Effect and safety of gemtuzumab ozogamicin for the treatment of patients with acute myeloid leukaemia: a systematic review protocol Article Swipe
Nor Asiah Muhamad
,
Nor Soleha Mohd Dali
,
Aliza Mohd Yacob
,
Mohd Azlan Kassim
,
Noor Aliza Lodz
,
S A W Fadilah
,
Tahir Aris
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1136/bmjopen-2019-032503
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1136/bmjopen-2019-032503
Introduction Acute myeloid leukaemia (AML) is a type of cancer in which the bone marrow makes abnormal myeloblasts (a type of white blood cell), red blood cells or platelets. Gemtuzumab ozogamicin (GO) holds promise as a new agent that also could be efficacious in newly diagnosed AML with acceptable toxicity. This paper describes the design of a protocol to conduct a systematic review of published studies assessing GO for the treatment of AML. Method and analysis We will conduct a systematic review of randomised controlled trials that investigate the effect and safety of GO for the treatment of patients with AML. We will search for any eligible articles from selected electronic databases. We will follow the Preferred Reporting Items for Systematic reviews and Meta-Analysis for study selection and reporting. We will use The Cochrane Handbook for Systematic Reviews of Interventions and Meta-Analysis as guidance to select eligible studies. All data will be extracted using a standardised data extraction form. Ethics and dissemination There was no patient involved in this study, therefore no ethical consideration is needed. The findings of this study will be disseminated in a peer-reviewed journal and any relevant conference presentation. PROSPERO registration number CRD42019123286.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1136/bmjopen-2019-032503
- https://bmjopen.bmj.com/content/bmjopen/10/6/e032503.full.pdf
- OA Status
- gold
- Cited By
- 1
- References
- 31
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3034561278
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3034561278Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1136/bmjopen-2019-032503Digital Object Identifier
- Title
-
Effect and safety of gemtuzumab ozogamicin for the treatment of patients with acute myeloid leukaemia: a systematic review protocolWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2020Year of publication
- Publication date
-
2020-06-01Full publication date if available
- Authors
-
Nor Asiah Muhamad, Nor Soleha Mohd Dali, Aliza Mohd Yacob, Mohd Azlan Kassim, Noor Aliza Lodz, S A W Fadilah, Tahir ArisList of authors in order
- Landing page
-
https://doi.org/10.1136/bmjopen-2019-032503Publisher landing page
- PDF URL
-
https://bmjopen.bmj.com/content/bmjopen/10/6/e032503.full.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://bmjopen.bmj.com/content/bmjopen/10/6/e032503.full.pdfDirect OA link when available
- Concepts
-
Medicine, Gemtuzumab ozogamicin, Protocol (science), Systematic review, Data extraction, Meta-analysis, Intensive care medicine, MEDLINE, Family medicine, Alternative medicine, Internal medicine, Pathology, Political science, CD33, Law, Biology, Stem cell, CD34, GeneticsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
1Total citation count in OpenAlex
- Citations by year (recent)
-
2022: 1Per-year citation counts (last 5 years)
- References (count)
-
31Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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