Dynamic microscopic optical coherence tomography to visualize morphological and functional micro-anatomy of the airways Article Swipe
Tabea Kohlfaerber
,
Mario Pieper
,
Michael Münter
,
Cornelia Holzhausen
,
Martin Ahrens
,
Christian Idel
,
KARL L. BRUCHHAGE
,
Anke Leichtle
,
Peter König
,
Gereon Hüttmann
,
Hinnerk Schulz‐Hildebrandt
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.48550/arxiv.2202.07011
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.48550/arxiv.2202.07011
Imaging airway tissue, optical coherence tomography (OCT) provides cross-sectional images of tissue structures, shows cilia movement and mucus secretion, but does not provide sufficient contrast to differentiate individual cells. By using fast sequences of microscopic resolution OCT (mOCT) images, OCT can picture small signal fluctuations (dynamic) OCT and overcomes the lack in contrast caused by speckle noise. In this way, OCT visualizes airway morphology on a cellular level and allows to track the dynamic behavior of immune cells, as well as mucus transport and secretion. Here, we demonstrate that mOCT, by using temporal tissue fluctuation as contrast (dynamic OCT), provides the possibility to study physiological and pathological tissue processes in vivo.
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Metadata
- Type
- preprint
- Language
- en
- Landing Page
- http://arxiv.org/abs/2202.07011
- https://arxiv.org/pdf/2202.07011
- OA Status
- green
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4226377287
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4226377287Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.48550/arxiv.2202.07011Digital Object Identifier
- Title
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Dynamic microscopic optical coherence tomography to visualize morphological and functional micro-anatomy of the airwaysWork title
- Type
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preprintOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-02-14Full publication date if available
- Authors
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Tabea Kohlfaerber, Mario Pieper, Michael Münter, Cornelia Holzhausen, Martin Ahrens, Christian Idel, KARL L. BRUCHHAGE, Anke Leichtle, Peter König, Gereon Hüttmann, Hinnerk Schulz‐HildebrandtList of authors in order
- Landing page
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https://arxiv.org/abs/2202.07011Publisher landing page
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https://arxiv.org/pdf/2202.07011Direct link to full text PDF
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
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https://arxiv.org/pdf/2202.07011Direct OA link when available
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Optical coherence tomography, Mucus, Speckle pattern, Cilium, Mucociliary clearance, Biomedical engineering, Contrast (vision), Anatomy, Computer science, Optics, Biology, Physics, Computer vision, Medicine, Cell biology, Lung, Internal medicine, EcologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- Related works (count)
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10Other works algorithmically related by OpenAlex
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