Effect of Reconstituted Human Apolipoprotein A-I on Recurrent Ischemic Events in Survivors of Acute MI Article Swipe
Thomas J. Povsic
,
Serge Korjian
,
M. Cecilia Bahit
,
Gerald Chi
,
Danielle Duffy
,
John H. Alexander
,
Dragoș Vinereanu
,
Pierluigi Tricoci
,
Sojaita Jenny Mears
,
Lawrence I. Deckelbaum
,
Marc P. Bonaca
,
Paul M. Ridker
,
Shaun G. Goodman
,
Jan H. Cornel
,
Basil S. Lewis
,
Alexander Parkhomenko
,
Renato D. Lópes
,
Philip E. Aylward
,
A. Michael Lincoff
,
Mark Heise
,
Frank M. Sacks
,
José Carlos Nicolau
,
Béla Merkely
,
Jarosław Trębacz
,
Peter Libby
,
Stephen J. Nicholls
,
Stuart Pocock
,
Deepak L. Bhatt
,
John J.P. Kastelein
,
Christoph Bode
,
Kenneth W. Mahaffey
,
Philippe Gabríel Steg
,
Michał Tendera
,
Kevin R. Bainey
,
Robert A. Harrington
,
Roxana Mehran
,
Daniel Duerschmied
,
Bronwyn A. Kingwell
,
C. Michael Gibson
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1016/j.jacc.2024.03.396
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1016/j.jacc.2024.03.396
Although CSL112 did not significantly reduce the occurrence of the primary study endpoints, patients treated with CSL112 infusions had numerically lower rates of CV death and MI, type-1 MI, and stent thrombosis-related MI compared with placebo. These findings could suggest a role of apoA-I in reducing subsequent plaque disruption events via enhanced cholesterol efflux. Further prospective data would be needed to confirm these observations.
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Metadata
- Type
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- Language
- en
- Landing Page
- https://doi.org/10.1016/j.jacc.2024.03.396
- OA Status
- hybrid
- Cited By
- 21
- References
- 48
- Related Works
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- OpenAlex ID
- https://openalex.org/W4394014650
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4394014650Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1016/j.jacc.2024.03.396Digital Object Identifier
- Title
-
Effect of Reconstituted Human Apolipoprotein A-I on Recurrent Ischemic Events in Survivors of Acute MIWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
-
2024-04-06Full publication date if available
- Authors
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Thomas J. Povsic, Serge Korjian, M. Cecilia Bahit, Gerald Chi, Danielle Duffy, John H. Alexander, Dragoș Vinereanu, Pierluigi Tricoci, Sojaita Jenny Mears, Lawrence I. Deckelbaum, Marc P. Bonaca, Paul M. Ridker, Shaun G. Goodman, Jan H. Cornel, Basil S. Lewis, Alexander Parkhomenko, Renato D. Lópes, Philip E. Aylward, A. Michael Lincoff, Mark Heise, Frank M. Sacks, José Carlos Nicolau, Béla Merkely, Jarosław Trębacz, Peter Libby, Stephen J. Nicholls, Stuart Pocock, Deepak L. Bhatt, John J.P. Kastelein, Christoph Bode, Kenneth W. Mahaffey, Philippe Gabríel Steg, Michał Tendera, Kevin R. Bainey, Robert A. Harrington, Roxana Mehran, Daniel Duerschmied, Bronwyn A. Kingwell, C. Michael GibsonList of authors in order
- Landing page
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https://doi.org/10.1016/j.jacc.2024.03.396Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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hybridOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1016/j.jacc.2024.03.396Direct OA link when available
- Concepts
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Medicine, Internal medicine, Myocardial infarction, Placebo, Incidence (geometry), Randomized controlled trial, Gastroenterology, Clinical endpoint, Surgery, Cardiology, Pathology, Optics, Alternative medicine, PhysicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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21Total citation count in OpenAlex
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2025: 8, 2024: 13Per-year citation counts (last 5 years)
- References (count)
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48Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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