Effect of Hydroalcholic Extract 0f Trachyspermum Copticum on Anxiety in Male Rats Article Swipe
Anxiety is a common disorder of unknown origin associated with an unpleasant feeling .According to the anxiolytic effects Trachyspermum Copticum traditional medicine , trachyspermum Copticum effect on anxiety male Wistar rats were investigated. trachyspermum. copticum seed after detection by the University Herbarium, hydro-alcoholic extract was extracted by Soxhlet and the extract powder was prepared using smart legitimate. In this study, male Wistar rats (230 ± 20 g) were placed In groups intact, recipient of the DMSO (solvent extraction) (0.3 cc), received obtained in different doses of 50, 25, 15 mg/kg. All injections were performed intraperitoneally. Half an hour after injection, anxiety was measured using the elevated plus maze. Indicators of anxiety for 5 minutes, including time spent and number of entries into the open arm was recorded. Data were analyzed by ANOVA statistical tests and Tukey test (p <0.05) .The results showed that the group receiving the extract solvent (DMSO) compared to intact in time spent and number of entries into the open arm does not show a significant difference. The group receiving a dose 15 mg/kg compared to the group receiving DMSO in time spent and number of entries into the open arm showed a significant increase. C. copticum hydro-alcoholic extract anxiolytic effects in low doses.
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Metadata
- Type
- article
- Language
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- Landing Page
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- OA Status
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- 10
- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4390132099Canonical identifier for this work in OpenAlex
- Title
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Effect of Hydroalcholic Extract 0f Trachyspermum Copticum on Anxiety in Male RatsWork title
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articleOpenAlex work type
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enPrimary language
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2018Year of publication
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2018-02-01Full publication date if available
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Zohreh Mohammadi manesh, Nasrin Heidarieh, Mohammad Moghadami radList of authors in order
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https://doaj.org/article/72dd1e028a64493eac66634e539b9175Publisher landing page
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
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https://doaj.org/article/72dd1e028a64493eac66634e539b9175Direct OA link when available
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Traditional medicine, MedicineTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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