Effects of perioperative clinical hypnosis on heart rate variability in patients undergoing oncologic surgery: secondary outcomes of a randomized controlled trial Article Swipe
Muhammad Abid Azam
,
Aliza Weinrib
,
P. Maxwell Slepian
,
Brittany N. Rosenbloom
,
Anna Waisman
,
Hance Clarke
,
Joel Katz
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3389/fpain.2024.1354015
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3389/fpain.2024.1354015
Introduction Clinical hypnosis has been proposed for post-surgical pain management for its potential vagal-mediated anti-inflammatory properties. Evidence is needed to understand its effectiveness for post-surgical recovery. Iin this secondary outcome study, it was hypothesized that surgical oncology patients randomized to receive perioperative clinical hypnosis (CH) would demonstrate greater heart-rate variability (HRV) during rest and relaxation at a 1-month post-surgery assessment compared to a treatment-as-usual group (TAU). Methods After REB approval, trial registration and informed consent, 92 participants were randomized to receive CH ( n = 45) or TAU ( n = 47). CH participants received a CH session before surgery and during post-surgical in-hospital stay HRV was assessed during rest (5 min) and relaxation (10 min) before and 1-month after surgery. Pain intensity was obtained using a 0–10 numeric rating scale pre and post 1-week and 1-month post surgery. Results One month after surgery, HRV was significantly higher in CH group ( n = 29) during rest and relaxation (both p < 0.05, d = 0.73) than TAU group ( n = 28). By contrast, rest and relaxation HRV decreased from pre- to 1-month post-surgery for the TAU (both p < 0.001, d > 0.48) but not the CH group. Pain intensity increased from pre-surgery to 1-week post-surgery ( p < 0.001, d = 0.50), and decreased from 1-week to 1-month post-surgery ( p = 0.005, d = 0.21) for all participants. Discussion The results suggest that hypnosis prevents the deleterious effects of surgery on HRV by preserving pre-operative vagal activity. These findings underscore the potential of clinical hypnosis in mitigating the adverse effects of surgery on autonomic function and may have significant implications for enhancing post-surgical recovery and pain management strategies. Clinical Trial Registration ClinicalTrials.gov , identifier (NCT03730350).
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3389/fpain.2024.1354015
- https://www.frontiersin.org/articles/10.3389/fpain.2024.1354015/pdf?isPublishedV2=False
- OA Status
- gold
- Cited By
- 7
- References
- 40
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4392593200
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4392593200Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3389/fpain.2024.1354015Digital Object Identifier
- Title
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Effects of perioperative clinical hypnosis on heart rate variability in patients undergoing oncologic surgery: secondary outcomes of a randomized controlled trialWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-03-08Full publication date if available
- Authors
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Muhammad Abid Azam, Aliza Weinrib, P. Maxwell Slepian, Brittany N. Rosenbloom, Anna Waisman, Hance Clarke, Joel KatzList of authors in order
- Landing page
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https://doi.org/10.3389/fpain.2024.1354015Publisher landing page
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https://www.frontiersin.org/articles/10.3389/fpain.2024.1354015/pdf?isPublishedV2=FalseDirect link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.frontiersin.org/articles/10.3389/fpain.2024.1354015/pdf?isPublishedV2=FalseDirect OA link when available
- Concepts
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Medicine, Perioperative, Randomized controlled trial, Heart rate variability, Hypnosis, Anesthesia, Heart rate, Relaxation (psychology), Clinical trial, Surgery, Physical therapy, Internal medicine, Blood pressure, Alternative medicine, PathologyTop concepts (fields/topics) attached by OpenAlex
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7Total citation count in OpenAlex
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2025: 7Per-year citation counts (last 5 years)
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40Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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