Drug‐Coated versus Conventional Balloons to Improve Recanalization of a Coronary Chronic Total Occlusion after Failed Attempt: The Improved‐CTO Registry Article Swipe
Ignacio J. Amat‐Santos
,
Giorgio Marengo
,
Luiz F. Ybarra
,
José Díaz
,
Ander Regueiro
,
Alejandro Gutiérrez
,
Javier Martín‐Moreiras
,
Juan Pablo Sánchez-Luna
,
José Carlos González-Gutiérrez
,
Clara Fernández‐Cordón
,
Manuel Carrasco‐Moraleja
,
Stéphane Rinfret
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1155/2024/2797561
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1155/2024/2797561
Background . Chronic total occlusion (CTO) plaque modification (CTO‐PM) is often used for unsuccessful CTO interventions. Methods . A multicenter, prospective study included consecutive patients with failed CTO recanalization. At the end of the failed procedure, patients received either a conventional (CB) or drug‐coated balloon (DCB) for CTO‐PM at the operator’s discretion and underwent a new attempt of CTO recanalization ∼3 months later. Results . A total of 55 patients were enrolled (DCB: 22; CB: 33), with a median age of 66 years. The median J‐score was 3, and CCS angina classes III–IV were present in 45% of the patients. After the first CTO‐PCI attempt, no in‐hospital cardiac deaths were registered. The overall rate of in‐hospital myocardial infarction was 3.6%, without significant differences between the DCB and CB groups (4.5% after DCB vs 3.0% after CB, p = 0.999). The success rate of the second CTO‐PCI attempt was 86.8%, with a periprocedural complication rate of 5.7% and with an overall rate of in‐hospital complications of 24.5%, without significant differences between the 2 groups (13.6% in the DCB group vs 32.2% in the CB group, p = 0.195). Compared with CB, in the DCB group, the second CTO‐PCI required a shorter median fluoroscopy time (33 vs 60 min, p < 0.001), a lower contrast volume (170 vs 321 cc, p < 0.001), and a lower radiation dose (1.7 vs 3.3 Gy, p < 0.001). At 1‐year follow‐up, outcomes were comparable between the 2 strategies, target vessel failure occurred in 5.7% and major adverse cardiovascular events in 18.2% (13.6% in the DCB group vs 21.2% in the CB group, p = 0.494). Conclusions . PM after CTO recanalization failure is safe and warrants high success rates when a second attempt is performed. A DCB strategy for CTO‐PM does not seem to ensure higher success or better clinical outcomes, but its use was associated with simpler staged procedures. This trial is registered with NCT05158686 .
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1155/2024/2797561
- OA Status
- gold
- Cited By
- 3
- References
- 24
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4400665627
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4400665627Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1155/2024/2797561Digital Object Identifier
- Title
-
Drug‐Coated versus Conventional Balloons to Improve Recanalization of a Coronary Chronic Total Occlusion after Failed Attempt: The Improved‐CTO RegistryWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-01-01Full publication date if available
- Authors
-
Ignacio J. Amat‐Santos, Giorgio Marengo, Luiz F. Ybarra, José Díaz, Ander Regueiro, Alejandro Gutiérrez, Javier Martín‐Moreiras, Juan Pablo Sánchez-Luna, José Carlos González-Gutiérrez, Clara Fernández‐Cordón, Manuel Carrasco‐Moraleja, Stéphane RinfretList of authors in order
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https://doi.org/10.1155/2024/2797561Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1155/2024/2797561Direct OA link when available
- Concepts
-
Medicine, Conventional PCI, Fluoroscopy, Myocardial infarction, Coronary occlusion, Occlusion, Surgery, Balloon, Cardiology, Internal medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
3Total citation count in OpenAlex
- Citations by year (recent)
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2025: 2, 2024: 1Per-year citation counts (last 5 years)
- References (count)
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24Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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