E-078 Pipeline embolization of proximal middle cerebral artery aneurysms: A multicenter cohort study Article Swipe
David C. Lauzier
,
Brandon Root
,
Yasha Kayan
,
Josser E Delgado Almandoz
,
Joshua W. Osbun
,
Arindam Chatterjee
,
Kayla L Whaley
,
Megan E. Tipps
,
Christopher J. Moran
,
Akash P. Kansagra
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1136/neurintsurg-2021-snis.173
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1136/neurintsurg-2021-snis.173
Introduction/Purpose Flow diversion of aneurysms located in the M1 segment and middle cerebral artery bifurcation with Pipeline embolization device is sometimes performed, but further study is needed to support its regular use in aneurysm treatment. Here, we report measures of safety and efficacy for Pipeline embolization in the proximal middle cerebral artery in a multi-center cohort. Materials and Methods Clinical and angiographic data of eligible patients undergoing Pipeline embolization of aneurysms located in the M1 segment and middle cerebral artery bifurcation were retrospectively obtained from participating centers and assessed for key clinical, angiographic, and cross-sectional imaging outcomes. Additional details were extracted for patients with complications. Results In our multi-center cohort, complete aneurysm occlusion was achieved in 71% (17/24) of treated aneurysms. There were no deaths or disabling strokes, but non-disabling ischemic strokes occurred in 8% (2/24) of patients. For aneurysms in the M1 segment, complete aneurysm occlusion was observed in 75% (12/16) of aneurysms, aneurysm volume reduction was observed in 100% (16/16) of aneurysms, and non-disabling ischemic strokes occurred in 13% (2/16) of patients. An illustrative example of an M1 aneurysm treated with PED is provided in figure 1. For aneurysms at the middle cerebral artery bifurcation, complete aneurysm occlusion was observed in 63% (5/8) of aneurysms, aneurysm volume reduction occurred in 88% (7/8) of aneurysms, and ischemic or hemorrhagic complications occurred in 0% (0/8) of patients. 19% (3/16) of patients that remained asymptomatic in the follow-up period and underwent cross-sectional imaging had clinically silent basal ganglia infarcts identified. Conclusion Pipeline embolization of cerebral aneurysms in the M1 segment and middle cerebral artery bifurcation demonstrated a 71% rate of complete aneurysm occlusion. There were no deaths or disabling strokes, but there was an 8% rate of non-disabling ischemic strokes. Further work is necessary to describe the long-term effects of silent basal ganglia infarcts caused by PED. Disclosures D. Lauzier: None. B. Root: None. Y. Kayan: 2; C; Microvention, Penumbra, Medtronic. J. Delgado Almandoz: 2; C; Medtronic, Microvention. J. Osbun: 2; C; Medtronic, Microvention. A. Chatterjee: None. K. Whaley: None. M. Tipps: None. C. Moran: 2; C; Medtronic, Cerenovus. A. Kansagra: 2; C; Penumbra, Microvention, iSchemaView.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1136/neurintsurg-2021-snis.173
- https://jnis.bmj.com/content/neurintsurg/13/Suppl_1/A107.full.pdf
- OA Status
- gold
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3185933228
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3185933228Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1136/neurintsurg-2021-snis.173Digital Object Identifier
- Title
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E-078 Pipeline embolization of proximal middle cerebral artery aneurysms: A multicenter cohort studyWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2021Year of publication
- Publication date
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2021-07-26Full publication date if available
- Authors
-
David C. Lauzier, Brandon Root, Yasha Kayan, Josser E Delgado Almandoz, Joshua W. Osbun, Arindam Chatterjee, Kayla L Whaley, Megan E. Tipps, Christopher J. Moran, Akash P. KansagraList of authors in order
- Landing page
-
https://doi.org/10.1136/neurintsurg-2021-snis.173Publisher landing page
- PDF URL
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https://jnis.bmj.com/content/neurintsurg/13/Suppl_1/A107.full.pdfDirect link to full text PDF
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-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://jnis.bmj.com/content/neurintsurg/13/Suppl_1/A107.full.pdfDirect OA link when available
- Concepts
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Medicine, Aneurysm, Middle cerebral artery, Embolization, Asymptomatic, Radiology, Occlusion, Cohort, Surgery, Cardiology, Internal medicine, IschemiaTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- Related works (count)
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10Other works algorithmically related by OpenAlex
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