex
- Citations by year (recent)
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2025: 11, 2024: 17, 2023: 4, 2022: 3, 2020: 2Per-year citation counts (last 5 years)
- Related works (count)
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10Other works algorithmically related by OpenAlex
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