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EPJ Web of Conferences • Vol 140
Effect of the particle shape on the particle dynamics in a spheronization process
January 2017 • Dominik Weis, Maria Niesing, Markus Thommes, Sergiy Antonyuk
Spherical granules with a narrow size distribution are widely used in many pharmaceutical applications. Extrusion-spheronization is a well-established process to produce such pharmaceutical pellets. The cylindrical extrudates from the extrusion step are rounded in the spheronizer. The formation mechanisms inside of a spheronizer depend strongly on the particle dynamics. To describe the complex particle flow and interactions, the Discrete Element Method can be used. In our previous works the spherical particles dur…
Extrusion
Materials Science
Process (Computing)
Composite Material
Physics
Computer Science
Oceanography