Effects of Alterations of Post-Mortem Delay and Other Tissue-Collection Variables on Metabolite Levels in Human and Rat Brain Article Swipe
Melissa Scholefield
,
Stephanie J. Church
,
Jingshu Xu
,
Andrew Robinson
,
Natalie J. Gardiner
,
Federico Roncaroli
,
Nigel M. Hooper
,
Richard D. Unwin
,
Garth J. S. Cooper
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.3390/metabo10110438
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.3390/metabo10110438
The use of post-mortem human tissue is indispensable in studies investigating alterations in metabolite levels in neurodegenerative conditions such as Alzheimer’s disease (AD). However, variability between samples may have unknown effects on metabolite concentrations. The aim of this study was to characterize the impact of such variables. Cingulate gyrus was obtained from AD cases and controls, from three brain banks. Gas chromatography-mass spectrometry (GC-MS) was used to measure and compare the levels of 66 identifiable metabolites in these tissues to determine effects of tissue-collection variables. The effect of PMD was further investigated by analysis of rat brain cortex and cerebellum collected following post-mortem delays (PMDs) of zero to 72 h. Metabolite levels between cases and controls were not replicable across cohorts with variable age- and gender-matching, PMD, and control Braak staging. Analysis of rat tissues found significant effects of PMD on 31 of 63 identified metabolites over periods up to 72 h. PMD must be kept under 24 h for metabolomics analyses on brain tissues to yield replicable results. Tissues should also be well age- and gender-matched, and Braak stage in controls should be kept to a minimum in order to minimize the impact of these variables in influencing metabolite variability.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/metabo10110438
- https://www.mdpi.com/2218-1989/10/11/438/pdf?version=1604029342
- OA Status
- gold
- Cited By
- 20
- References
- 26
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3097066069
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3097066069Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/metabo10110438Digital Object Identifier
- Title
-
Effects of Alterations of Post-Mortem Delay and Other Tissue-Collection Variables on Metabolite Levels in Human and Rat BrainWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2020Year of publication
- Publication date
-
2020-10-29Full publication date if available
- Authors
-
Melissa Scholefield, Stephanie J. Church, Jingshu Xu, Andrew Robinson, Natalie J. Gardiner, Federico Roncaroli, Nigel M. Hooper, Richard D. Unwin, Garth J. S. CooperList of authors in order
- Landing page
-
https://doi.org/10.3390/metabo10110438Publisher landing page
- PDF URL
-
https://www.mdpi.com/2218-1989/10/11/438/pdf?version=1604029342Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.mdpi.com/2218-1989/10/11/438/pdf?version=1604029342Direct OA link when available
- Concepts
-
Metabolite, Human brain, Chemistry, Neuroscience, Physiology, Medicine, Biology, Internal medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
20Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 2, 2024: 5, 2023: 6, 2022: 3, 2021: 4Per-year citation counts (last 5 years)
- References (count)
-
26Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3097066069 |
|---|---|
| doi | https://doi.org/10.3390/metabo10110438 |
| ids.doi | https://doi.org/10.3390/metabo10110438 |
| ids.mag | 3097066069 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/33138273 |
| ids.openalex | https://openalex.org/W3097066069 |
| fwci | 1.26785065 |
| type | article |
| title | Effects of Alterations of Post-Mortem Delay and Other Tissue-Collection Variables on Metabolite Levels in Human and Rat Brain |
| awards[0].id | https://openalex.org/G8321522423 |
| awards[0].funder_id | https://openalex.org/F4320321983 |
| awards[0].display_name | |
| awards[0].funder_award_id | UOAX0815 |
| awards[0].funder_display_name | Ministry of Business, Innovation and Employment |
| awards[1].id | https://openalex.org/G1367756817 |
| awards[1].funder_id | https://openalex.org/F4320330646 |
| awards[1].display_name | |
| awards[1].funder_award_id | N/A |
| awards[1].funder_display_name | Greater Manchester Comprehensive Local Research Network |
| awards[2].id | https://openalex.org/G8055047137 |
| awards[2].funder_id | https://openalex.org/F4320320782 |
| awards[2].display_name | |
| awards[2].funder_award_id | 3627036 |
| awards[2].funder_display_name | Maurice and Phyllis Paykel Trust |
| awards[3].id | https://openalex.org/G1122611660 |
| awards[3].funder_id | https://openalex.org/F4320334626 |
| awards[3].display_name | |
| awards[3].funder_award_id | MR/L010445/1; MR/L011093/1 |
| awards[3].funder_display_name | Medical Research Council |
| awards[4].id | https://openalex.org/G1290449032 |
| awards[4].funder_id | https://openalex.org/F4320320807 |
| awards[4].display_name | |
| awards[4].funder_award_id | N/A |
| awards[4].funder_display_name | Neurological Foundation of New Zealand |
| awards[5].id | https://openalex.org/G6306281203 |
| awards[5].funder_id | https://openalex.org/F4320330087 |
| awards[5].display_name | |
| awards[5].funder_award_id | 9341-3622506 |
| awards[5].funder_display_name | Maurice Wilkins Centre for Molecular Biodiscovery |
| awards[6].id | https://openalex.org/G856637828 |
| awards[6].funder_id | https://openalex.org/F4320313769 |
| awards[6].display_name | |
| awards[6].funder_award_id | 3456030; 3627092; 3701339; 3703253; 3702870 |
| awards[6].funder_display_name | Oakley Mental Health Research Foundation |
| biblio.issue | 11 |
| biblio.volume | 10 |
| biblio.last_page | 438 |
| biblio.first_page | 438 |
| topics[0].id | https://openalex.org/T10836 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9995999932289124 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1312 |
| topics[0].subfield.display_name | Molecular Biology |
| topics[0].display_name | Metabolomics and Mass Spectrometry Studies |
| topics[1].id | https://openalex.org/T11337 |
| topics[1].field.id | https://openalex.org/fields/28 |
| topics[1].field.display_name | Neuroscience |
| topics[1].score | 0.9908999800682068 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2803 |
| topics[1].subfield.display_name | Biological Psychiatry |
| topics[1].display_name | Tryptophan and brain disorders |
| topics[2].id | https://openalex.org/T12267 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9839000105857849 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2737 |
| topics[2].subfield.display_name | Physiology |
| topics[2].display_name | Diet and metabolism studies |
| funders[0].id | https://openalex.org/F4320313769 |
| funders[0].ror | |
| funders[0].display_name | Oakley Mental Health Research Foundation |
| funders[1].id | https://openalex.org/F4320320782 |
| funders[1].ror | https://ror.org/05tx9pa51 |
| funders[1].display_name | Maurice and Phyllis Paykel Trust |
| funders[2].id | https://openalex.org/F4320320807 |
| funders[2].ror | https://ror.org/01jjkzv49 |
| funders[2].display_name | Neurological Foundation of New Zealand |
| funders[3].id | https://openalex.org/F4320321983 |
| funders[3].ror | https://ror.org/02jtq1b51 |
| funders[3].display_name | Ministry of Business, Innovation and Employment |
| funders[4].id | https://openalex.org/F4320330087 |
| funders[4].ror | https://ror.org/0327mmx61 |
| funders[4].display_name | Maurice Wilkins Centre for Molecular Biodiscovery |
| funders[5].id | https://openalex.org/F4320330646 |
| funders[5].ror | |
| funders[5].display_name | Greater Manchester Comprehensive Local Research Network |
| funders[6].id | https://openalex.org/F4320334626 |
| funders[6].ror | https://ror.org/03x94j517 |
| funders[6].display_name | Medical Research Council |
| is_xpac | False |
| apc_list.value | 2000 |
| apc_list.currency | CHF |
| apc_list.value_usd | 2165 |
| apc_paid.value | 2000 |
| apc_paid.currency | CHF |
| apc_paid.value_usd | 2165 |
| concepts[0].id | https://openalex.org/C2777477808 |
| concepts[0].level | 2 |
| concepts[0].score | 0.8147368431091309 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q407595 |
| concepts[0].display_name | Metabolite |
| concepts[1].id | https://openalex.org/C2777670902 |
| concepts[1].level | 2 |
| concepts[1].score | 0.424820214509964 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q492038 |
| concepts[1].display_name | Human brain |
| concepts[2].id | https://openalex.org/C185592680 |
| concepts[2].level | 0 |
| concepts[2].score | 0.3639804422855377 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[2].display_name | Chemistry |
| concepts[3].id | https://openalex.org/C169760540 |
| concepts[3].level | 1 |
| concepts[3].score | 0.3486115634441376 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q207011 |
| concepts[3].display_name | Neuroscience |
| concepts[4].id | https://openalex.org/C42407357 |
| concepts[4].level | 1 |
| concepts[4].score | 0.3462918996810913 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q521 |
| concepts[4].display_name | Physiology |
| concepts[5].id | https://openalex.org/C71924100 |
| concepts[5].level | 0 |
| concepts[5].score | 0.3436765968799591 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[5].display_name | Medicine |
| concepts[6].id | https://openalex.org/C86803240 |
| concepts[6].level | 0 |
| concepts[6].score | 0.3402918577194214 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[6].display_name | Biology |
| concepts[7].id | https://openalex.org/C126322002 |
| concepts[7].level | 1 |
| concepts[7].score | 0.33910995721817017 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[7].display_name | Internal medicine |
| keywords[0].id | https://openalex.org/keywords/metabolite |
| keywords[0].score | 0.8147368431091309 |
| keywords[0].display_name | Metabolite |
| keywords[1].id | https://openalex.org/keywords/human-brain |
| keywords[1].score | 0.424820214509964 |
| keywords[1].display_name | Human brain |
| keywords[2].id | https://openalex.org/keywords/chemistry |
| keywords[2].score | 0.3639804422855377 |
| keywords[2].display_name | Chemistry |
| keywords[3].id | https://openalex.org/keywords/neuroscience |
| keywords[3].score | 0.3486115634441376 |
| keywords[3].display_name | Neuroscience |
| keywords[4].id | https://openalex.org/keywords/physiology |
| keywords[4].score | 0.3462918996810913 |
| keywords[4].display_name | Physiology |
| keywords[5].id | https://openalex.org/keywords/medicine |
| keywords[5].score | 0.3436765968799591 |
| keywords[5].display_name | Medicine |
| keywords[6].id | https://openalex.org/keywords/biology |
| keywords[6].score | 0.3402918577194214 |
| keywords[6].display_name | Biology |
| keywords[7].id | https://openalex.org/keywords/internal-medicine |
| keywords[7].score | 0.33910995721817017 |
| keywords[7].display_name | Internal medicine |
| language | en |
| locations[0].id | doi:10.3390/metabo10110438 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2764402194 |
| locations[0].source.issn | 2218-1989 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2218-1989 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Metabolites |
| locations[0].source.host_organization | https://openalex.org/P4310310987 |
| locations[0].source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310310987 |
| locations[0].source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.mdpi.com/2218-1989/10/11/438/pdf?version=1604029342 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Metabolites |
| locations[0].landing_page_url | https://doi.org/10.3390/metabo10110438 |
| locations[1].id | pmid:33138273 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Metabolites |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/33138273 |
| locations[2].id | pmh:oai:doaj.org/article:bd6bf168e484432ab371cc420f223056 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].license | cc-by-sa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | https://openalex.org/licenses/cc-by-sa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Metabolites, Vol 10, Iss 11, p 438 (2020) |
| locations[2].landing_page_url | https://doaj.org/article/bd6bf168e484432ab371cc420f223056 |
| locations[3].id | pmh:oai:mdpi.com:/2218-1989/10/11/438/ |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S4306400947 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | True |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | MDPI (MDPI AG) |
| locations[3].source.host_organization | https://openalex.org/I4210097602 |
| locations[3].source.host_organization_name | Multidisciplinary Digital Publishing Institute (Switzerland) |
| locations[3].source.host_organization_lineage | https://openalex.org/I4210097602 |
| locations[3].license | cc-by |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | https://openalex.org/licenses/cc-by |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Metabolites; Volume 10; Issue 11; Pages: 438 |
| locations[3].landing_page_url | https://dx.doi.org/10.3390/metabo10110438 |
| locations[4].id | pmh:oai:pubmedcentral.nih.gov:7694048 |
| locations[4].is_oa | True |
| locations[4].source.id | https://openalex.org/S2764455111 |
| locations[4].source.issn | |
| locations[4].source.type | repository |
| locations[4].source.is_oa | False |
| locations[4].source.issn_l | |
| locations[4].source.is_core | False |
| locations[4].source.is_in_doaj | False |
| locations[4].source.display_name | PubMed Central |
| locations[4].source.host_organization | https://openalex.org/I1299303238 |
| locations[4].source.host_organization_name | National Institutes of Health |
| locations[4].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[4].license | other-oa |
| locations[4].pdf_url | |
| locations[4].version | submittedVersion |
| locations[4].raw_type | Text |
| locations[4].license_id | https://openalex.org/licenses/other-oa |
| locations[4].is_accepted | False |
| locations[4].is_published | False |
| locations[4].raw_source_name | Metabolites |
| locations[4].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/7694048 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5029480517 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-6810-0986 |
| authorships[0].author.display_name | Melissa Scholefield |
| authorships[0].countries | GB |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I2799725268, https://openalex.org/I28407311 |
| authorships[0].affiliations[0].raw_affiliation_string | Centre for Advanced Discovery & Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK |
| authorships[0].institutions[0].id | https://openalex.org/I2799725268 |
| authorships[0].institutions[0].ror | https://ror.org/04rrkhs81 |
| authorships[0].institutions[0].type | healthcare |
| authorships[0].institutions[0].lineage | https://openalex.org/I2799725268 |
| authorships[0].institutions[0].country_code | GB |
| authorships[0].institutions[0].display_name | Manchester Academic Health Science Centre |
| authorships[0].institutions[1].id | https://openalex.org/I28407311 |
| authorships[0].institutions[1].ror | https://ror.org/027m9bs27 |
| authorships[0].institutions[1].type | education |
| authorships[0].institutions[1].lineage | https://openalex.org/I28407311 |
| authorships[0].institutions[1].country_code | GB |
| authorships[0].institutions[1].display_name | University of Manchester |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Melissa Scholefield |
| authorships[0].is_corresponding | True |
| authorships[0].raw_affiliation_strings | Centre for Advanced Discovery & Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK |
| authorships[1].author.id | https://openalex.org/A5003042649 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-4643-9575 |
| authorships[1].author.display_name | Stephanie J. Church |
| authorships[1].countries | GB |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I2799725268, https://openalex.org/I28407311 |
| authorships[1].affiliations[0].raw_affiliation_string | Centre for Advanced Discovery & Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK |
| authorships[1].institutions[0].id | https://openalex.org/I2799725268 |
| authorships[1].institutions[0].ror | https://ror.org/04rrkhs81 |
| authorships[1].institutions[0].type | healthcare |
| authorships[1].institutions[0].lineage | https://openalex.org/I2799725268 |
| authorships[1].institutions[0].country_code | GB |
| authorships[1].institutions[0].display_name | Manchester Academic Health Science Centre |
| authorships[1].institutions[1].id | https://openalex.org/I28407311 |
| authorships[1].institutions[1].ror | https://ror.org/027m9bs27 |
| authorships[1].institutions[1].type | education |
| authorships[1].institutions[1].lineage | https://openalex.org/I28407311 |
| authorships[1].institutions[1].country_code | GB |
| authorships[1].institutions[1].display_name | University of Manchester |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Stephanie J. Church |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Centre for Advanced Discovery & Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK |
| authorships[2].author.id | https://openalex.org/A5049984637 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-0130-348X |
| authorships[2].author.display_name | Jingshu Xu |
| authorships[2].countries | GB, NZ |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I2799725268, https://openalex.org/I28407311 |
| authorships[2].affiliations[0].raw_affiliation_string | Centre for Advanced Discovery & Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK |
| authorships[2].affiliations[1].institution_ids | https://openalex.org/I154130895 |
| authorships[2].affiliations[1].raw_affiliation_string | School of Biological Sciences, Faculty of Science, University of Auckland, Private Bag 92 019, Auckland 1142, New Zealand |
| authorships[2].institutions[0].id | https://openalex.org/I2799725268 |
| authorships[2].institutions[0].ror | https://ror.org/04rrkhs81 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I2799725268 |
| authorships[2].institutions[0].country_code | GB |
| authorships[2].institutions[0].display_name | Manchester Academic Health Science Centre |
| authorships[2].institutions[1].id | https://openalex.org/I28407311 |
| authorships[2].institutions[1].ror | https://ror.org/027m9bs27 |
| authorships[2].institutions[1].type | education |
| authorships[2].institutions[1].lineage | https://openalex.org/I28407311 |
| authorships[2].institutions[1].country_code | GB |
| authorships[2].institutions[1].display_name | University of Manchester |
| authorships[2].institutions[2].id | https://openalex.org/I154130895 |
| authorships[2].institutions[2].ror | https://ror.org/03b94tp07 |
| authorships[2].institutions[2].type | education |
| authorships[2].institutions[2].lineage | https://openalex.org/I154130895 |
| authorships[2].institutions[2].country_code | NZ |
| authorships[2].institutions[2].display_name | University of Auckland |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Jingshu Xu |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Centre for Advanced Discovery & Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK, School of Biological Sciences, Faculty of Science, University of Auckland, Private Bag 92 019, Auckland 1142, New Zealand |
| authorships[3].author.id | https://openalex.org/A5040415602 |
| authorships[3].author.orcid | https://orcid.org/0000-0003-2208-7728 |
| authorships[3].author.display_name | Andrew Robinson |
| authorships[3].countries | GB |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I28407311, https://openalex.org/I4210111611 |
| authorships[3].affiliations[0].raw_affiliation_string | Division of Neuroscience & Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Salford Royal Hospital, Salford M6 8HD, UK |
| authorships[3].institutions[0].id | https://openalex.org/I4210111611 |
| authorships[3].institutions[0].ror | https://ror.org/027rkpb34 |
| authorships[3].institutions[0].type | healthcare |
| authorships[3].institutions[0].lineage | https://openalex.org/I2801120809, https://openalex.org/I4210111611 |
| authorships[3].institutions[0].country_code | GB |
| authorships[3].institutions[0].display_name | Salford Royal Hospital |
| authorships[3].institutions[1].id | https://openalex.org/I28407311 |
| authorships[3].institutions[1].ror | https://ror.org/027m9bs27 |
| authorships[3].institutions[1].type | education |
| authorships[3].institutions[1].lineage | https://openalex.org/I28407311 |
| authorships[3].institutions[1].country_code | GB |
| authorships[3].institutions[1].display_name | University of Manchester |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Andrew C. Robinson |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Division of Neuroscience & Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Salford Royal Hospital, Salford M6 8HD, UK |
| authorships[4].author.id | https://openalex.org/A5027313903 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-8287-1181 |
| authorships[4].author.display_name | Natalie J. Gardiner |
| authorships[4].countries | GB |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I2799725268, https://openalex.org/I28407311 |
| authorships[4].affiliations[0].raw_affiliation_string | Division of Diabetes, Endocrinology & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Oxford Rd, Manchester M13 9PL, UK |
| authorships[4].institutions[0].id | https://openalex.org/I2799725268 |
| authorships[4].institutions[0].ror | https://ror.org/04rrkhs81 |
| authorships[4].institutions[0].type | healthcare |
| authorships[4].institutions[0].lineage | https://openalex.org/I2799725268 |
| authorships[4].institutions[0].country_code | GB |
| authorships[4].institutions[0].display_name | Manchester Academic Health Science Centre |
| authorships[4].institutions[1].id | https://openalex.org/I28407311 |
| authorships[4].institutions[1].ror | https://ror.org/027m9bs27 |
| authorships[4].institutions[1].type | education |
| authorships[4].institutions[1].lineage | https://openalex.org/I28407311 |
| authorships[4].institutions[1].country_code | GB |
| authorships[4].institutions[1].display_name | University of Manchester |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Natalie J. Gardiner |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Division of Diabetes, Endocrinology & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Oxford Rd, Manchester M13 9PL, UK |
| authorships[5].author.id | https://openalex.org/A5066934299 |
| authorships[5].author.orcid | https://orcid.org/0000-0003-3650-5572 |
| authorships[5].author.display_name | Federico Roncaroli |
| authorships[5].countries | GB |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I2799725268, https://openalex.org/I28407311 |
| authorships[5].affiliations[0].raw_affiliation_string | Division of Neuroscience & Experimental Psychology, and Lydia Becker Institute of Immunology & Inflammation, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK |
| authorships[5].institutions[0].id | https://openalex.org/I2799725268 |
| authorships[5].institutions[0].ror | https://ror.org/04rrkhs81 |
| authorships[5].institutions[0].type | healthcare |
| authorships[5].institutions[0].lineage | https://openalex.org/I2799725268 |
| authorships[5].institutions[0].country_code | GB |
| authorships[5].institutions[0].display_name | Manchester Academic Health Science Centre |
| authorships[5].institutions[1].id | https://openalex.org/I28407311 |
| authorships[5].institutions[1].ror | https://ror.org/027m9bs27 |
| authorships[5].institutions[1].type | education |
| authorships[5].institutions[1].lineage | https://openalex.org/I28407311 |
| authorships[5].institutions[1].country_code | GB |
| authorships[5].institutions[1].display_name | University of Manchester |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Federico Roncaroli |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Division of Neuroscience & Experimental Psychology, and Lydia Becker Institute of Immunology & Inflammation, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK |
| authorships[6].author.id | https://openalex.org/A5042797848 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-5811-3484 |
| authorships[6].author.display_name | Nigel M. Hooper |
| authorships[6].countries | GB |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I2799725268, https://openalex.org/I28407311 |
| authorships[6].affiliations[0].raw_affiliation_string | Division of Neuroscience & Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK |
| authorships[6].institutions[0].id | https://openalex.org/I2799725268 |
| authorships[6].institutions[0].ror | https://ror.org/04rrkhs81 |
| authorships[6].institutions[0].type | healthcare |
| authorships[6].institutions[0].lineage | https://openalex.org/I2799725268 |
| authorships[6].institutions[0].country_code | GB |
| authorships[6].institutions[0].display_name | Manchester Academic Health Science Centre |
| authorships[6].institutions[1].id | https://openalex.org/I28407311 |
| authorships[6].institutions[1].ror | https://ror.org/027m9bs27 |
| authorships[6].institutions[1].type | education |
| authorships[6].institutions[1].lineage | https://openalex.org/I28407311 |
| authorships[6].institutions[1].country_code | GB |
| authorships[6].institutions[1].display_name | University of Manchester |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Nigel M. Hooper |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Division of Neuroscience & Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK |
| authorships[7].author.id | https://openalex.org/A5022672574 |
| authorships[7].author.orcid | https://orcid.org/0000-0001-7955-9111 |
| authorships[7].author.display_name | Richard D. Unwin |
| authorships[7].countries | GB |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I2799725268, https://openalex.org/I28407311 |
| authorships[7].affiliations[0].raw_affiliation_string | Centre for Advanced Discovery & Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK |
| authorships[7].affiliations[1].institution_ids | https://openalex.org/I28407311 |
| authorships[7].affiliations[1].raw_affiliation_string | Stoller Biomarker Discovery Centre & Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Citylabs 1.0 (Third Floor), Nelson Street, Manchester M13 9NQ, UK |
| authorships[7].institutions[0].id | https://openalex.org/I2799725268 |
| authorships[7].institutions[0].ror | https://ror.org/04rrkhs81 |
| authorships[7].institutions[0].type | healthcare |
| authorships[7].institutions[0].lineage | https://openalex.org/I2799725268 |
| authorships[7].institutions[0].country_code | GB |
| authorships[7].institutions[0].display_name | Manchester Academic Health Science Centre |
| authorships[7].institutions[1].id | https://openalex.org/I28407311 |
| authorships[7].institutions[1].ror | https://ror.org/027m9bs27 |
| authorships[7].institutions[1].type | education |
| authorships[7].institutions[1].lineage | https://openalex.org/I28407311 |
| authorships[7].institutions[1].country_code | GB |
| authorships[7].institutions[1].display_name | University of Manchester |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Richard D. Unwin |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Centre for Advanced Discovery & Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK, Stoller Biomarker Discovery Centre & Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Citylabs 1.0 (Third Floor), Nelson Street, Manchester M13 9NQ, UK |
| authorships[8].author.id | https://openalex.org/A5007013563 |
| authorships[8].author.orcid | https://orcid.org/0000-0001-5241-3163 |
| authorships[8].author.display_name | Garth J. S. Cooper |
| authorships[8].countries | GB, NZ |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I2799725268, https://openalex.org/I28407311 |
| authorships[8].affiliations[0].raw_affiliation_string | Centre for Advanced Discovery & Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK |
| authorships[8].affiliations[1].institution_ids | https://openalex.org/I154130895 |
| authorships[8].affiliations[1].raw_affiliation_string | School of Biological Sciences, Faculty of Science, University of Auckland, Private Bag 92 019, Auckland 1142, New Zealand |
| authorships[8].institutions[0].id | https://openalex.org/I2799725268 |
| authorships[8].institutions[0].ror | https://ror.org/04rrkhs81 |
| authorships[8].institutions[0].type | healthcare |
| authorships[8].institutions[0].lineage | https://openalex.org/I2799725268 |
| authorships[8].institutions[0].country_code | GB |
| authorships[8].institutions[0].display_name | Manchester Academic Health Science Centre |
| authorships[8].institutions[1].id | https://openalex.org/I28407311 |
| authorships[8].institutions[1].ror | https://ror.org/027m9bs27 |
| authorships[8].institutions[1].type | education |
| authorships[8].institutions[1].lineage | https://openalex.org/I28407311 |
| authorships[8].institutions[1].country_code | GB |
| authorships[8].institutions[1].display_name | University of Manchester |
| authorships[8].institutions[2].id | https://openalex.org/I154130895 |
| authorships[8].institutions[2].ror | https://ror.org/03b94tp07 |
| authorships[8].institutions[2].type | education |
| authorships[8].institutions[2].lineage | https://openalex.org/I154130895 |
| authorships[8].institutions[2].country_code | NZ |
| authorships[8].institutions[2].display_name | University of Auckland |
| authorships[8].author_position | last |
| authorships[8].raw_author_name | Garth J. S. Cooper |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Centre for Advanced Discovery & Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester M19 9NT, UK, School of Biological Sciences, Faculty of Science, University of Auckland, Private Bag 92 019, Auckland 1142, New Zealand |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.mdpi.com/2218-1989/10/11/438/pdf?version=1604029342 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Effects of Alterations of Post-Mortem Delay and Other Tissue-Collection Variables on Metabolite Levels in Human and Rat Brain |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-08T23:21:52.890332 |
| primary_topic.id | https://openalex.org/T10836 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9995999932289124 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1312 |
| primary_topic.subfield.display_name | Molecular Biology |
| primary_topic.display_name | Metabolomics and Mass Spectrometry Studies |
| related_works | https://openalex.org/W2521903434, https://openalex.org/W1753739957, https://openalex.org/W2085913165, https://openalex.org/W2011282322, https://openalex.org/W2024044986, https://openalex.org/W2005550771, https://openalex.org/W323632276, https://openalex.org/W2418404479, https://openalex.org/W2078089453, https://openalex.org/W2007751088 |
| cited_by_count | 20 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 2 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 5 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 6 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 3 |
| counts_by_year[4].year | 2021 |
| counts_by_year[4].cited_by_count | 4 |
| locations_count | 5 |
| best_oa_location.id | doi:10.3390/metabo10110438 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2764402194 |
| best_oa_location.source.issn | 2218-1989 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2218-1989 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Metabolites |
| best_oa_location.source.host_organization | https://openalex.org/P4310310987 |
| best_oa_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| best_oa_location.source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.mdpi.com/2218-1989/10/11/438/pdf?version=1604029342 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Metabolites |
| best_oa_location.landing_page_url | https://doi.org/10.3390/metabo10110438 |
| primary_location.id | doi:10.3390/metabo10110438 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2764402194 |
| primary_location.source.issn | 2218-1989 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2218-1989 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Metabolites |
| primary_location.source.host_organization | https://openalex.org/P4310310987 |
| primary_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| primary_location.source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.mdpi.com/2218-1989/10/11/438/pdf?version=1604029342 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Metabolites |
| primary_location.landing_page_url | https://doi.org/10.3390/metabo10110438 |
| publication_date | 2020-10-29 |
| publication_year | 2020 |
| referenced_works | https://openalex.org/W3019212916, https://openalex.org/W2295054364, https://openalex.org/W2166025745, https://openalex.org/W2906903840, https://openalex.org/W2093057630, https://openalex.org/W1963830115, https://openalex.org/W2004824110, https://openalex.org/W2148650719, https://openalex.org/W2007137549, https://openalex.org/W2793039731, https://openalex.org/W2519085183, https://openalex.org/W2594071266, https://openalex.org/W2087657802, https://openalex.org/W2414892106, https://openalex.org/W2094198213, https://openalex.org/W2090949801, https://openalex.org/W2765164306, https://openalex.org/W2009487160, https://openalex.org/W2031155126, https://openalex.org/W3048984721, https://openalex.org/W3001746381, https://openalex.org/W2137919354, https://openalex.org/W2103597171, https://openalex.org/W2418667749, https://openalex.org/W1840108306, https://openalex.org/W1611854178 |
| referenced_works_count | 26 |
| abstract_inverted_index.a | 186 |
| abstract_inverted_index.h | 158 |
| abstract_inverted_index.24 | 157 |
| abstract_inverted_index.31 | 141 |
| abstract_inverted_index.63 | 143 |
| abstract_inverted_index.66 | 73 |
| abstract_inverted_index.72 | 108, 150 |
| abstract_inverted_index.AD | 52 |
| abstract_inverted_index.as | 19 |
| abstract_inverted_index.be | 154, 172, 183 |
| abstract_inverted_index.by | 92 |
| abstract_inverted_index.h. | 109, 151 |
| abstract_inverted_index.in | 8, 12, 15, 76, 180, 188, 197 |
| abstract_inverted_index.is | 6 |
| abstract_inverted_index.of | 2, 36, 44, 72, 82, 87, 94, 105, 132, 138, 142, 194 |
| abstract_inverted_index.on | 31, 140, 162 |
| abstract_inverted_index.to | 40, 66, 79, 107, 149, 165, 185, 190 |
| abstract_inverted_index.up | 148 |
| abstract_inverted_index.Gas | 60 |
| abstract_inverted_index.PMD | 88, 139, 152 |
| abstract_inverted_index.The | 0, 34, 85 |
| abstract_inverted_index.aim | 35 |
| abstract_inverted_index.and | 54, 68, 98, 114, 124, 127, 175, 177 |
| abstract_inverted_index.for | 159 |
| abstract_inverted_index.may | 27 |
| abstract_inverted_index.not | 117 |
| abstract_inverted_index.rat | 95, 133 |
| abstract_inverted_index.the | 42, 70, 192 |
| abstract_inverted_index.use | 1 |
| abstract_inverted_index.was | 39, 49, 64, 89 |
| abstract_inverted_index.PMD, | 126 |
| abstract_inverted_index.age- | 123, 174 |
| abstract_inverted_index.also | 171 |
| abstract_inverted_index.from | 51, 56 |
| abstract_inverted_index.have | 28 |
| abstract_inverted_index.kept | 155, 184 |
| abstract_inverted_index.must | 153 |
| abstract_inverted_index.over | 146 |
| abstract_inverted_index.such | 18, 45 |
| abstract_inverted_index.this | 37 |
| abstract_inverted_index.used | 65 |
| abstract_inverted_index.well | 173 |
| abstract_inverted_index.were | 116 |
| abstract_inverted_index.with | 121 |
| abstract_inverted_index.zero | 106 |
| abstract_inverted_index.(AD). | 22 |
| abstract_inverted_index.Braak | 129, 178 |
| abstract_inverted_index.brain | 58, 96, 163 |
| abstract_inverted_index.cases | 53, 113 |
| abstract_inverted_index.found | 135 |
| abstract_inverted_index.gyrus | 48 |
| abstract_inverted_index.human | 4 |
| abstract_inverted_index.order | 189 |
| abstract_inverted_index.stage | 179 |
| abstract_inverted_index.study | 38 |
| abstract_inverted_index.these | 77, 195 |
| abstract_inverted_index.three | 57 |
| abstract_inverted_index.under | 156 |
| abstract_inverted_index.yield | 166 |
| abstract_inverted_index.(PMDs) | 104 |
| abstract_inverted_index.across | 119 |
| abstract_inverted_index.banks. | 59 |
| abstract_inverted_index.cortex | 97 |
| abstract_inverted_index.delays | 103 |
| abstract_inverted_index.effect | 86 |
| abstract_inverted_index.impact | 43, 193 |
| abstract_inverted_index.levels | 14, 71, 111 |
| abstract_inverted_index.should | 170, 182 |
| abstract_inverted_index.tissue | 5 |
| abstract_inverted_index.(GC-MS) | 63 |
| abstract_inverted_index.Tissues | 169 |
| abstract_inverted_index.between | 25, 112 |
| abstract_inverted_index.cohorts | 120 |
| abstract_inverted_index.compare | 69 |
| abstract_inverted_index.control | 128 |
| abstract_inverted_index.disease | 21 |
| abstract_inverted_index.effects | 30, 81, 137 |
| abstract_inverted_index.further | 90 |
| abstract_inverted_index.measure | 67 |
| abstract_inverted_index.minimum | 187 |
| abstract_inverted_index.periods | 147 |
| abstract_inverted_index.samples | 26 |
| abstract_inverted_index.studies | 9 |
| abstract_inverted_index.tissues | 78, 134, 164 |
| abstract_inverted_index.unknown | 29 |
| abstract_inverted_index.Analysis | 131 |
| abstract_inverted_index.However, | 23 |
| abstract_inverted_index.analyses | 161 |
| abstract_inverted_index.analysis | 93 |
| abstract_inverted_index.controls | 115, 181 |
| abstract_inverted_index.minimize | 191 |
| abstract_inverted_index.obtained | 50 |
| abstract_inverted_index.results. | 168 |
| abstract_inverted_index.staging. | 130 |
| abstract_inverted_index.variable | 122 |
| abstract_inverted_index.Cingulate | 47 |
| abstract_inverted_index.collected | 100 |
| abstract_inverted_index.controls, | 55 |
| abstract_inverted_index.determine | 80 |
| abstract_inverted_index.following | 101 |
| abstract_inverted_index.variables | 196 |
| abstract_inverted_index.Metabolite | 110 |
| abstract_inverted_index.cerebellum | 99 |
| abstract_inverted_index.conditions | 17 |
| abstract_inverted_index.identified | 144 |
| abstract_inverted_index.metabolite | 13, 32, 199 |
| abstract_inverted_index.replicable | 118, 167 |
| abstract_inverted_index.variables. | 46, 84 |
| abstract_inverted_index.alterations | 11 |
| abstract_inverted_index.influencing | 198 |
| abstract_inverted_index.metabolites | 75, 145 |
| abstract_inverted_index.post-mortem | 3, 102 |
| abstract_inverted_index.significant | 136 |
| abstract_inverted_index.variability | 24 |
| abstract_inverted_index.characterize | 41 |
| abstract_inverted_index.identifiable | 74 |
| abstract_inverted_index.investigated | 91 |
| abstract_inverted_index.metabolomics | 160 |
| abstract_inverted_index.spectrometry | 62 |
| abstract_inverted_index.variability. | 200 |
| abstract_inverted_index.Alzheimer’s | 20 |
| abstract_inverted_index.indispensable | 7 |
| abstract_inverted_index.investigating | 10 |
| abstract_inverted_index.concentrations. | 33 |
| abstract_inverted_index.gender-matched, | 176 |
| abstract_inverted_index.gender-matching, | 125 |
| abstract_inverted_index.neurodegenerative | 16 |
| abstract_inverted_index.tissue-collection | 83 |
| abstract_inverted_index.chromatography-mass | 61 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 95 |
| corresponding_author_ids | https://openalex.org/A5029480517 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 9 |
| corresponding_institution_ids | https://openalex.org/I2799725268, https://openalex.org/I28407311 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.4000000059604645 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.78255507 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |