Effect of Betel (Areca) Nut Chewing on Fractional Exhaled Nitric Oxide: A Pilot Study Article Swipe

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Areca Exhaled nitric oxide Betel Nut Medicine Nitric oxide Dentistry Internal medicine Asthma Spirometry Structural engineering Engineering

Yi-Chieh Kuo , Francis Fu-Sheng Wu , Ying-Chung Lee , Theodore R. Lin , Julian Crane , Robert Siebers ·

YOU? · · 2018 · Open Access · · DOI: https://doi.org/10.15171/ijoem.2018.1334 · OA: W2896625201

Betel (areca) nuts are extensively chewed in many countries. This has been associated with respiratory symptoms. We aimed to determine whether betel nut chewing is associated with acute changes in fractional exhaled nitric oxide, a non-invasive marker of airway inflammation. Betel nut chewing resulted in an immediate significant decline in fractional exhaled nitric oxide levels that persisted for up to 180 minutes. This effect has to be taken into account in epidemiological studies, reference ranges, and patient preparation.