Effect of Calorie Restriction and Exercise on Type 2 Diabetes Article Swipe
Hira Shakoor
,
Vasso Apostolopoulos
,
Jack Feehan
,
Habiba I. Ali
,
Leila Cheikh Ismail
,
Ayesha Salem Obaid S. Al Dhaheri
,
Lily Stojanovska
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.2478/prilozi-2021-0010
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.2478/prilozi-2021-0010
Type-2 diabetes (T2D) is a chronic condition, generally regarded as an irreversible, that is among the top 10 causes of death globally. The hallmark of T2D is hyperglycemia, which results from disturbances in insulin sensitivity, insulin secretion, β-cell dysfunction and insulin resistance. Several clinical and lifestyle factors are involved in the progression of T2D, such as obesity and physical inactivity. A high-calorie diet is the main contributor to the development of obesity, which results in T2D, as obesity or increased intra-abdominal adipose tissue is related to insulin resistance. Technological advances have contributed to individuals having a more sedentary lifestyle, leading to obesity and T2D. T2D can be treated with lifestyle interventions, such as diet and exercise. Herein, we highlight the positive impact of a very low-calorie diet (VLCD) and lifestyle modalities in the treatment and prevention of T2D. An inclusion of VLCD 400-800 kcal/day for 8 weeks and ≥ 150 minutes exercise 5 times a week as lifestyle interventions can decrease glucose levels to normal, reduce HbA1c and improve insulin resistance and sensitivity. Therefore, a potential mechanism in maintaining glucose homeostasis and remission of T2D by VLCD and exercise reduces body weight.
Related Topics
Concepts
Medicine
Type 2 diabetes
Insulin resistance
Very low calorie diet
Obesity
Calorie restriction
Internal medicine
Weight loss
Endocrinology
Diabetes mellitus
Abdominal obesity
Insulin
Adipose tissue
Sedentary lifestyle
Metabolic syndrome
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.2478/prilozi-2021-0010
- https://sciendo.com/pdf/10.2478/prilozi-2021-0010
- OA Status
- diamond
- Cited By
- 21
- References
- 120
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3159447334
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3159447334Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.2478/prilozi-2021-0010Digital Object Identifier
- Title
-
Effect of Calorie Restriction and Exercise on Type 2 DiabetesWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2021Year of publication
- Publication date
-
2021-04-01Full publication date if available
- Authors
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Hira Shakoor, Vasso Apostolopoulos, Jack Feehan, Habiba I. Ali, Leila Cheikh Ismail, Ayesha Salem Obaid S. Al Dhaheri, Lily StojanovskaList of authors in order
- Landing page
-
https://doi.org/10.2478/prilozi-2021-0010Publisher landing page
- PDF URL
-
https://sciendo.com/pdf/10.2478/prilozi-2021-0010Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
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https://sciendo.com/pdf/10.2478/prilozi-2021-0010Direct OA link when available
- Concepts
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Medicine, Type 2 diabetes, Insulin resistance, Very low calorie diet, Obesity, Calorie restriction, Internal medicine, Weight loss, Endocrinology, Diabetes mellitus, Abdominal obesity, Insulin, Adipose tissue, Sedentary lifestyle, Metabolic syndromeTop concepts (fields/topics) attached by OpenAlex
- Cited by
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21Total citation count in OpenAlex
- Citations by year (recent)
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2025: 5, 2024: 7, 2023: 6, 2022: 1, 2021: 2Per-year citation counts (last 5 years)
- References (count)
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120Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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