Ductus venosus agenesis and fetal malformations: what can we expect? – a systematic review of the literature Article Swipe
Diana Rodrigues Pacheco
,
Otília Brandão
,
Nuno Montenegro
,
Alexandra Matias
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1515/jpm-2018-0163
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1515/jpm-2018-0163
Background The ductus venosus agenesis (DVA) is a rare condition with a variable prognosis that relies partly on the presence of associated conditions. The purpose of our study was to analyze the literature regarding the post-natal outcome of fetuses with DVA associated with fetal malformations, in order to discuss the best management options for couples. Methods We performed a systematic review of the literature of MEDLINE and SCOPUS electronic databases in a 25-year period from 1992 to September 2017. Methods We found 340 cases of DVA associated with fetal abnormalities. The most common chromosomal abnormalities were: monosomy X (12/48, 25%), trisomy 21 (11/48, 22.9%) and trisomy 18 (6/48, 12.5%). From the 340 cases with DVA, in 31 cases the umbilical venous shunt type was not reported. Of the fetuses, 60.8% (188/309) had an extrahepatic umbilical venous drainage while 39.2% (121/309) presented an intrahepatic connection. The DVA was associated in 71 cases (23.0%) with cardiac abnormalities, in 82 cases (26.5%) with extracardiac abnormalities and in 85 cases (27.5%) with both cardiac and extracardiac abnormalities. Conclusion DVA associated with both cardiac and extracardiac malformations may confer a poorer fetal outcome, a clinically relevant fact that should clarify what can be expected from this entity and help prenatal counseling.
Related Topics
Concepts
Ductus venosus
Medicine
Trisomy
Fetus
Agenesis
Pregnancy
Pediatrics
Obstetrics
Surgery
Biology
Genetics
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1515/jpm-2018-0163
- OA Status
- green
- Cited By
- 30
- References
- 28
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2883221306
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2883221306Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1515/jpm-2018-0163Digital Object Identifier
- Title
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Ductus venosus agenesis and fetal malformations: what can we expect? – a systematic review of the literatureWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2018Year of publication
- Publication date
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2018-06-27Full publication date if available
- Authors
-
Diana Rodrigues Pacheco, Otília Brandão, Nuno Montenegro, Alexandra MatiasList of authors in order
- Landing page
-
https://doi.org/10.1515/jpm-2018-0163Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
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https://hdl.handle.net/10216/154169Direct OA link when available
- Concepts
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Ductus venosus, Medicine, Trisomy, Fetus, Agenesis, Pregnancy, Pediatrics, Obstetrics, Surgery, Biology, GeneticsTop concepts (fields/topics) attached by OpenAlex
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30Total citation count in OpenAlex
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2025: 4, 2024: 6, 2023: 8, 2022: 3, 2021: 2Per-year citation counts (last 5 years)
- References (count)
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28Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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